CAS 15574-96-6

Pizotifen

Description:

Pizotifen is a chemical compound primarily used as an antihistamine and a preventive treatment for migraines. It belongs to the class of drugs known as serotonin receptor antagonists and is particularly effective in blocking the action of serotonin, which is implicated in migraine pathophysiology. The substance is typically administered in oral form and is known for its sedative properties, which can lead to drowsiness as a common side effect. Pizotifen is characterized by its ability to inhibit the release of certain neurotransmitters, thereby reducing the frequency and severity of migraine attacks. Its chemical structure includes a piperidine ring, contributing to its pharmacological activity. Additionally, it has been noted for its potential to stimulate appetite, which can be a consideration in its therapeutic use. As with any medication, it is important to consider contraindications and potential interactions with other drugs when prescribing or using pizotifen.

Formula: C₁₉H₂₁NS

InChI: InChI=1S/C19H21NS/c1-20-11-8-15(9-12-20)19-16-5-3-2-4-14(16)6-7-18-17(19)10-13-21-18/h2-5,10,13H,6-9,11-12H2,1H3

InChI key: InChIKey=FIADGNVRKBPQEU-UHFFFAOYSA-N

SMILES: CN1CCC(=C2C3=C(CCC=4C2=CC=CC4)SC=C3)CC1

Synonyms:

• 4-(1-Methyl-4-piperidylidene)-9,10-dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thiophene
• 4-(9,10-Dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thien-4-ylidene)-1-methylpiperidine
• 4-(9,10-dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thiophen-4-ylidene)-1-methylpiperidine
• 4H-Benzo[4,5]cyclohepta[1,2-b]thiophene, piperidine deriv.
• Bc 105
• Litec
• Piperidine, 4-(9,10-dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thien-4-ylidene)-1-methyl-
• Pizotyline
• Polomigran
• Sandomigran
• Sanomigran

Pizotifen

CAS: 15574-96-6

Formula: C₁₉H₂₁NS

Purity: >98.0%(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 295.44

Ref: 3B-P2344

1-methyl-4-{6-thiatricyclo[8.4.0.0^{3,7}]tetradeca-1(10),3(7),4,11,13-pentaen-2-ylidene}piperidine

CAS: 15574-96-6

Formula: C₁₉H₂₁NS

Purity: 98%

Color and Shape: Solid

Molecular weight: 295.4417

Ref: IN-DA001O5K

Pizotifen

CAS: 15574-96-6

Pizotifen is a serotonin antagonist with mild anticholinergic effects, used in migraine prevention. Not available in the USA.

Formula: C₁₉H₂₁NS

Purity: 99.93%

Color and Shape: Solid

Molecular weight: 295.44

Ref: TM-T1442

4-(9,10-Dihydro-4H-Benzo[4,5]Cyclohepta[1,2-B]Thiophen-4-Ylidene)-1-Methylpiperidine

CAS: 15574-96-6

4-(9,10-Dihydro-4H-Benzo[4,5]Cyclohepta[1,2-B]Thiophen-4-Ylidene)-1-Methylpiperidine

Purity: 99%

Molecular weight: 295.44g/mol

Ref: 54-OR1025544

Pizotifen

CAS: 15574-96-6

Formula: C₁₉H₂₁NS

Molecular weight: 295.44

Ref: 7W-GP7109

Pizotifen

CAS: 15574-96-6

Pizotifen

Purity: ≥98%

Molecular weight: 295.44g/mol

Ref: 54-BUP15900

Pizotyline

Controlled Product

CAS: 15574-96-6

Applications Serotonin antagonist structurally related to Cyproheptadine. Antimigraine; appetite stimulant.
References Geraud, G., et al.: Clin. Ther., 26, 1305 (2004), Bolay, H., et al.: Nat. Med., 8, 136 (2002), Scher, A., et al.: Pain, 106, 81 (2003), Richter, F., et al.: J. Cereb. Blood Flow Metab., 25, 1225 (2005),

Formula: C₁₉H₂₁NS

Color and Shape: Neat

Molecular weight: 295.44

Ref: TR-P552800

Pizotifen - Bio-X ™

CAS: 15574-96-6

Pizotifen is an anti-migraine agent. This drug is a serotonin and tryptamine antagonist drug that is used for the treatment of migraines. Pizotifen also exhibits anticholinergic and antihistamine properties. This drug blocks 5-HT receptors allowing for cranial vasoconstriction.

Formula: C₁₉H₂₁NS

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 295.44 g/mol

Ref: 3D-BP164276

Pizotifen

CAS: 15574-96-6

5-HT2A/C serotonin receptor antagonist; anti-migraine agent; anti-histaminic

Formula: C₁₉H₂₁NS

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 295.44 g/mol

Ref: 3D-FP27096