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CAS 155976-51-5

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8-Isoprostane

Description:
8-Isoprostane, also known as 8-iso-prostaglandin F2α, is a bioactive lipid molecule that is classified as an isoprostane, a type of prostaglandin-like compound formed through the non-enzymatic oxidation of arachidonic acid. It is characterized by its role as a marker of oxidative stress and lipid peroxidation in biological systems. The presence of 8-Isoprostane in biological fluids, such as urine and plasma, is often used as an indicator of oxidative damage and has been implicated in various pathological conditions, including cardiovascular diseases and neurodegenerative disorders. This compound exhibits potent biological activities, including vasoconstriction and modulation of inflammatory responses. Its structure features a cyclopentane ring with specific functional groups that contribute to its reactivity and biological effects. Due to its significance in research and clinical settings, 8-Isoprostane is often studied for its potential as a biomarker for oxidative stress and its implications in disease progression and diagnosis.
Formula:C20H40
InChI:InChI=1S/C20H40/c1-3-5-7-9-11-13-16-20-18-14-17-19(20)15-12-10-8-6-4-2/h19-20H,3-18H2,1-2H3/t19-,20+/m1/s1
InChI key:InChIKey=UKVVPDHLUHAJNZ-UXHICEINSA-N
SMILES:C(CCCCCCC)[C@@H]1[C@H](CCCCCCC)CCC1
Synonyms:
  • 8-Isoprostane
  • Prostane, (8β)-
  • (8β)-Prostane
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