CAS 15574-96-6
:Pizotifen
Description:
Pizotifen is a chemical compound primarily used as an antihistamine and a preventive treatment for migraines. It belongs to the class of drugs known as serotonin receptor antagonists and is particularly effective in blocking the action of serotonin, which is implicated in migraine pathophysiology. The substance is typically administered in oral form and is known for its sedative properties, which can lead to drowsiness as a common side effect. Pizotifen is characterized by its ability to inhibit the release of certain neurotransmitters, thereby reducing the frequency and severity of migraine attacks. Its chemical structure includes a piperidine ring, contributing to its pharmacological activity. Additionally, it has been noted for its potential to stimulate appetite, which can be a consideration in its therapeutic use. As with any medication, it is important to consider contraindications and potential interactions with other drugs when prescribing or using pizotifen.
Formula:C19H21NS
InChI:InChI=1S/C19H21NS/c1-20-11-8-15(9-12-20)19-16-5-3-2-4-14(16)6-7-18-17(19)10-13-21-18/h2-5,10,13H,6-9,11-12H2,1H3
InChI key:InChIKey=FIADGNVRKBPQEU-UHFFFAOYSA-N
SMILES:CN1CCC(=C2C3=C(CCC=4C2=CC=CC4)SC=C3)CC1
Synonyms:- 4-(1-Methyl-4-piperidylidene)-9,10-dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thiophene
- 4-(9,10-Dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thien-4-ylidene)-1-methylpiperidine
- 4-(9,10-dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thiophen-4-ylidene)-1-methylpiperidine
- 4H-Benzo[4,5]cyclohepta[1,2-b]thiophene, piperidine deriv.
- Bc 105
- Litec
- Piperidine, 4-(9,10-dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thien-4-ylidene)-1-methyl-
- Pizotyline
- Polomigran
- Sandomigran
- Sanomigran
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Found 11 products.
Pizotifen
CAS:Formula:C19H21NSPurity:>98.0%(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:295.441-methyl-4-{6-thiatricyclo[8.4.0.0^{3,7}]tetradeca-1(10),3(7),4,11,13-pentaen-2-ylidene}piperidine
CAS:Formula:C19H21NSPurity:98%Color and Shape:SolidMolecular weight:295.4417Pizotifen
CAS:Pizotifen is a serotonin antagonist with mild anticholinergic effects, used in migraine prevention. Not available in the USA.Formula:C19H21NSPurity:99.93%Color and Shape:SolidMolecular weight:295.444-(9,10-Dihydro-4H-Benzo[4,5]Cyclohepta[1,2-B]Thiophen-4-Ylidene)-1-Methylpiperidine
CAS:4-(9,10-Dihydro-4H-Benzo[4,5]Cyclohepta[1,2-B]Thiophen-4-Ylidene)-1-MethylpiperidineFormula:C19H21NSPurity:99%Molecular weight:295.44Pizotyline
CAS:Controlled ProductApplications Serotonin antagonist structurally related to Cyproheptadine. Antimigraine; appetite stimulant.
References Geraud, G., et al.: Clin. Ther., 26, 1305 (2004), Bolay, H., et al.: Nat. Med., 8, 136 (2002), Scher, A., et al.: Pain, 106, 81 (2003), Richter, F., et al.: J. Cereb. Blood Flow Metab., 25, 1225 (2005),Formula:C19H21NSColor and Shape:NeatMolecular weight:295.44Pizotifen
CAS:5-HT2A/C serotonin receptor antagonist; anti-migraine agent; anti-histaminic
Formula:C19H21NSPurity:Min. 95%Color and Shape:PowderMolecular weight:295.44 g/molPizotifen - Bio-X ™
CAS:Pizotifen is an anti-migraine agent. This drug is a serotonin and tryptamine antagonist drug that is used for the treatment of migraines. Pizotifen also exhibits anticholinergic and antihistamine properties. This drug blocks 5-HT receptors allowing for cranial vasoconstriction.
Formula:C19H21NSPurity:Min. 95%Color and Shape:PowderMolecular weight:295.44 g/mol
![1-methyl-4-{6-thiatricyclo[8.4.0.0^{3,7}]tetradeca-1(10),3(7),4,11,13-pentaen-2-ylidene}piperidine](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb%2FDA001O5K.jpg&w=3840&q=75)
![4-(9,10-Dihydro-4H-Benzo[4,5]Cyclohepta[1,2-B]Thiophen-4-Ylidene)-1-Methylpiperidine](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F54%2Fthumb%2FOR1025544.jpg&w=3840&q=75)
