CAS 154229-21-7

17-(3-Pyridinyl)androsta-4,16-dien-3-one

Description:

17-(3-Pyridinyl)androsta-4,16-dien-3-one, with the CAS number 154229-21-7, is a synthetic steroid compound that belongs to the class of androgens. This compound features a steroid backbone with a pyridine ring substituted at the 17-position, which contributes to its unique biological activity. It is characterized by its specific structural modifications, including a conjugated diene system between the 4 and 16 positions, and a ketone functional group at the 3-position. These structural features are significant for its interaction with androgen receptors, potentially influencing its efficacy and potency as an androgenic agent. The compound is of interest in medicinal chemistry and pharmacology, particularly for its potential applications in hormone-related therapies and research. Its solubility, stability, and reactivity can vary based on the solvent and conditions, making it essential to consider these factors in experimental settings. As with many steroid derivatives, safety and regulatory considerations are paramount when handling or utilizing this compound in research or therapeutic contexts.

Formula: C₂₄H₂₉NO

InChI: InChI=1S/C24H29NO/c1-23-11-9-18(26)14-17(23)5-6-19-21-8-7-20(16-4-3-13-25-15-16)24(21,2)12-10-22(19)23/h3-4,7,13-15,19,21-22H,5-6,8-12H2,1-2H3/t19-,21-,22-,23-,24+/m0/s1

InChI key: InChIKey=GYJZZAJJENTSTP-NHFPKVKZSA-N

SMILES: C[C@@]12[C@]([C@]3([C@@]([C@]4(C)C(CC3)=CC(=O)CC4)(CC1)[H])[H])(CC=C2C=5C=CC=NC5)[H]

Synonyms:

• 17-(3-Pyridinyl)androsta-4,16-dien-3-one
• 17-(Pyridin-3-Yl)Androsta-4,16-Dien-3-One
• Androsta-4,16-dien-3-one, 17-(3-pyridinyl)-
• Cb 7627
• Δ4-Abiraterone
• 17-(3-Pyridyl)androsta-5,16-dien-3-one

17-(3-pyridinyl)-androsta-4,16-diene-3-one

CAS: 154229-21-7

Formula: C₂₄H₂₉NO

Purity: 98%

Color and Shape: Solid

Molecular weight: 347.4932

Ref: IN-DA0032O3

D4-abiraterone

CAS: 154229-21-7

D4-abiraterone

Purity: ≥95%

Molecular weight: 347.5g/mol

Ref: 54-OR1031604

D4-abiraterone

CAS: 154229-21-7

D4-abiraterone is the active metabolite of abiraterone.Δ4-Abiraterone is a inhibitor of CYP17A1, 3β-HSD and SRD5A, and an antagonist of the androgen receptor.

Formula: C₂₄H₂₉NO

Purity: 99.75% - 99.8%

Color and Shape: Solid

Molecular weight: 347.49

Ref: TM-T10946

Abiraterone Impurity 17

CAS: 154229-21-7

Formula: C₂₄H₂₉NO

Molecular weight: 347.50

Ref: 4Z-A-8255

17-(3-Pyridinyl)-androsta-4,16-dien-3-one

Controlled Product

CAS: 154229-21-7

Formula: C₂₄H₂₉NO

Color and Shape: Neat

Molecular weight: 347.49

Ref: TR-P991885

17-(3-PYRIDINYL)-ANDROSTA-4,16-DIENE-3-ONE

CAS: 154229-21-7

Purity: 98%

Molecular weight: 347.5020142

Ref: 10-F795058

17-(3-Pyridyl)androsta-5,16-dien-3-one

Controlled Product

CAS: 154229-21-7

17-(3-Pyridyl)androsta-5,16-dien-3-one is a synthetic steroid that has been shown to inhibit the synthesis of androgens in prostate cancer cells. It acts by competitive inhibition of 3β-hydroxysteroid dehydrogenase, which is an enzyme that converts progesterone into 17α, 20α-dihydroprogesterone. This drug also inhibits the production of testosterone by binding to cytochromes P450 and prevents its conversion into dihydrotestosterone. The drug has been shown to be effective against resistant prostate cancer cells in vitro as well as in vivo models with ventral prostates. It also has anti-inflammatory properties due to its ability to inhibit prostaglandin synthesis and decrease the expression of inflammatory cytokines such as IL1β.

Purity: Min. 95%

Ref: 3D-FP158433

3-Keto Abiraterone

CAS: 154229-21-7

Formula: C₂₄H₂₉NO

Molecular weight: 347.5

Ref: ST-EA-CP-A67047