CAS 15446-43-2

NEAMINE HYDROCHLORIDE

Description:

Neamine hydrochloride is a chemical compound that belongs to the class of aminoglycoside antibiotics. It is derived from neomycin and is characterized by its basic structure, which includes multiple amino groups that contribute to its biological activity. As a hydrochloride salt, it is typically presented as a white to off-white crystalline powder that is soluble in water, making it suitable for various pharmaceutical formulations. Neamine hydrochloride exhibits antibacterial properties, primarily effective against a range of Gram-negative and some Gram-positive bacteria, and is often used in research and clinical settings. Its mechanism of action involves inhibiting bacterial protein synthesis by binding to the 30S ribosomal subunit. Safety and handling precautions are essential due to its potential toxicity, particularly in high doses or prolonged exposure. As with many aminoglycosides, it may have side effects, including nephrotoxicity and ototoxicity, necessitating careful monitoring during therapeutic use. Overall, neamine hydrochloride is a significant compound in the field of microbiology and pharmacology.

Formula: C₁₂H₃₀Cl₄N₄O₆

(2R,3S,4R,5R,6R)-5-Amino-2-(aminomethyl)-6-{[(1R,2R,3S,4R,6S)-4,6-diamino-2,3-dihydroxycyclohexyl]oxy}oxane-3,4-diol tetrahydrochloride

CAS: 15446-43-2

Formula: C₁₂H₃₀Cl₄N₄O₆

Purity: 97%

Color and Shape: Solid

Molecular weight: 468.2018

Ref: IN-DA00ADHY

Neamine hydrochloride

CAS: 15446-43-2

Formula: C₁₂H₂₆N₄O₆

Purity: ≥ 98.0%

Color and Shape: Off-white to dark yellow powder

Molecular weight: 322.36

Ref: 7W-GC2347

Neamine tetrahydrochloride

CAS: 15446-43-2

Neamine tetrahydrochloride

Purity: ≥98%

Molecular weight: 468.2g/mol

Ref: 54-BUP13880

Neamine tetrahydrochloride

CAS: 15446-43-2

Neamine tetrahydrochloride has antimicrobial and neuroprotective activities and inhibits the growth of pancreatic cancer cells.

Formula: C₁₂H₃₀Cl₄N₄O₆

Purity: 98.98% - 99.09%

Color and Shape: Solid

Molecular weight: 468.2

Ref: TM-T36182

Neamine Hydrochloride

CAS: 15446-43-2

Formula: C₁₂H₂₆N₄O₆·XHCL

Purity: 95%~99%

Molecular weight: 322.4(base)

Ref: BP-BPI009

Neamine hydrochloride

CAS: 15446-43-2

Neamine hydrochloride is a semisynthetic aminoglycoside antibiotic, which is derived from neomycin. It exerts its antibacterial effects by interacting with bacterial ribosomal RNA, leading to the inhibition of protein synthesis. This interference results in the disruption of vital cellular processes within susceptible bacteria, ultimately causing cell death.

Formula: C₁₂H₂₆N₄O₆•(HCl)₄

Purity: Min. 80%

Color and Shape: Powder

Molecular weight: 468.2 g/mol

Ref: 3D-ON16477

Neamine Hydrochloride

CAS: 15446-43-2

Formula: C₁₂H₂₆N₄O₆(HCl)

Molecular weight: 322.36 : 4(36.5)

Ref: ST-EA-CP-N75001