CAS 15532-75-9

1-[3-(Trifluoromethyl)phenyl]piperazine

Description:

1-[3-(Trifluoromethyl)phenyl]piperazine, with the CAS number 15532-75-9, is a chemical compound characterized by its piperazine core, which is a six-membered ring containing two nitrogen atoms. The presence of a trifluoromethyl group (-CF3) attached to a phenyl ring significantly influences its chemical properties, enhancing lipophilicity and potentially affecting its biological activity. This compound is often studied in medicinal chemistry due to its structural similarity to various pharmacologically active substances. It may exhibit properties such as acting as a ligand for certain receptors or influencing neurotransmitter systems. The trifluoromethyl group can also impart unique reactivity and stability, making it a valuable moiety in drug design. Additionally, the compound's solubility, melting point, and boiling point can vary based on its interactions with solvents and other chemical entities. Overall, 1-[3-(Trifluoromethyl)phenyl]piperazine serves as an important building block in the synthesis of more complex molecules in pharmaceutical research.

Formula: C₁₁H₁₃F₃N₂

InChI: InChI=1S/C11H13F3N2/c12-11(13,14)9-2-1-3-10(8-9)16-6-4-15-5-7-16/h1-3,8,15H,4-7H2

InChI key: InChIKey=KKIMDKMETPPURN-UHFFFAOYSA-N

SMILES: C(F)(F)(F)C=1C=C(C=CC1)N2CCNCC2

Synonyms:

• 1-(3-(Trifluromethyl)phenyl)piperazine
• 1-(3-Trifluoromethyl)phenylpiperazine
• 1-(3-Trifluoromethylphenyl)piperazine
• 1-(α,α,α-Trifluoro-m-tolyl)piperazine
• 1-[3-(Trifluoromethyl)phenyl]piperazine
• 1-[m-(Trifluoromethyl)phenyl]piperazine
• 3-(1-Piperazino)benzotrifluoride
• 3-(1-Piperazino)benzotrifluoride~N-(alpha,alpha,alpha-Trifluoro-m-tolyl)piperazine
• 4-[3-(Trifluoromethyl)Phenyl]Piperazin-1-Ium
• 4-[3-(Trifluoromethyl)phenyl]piperazine
• Cd 3-3015
• N-(3-Trifluoromethylphenyl)piperazine
• N-(m-Trifluoromethylphenyl)piperazine
• N-(α,α,α-Trifluoro-m-tolyl)piperazine
• NSC 128882
• Piperazine, 1-(α,α,α-trifluoro-m-tolyl)-
• Piperazine, 1-[3-(trifluoromethyl)phenyl]-
• Tfmpp
• Trifluoromethyl phenyl piperazine
• Trifluoromethylphenylpiperazine
• m-Trifluoromethylphenylpiperazine
• n-3-Triflouromethylphenyl piperazine

N-(α,α,α-Trifluoro-m-tolyl)piperazine

CAS: 15532-75-9

Formula: C₁₁H₁₃F₃N₂

Purity: ≥ 98.0%

Color and Shape: Colourless to yellow liquid

Molecular weight: 230.23

Ref: 7W-GK7766

1-(3-Trifluoromethylphenyl)piperazine free base

Controlled Product

CAS: 15532-75-9

1-(3-Trifluoromethylphenyl)piperazine free base is a potent 5-HT2 receptor agonist. It has been shown to be a potent activator of the 5-HT2A receptor in primary cells and may exhibit physiological effects. This compound is used as an analytical reference standard for the measurement of serotonin levels in biological samples, such as human serum or platelets. 1-(3-Trifluoromethylphenyl)piperazine free base has been studied as a drug in humans for the treatment of autoimmune diseases and depression, but is not yet marketed. The drug has also been shown to have locomotor activity, which may be due to its ability to stimulate the 5-HT2 receptors.

Formula: C₁₁H₁₃F₃N₂

Purity: Min. 95%

Color and Shape: Clear Liquid

Molecular weight: 230.23 g/mol

Ref: 3D-FT05850

Piperazine, 1-[3-(trifluoromethyl)phenyl]-

CAS: 15532-75-9

Formula: C₁₁H₁₃F₃N₂

Molecular weight: 230.2295

Ref: IN-DA001NU4