CAS 154563-54-9

N-[3,5-Bis(trifluoromethyl)phenyl]-2-chloro-4-(trifluoromethyl)-5-pyrimidinecarboxamide

Description:

N-[3,5-Bis(trifluoromethyl)phenyl]-2-chloro-4-(trifluoromethyl)-5-pyrimidinecarboxamide, with CAS number 154563-54-9, is a synthetic organic compound characterized by its complex structure featuring both pyrimidine and aromatic components. This compound contains multiple trifluoromethyl groups, which significantly enhance its lipophilicity and may influence its biological activity. The presence of a chloro substituent adds to its reactivity and potential applications in medicinal chemistry. Typically, compounds with such structural features are investigated for their pharmacological properties, particularly in the development of agrochemicals or pharmaceuticals. The trifluoromethyl groups are known to impart unique electronic properties, making the compound of interest in various chemical reactions and applications. Additionally, the compound's stability and solubility characteristics can be influenced by its functional groups, which are crucial for determining its behavior in biological systems or industrial applications. Overall, this compound exemplifies the intricate design often employed in the synthesis of molecules aimed at specific chemical and biological functions.

Formula: C₁₄H₅ClF₉N₃O

InChI: InChI=1S/C14H5ClF9N3O/c15-11-25-4-8(9(27-11)14(22,23)24)10(28)26-7-2-5(12(16,17)18)1-6(3-7)13(19,20)21/h1-4H,(H,26,28)

InChI key: GHMKQBWHPQMXSH-UHFFFAOYSA-N

SMILES: C1=C(C=C(C=C1C(F)(F)F)NC(=O)C2=CN=C(N=C2C(F)(F)F)Cl)C(F)(F)F

Synonyms:

• N-[3,5-Bis(trifluoromethyl)phenyl]-2-chloro-4-(trifluoromethyl)-5-pyrimidinecarboxamide
• SP 100030
• 5-Pyrimidinecarboxamide, N-[3,5-bis(trifluoromethyl)phenyl]-2-chloro-4-(trifluoromethyl)-

SP-100030

CAS: 154563-54-9

SP-100030

Formula: C₁₄H₅ClF₉N₃O

Purity: 99.5%

Molecular weight: 437.65

Ref: 54-BUP03415

SP-100030

CAS: 154563-54-9

Formula: C₁₄H₅ClF₉N₃O

Purity: 99%

Color and Shape: Solid

Molecular weight: 437.6476

Ref: IN-DA01ENM9

SP-100030

CAS: 154563-54-9

N-(3,5-Bis(trifluoromethyl)phenyl)-2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxamide

Formula: C₁₄H₅ClF₉N₃O

Purity: 99%

Molecular weight: 437.65

Ref: IN-DG01136993

SP 100030

Controlled Product

CAS: 154563-54-9

Formula: C₁₄H₅ClF₉N₃O

Color and Shape: Neat

Molecular weight: 437.648

Ref: TR-S681738

SP-100030

CAS: 154563-54-9

SP-100030: Strong NF-κB/AP-1 inhibitor, IC50=50 nM. Reduces IL-2, IL-8, TNF-alpha, and murine CIA.

Formula: C₁₄H₅ClF₉N₃O

Purity: 99.79%

Color and Shape: Solid

Molecular weight: 437.65

Ref: TM-T24816

SP 100030

CAS: 154563-54-9

SP 100030 is a reactive, nonsteroidal anti-inflammatory drug that is used for the treatment of inflammatory bowel disease. SP 100030 binds to receptors on immune cells and inhibits their activation. The drug also blocks the production of pro-inflammatory cytokines, such as TNF-α and IL-1β, by inhibiting protein synthesis. SP 100030 has been shown to inhibit the growth of cancer cells in animal models, but it does not have any effect on the growth of normal cells. The mechanism of action is not yet known.

Formula: C₁₄H₅ClF₉N₃O

Purity: Min. 95%

Molecular weight: 437.65 g/mol

Ref: 3D-EGA56354