CAS 15622-65-8

Molindone hydrochloride

Description:

Molindone hydrochloride is an antipsychotic medication primarily used in the treatment of schizophrenia. It belongs to the class of compounds known as indole derivatives and exhibits a unique mechanism of action, primarily functioning as a dopamine receptor antagonist. This compound is characterized by its ability to modulate neurotransmitter activity in the brain, which helps alleviate symptoms associated with psychotic disorders. Molindone hydrochloride is typically administered in its hydrochloride salt form, enhancing its solubility and bioavailability. The substance is known for its relatively low sedative effects compared to other antipsychotics, making it a preferred option for some patients. Additionally, it has a favorable side effect profile, although it can still cause extrapyramidal symptoms and other adverse effects. The chemical structure includes a piperidine ring, contributing to its pharmacological properties. As with any medication, it is essential for patients to be monitored for efficacy and side effects during treatment.

Formula: C₁₆H₂₅ClN₂O₂

InChI: InChI=1/C16H24N2O2.ClH/c1-3-13-11(2)17-14-5-4-12(16(19)15(13)14)10-18-6-8-20-9-7-18;/h12,17H,3-10H2,1-2H3;1H

InChI key: InChIKey=GQWNECFJGBQMBO-UHFFFAOYSA-N

SMILES: C(C)C=1C2=C(NC1C)CCC(CN3CCOCC3)C2=O.Cl

Synonyms:

• 3-Ethyl-2-methyl-5-(morpholinomethyl)-6,7-dihydro-1H-indol-4(5H)-one hydrochloride
• 3-Ethyl-2-methyl-5-[(morpholin-4-yl)methyl]-4,5,6,7-tetrahydro-1H-indol-4-one hydrochloride
• 3-Ethyl-6,7-Dihydro-2-Methyl-5-(Morpholinomethyl)-Indol-4(5H)-Onmonohydroc
• 3-Ethyl-6,7-Dihydro-2-Methyl-5-Morpholinomethylindol-4(5H)-Onehydrochloride
• 3-Ethyl-6,7-Dihydro-2-Methyl-5-Morpholinomethylindole-4(5H)-Onehydrochloride
• 4-[(3-ethyl-2-methyl-4-oxo-4,5,6,7-tetrahydro-1H-indol-5-yl)methyl]morpholin-4-ium chloride
• 4H-Indol-4-one, 3-ethyl-1,5,6,7-tetrahydro-2-methyl-5-(4-morpholinylmethyl)-, hydrochloride (1:1)
• 4H-Indol-4-one, 3-ethyl-1,5,6,7-tetrahydro-2-methyl-5-(4-morpholinylmethyl)-, monohydrochloride
• En 1733A
• Indol-4(5H)-one, 3-ethyl-6,7-dihydro-2-methyl-5-(morpholinomethyl)-, monohydrochloride
• Lidone
• Lindone
• Moban
• Molindone hydrochloride
• MOLINDONE HCL USP/EP/BP
• MolindoneHydrochloride&gt
• MOBAN;EN-1733A
• MOLINDONE HYDROCHLORIDE (500 MG)
• 3-Ethyl-1,5,6,7-tetrahydro-2-methyl-5-(4-morpholinylmethyl)-4H-indol-4-one, hydrochloride (1:1)(For export only)
• Molindone Hydrochloride (1445459)
• 3-Ethyl-1,5,6,7-tetrahydro-2-methyl-5-(4-morpholinylmethyl)-4H-indol-4-one, hydrochloride (1:1)
• Molindone Hydrochlorid
• 3-Ethyl-6,7-dihydro-2-methyl-5-(morpholinomethyl)-1H-indol-4(5H)-one Hydrochloride

Molindone Hydrochloride

CAS: 15622-65-8

Formula: C₁₆H₂₄N₂O₂·HCl

Purity: >98.0%(HPLC)(T)

Color and Shape: White to Yellow to Orange powder to crystal

Molecular weight: 312.84

Ref: 3B-M2252

Molindone Hydrochloride

CAS: 15622-65-8

Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoi

Formula: C₁₆H₂₄N₂O₂·HCl

Color and Shape: White Off-White Powder

Molecular weight: 276.18378

Ref: 45-1445459

Molindone hydrochloride

CAS: 15622-65-8

Molindone hydrochloride (EN-1733A) is an indole derivative effective in schizophrenia and other psychoses by blocking the effects of dopamine in the brain.

Formula: C₁₆H₂₅ClN₂O₂

Purity: 99% - 99.99%

Color and Shape: Solid

Molecular weight: 312.835

Ref: TM-T0716

Molindone hydrochloride

CAS: 15622-65-8

Molindone hydrochloride

Formula: C₁₆H₂₄N₂O₂·HCl

Purity: 99.5%

Molecular weight: 312.84

Ref: 54-BUP13668

Molindone hydrochloride

CAS: 15622-65-8

Molindone hydrochloride

Formula: C₁₆H₂₅ClN₂O₂

Purity: 0.98

Molecular weight: 312.83

Ref: 54-OR1026824

Molindone HCl

CAS: 15622-65-8

Formula: C₁₆H₂₄N₂O₂·HCl

Color and Shape: Off-White Solid

Molecular weight: 276.38 36.46

Ref: 4Z-M-155001

Molindone hydrochloride

CAS: 15622-65-8

Formula: C₁₆H₂₄N₂O₂·HCl

Purity: ≥ 98.0%

Color and Shape: White to off-white solid

Molecular weight: 312.83

Ref: 7W-GP8140

Molindone.HCl, 1mg/ml in Methanol (as free base)

CAS: 15622-65-8

Formula: C₁₆H₂₄N₂O₂·ClH

Color and Shape: Colourless

Molecular weight: 312.83

Ref: LP-MOL-1886-HC-1LM

Molindone.HCl

CAS: 15622-65-8

Formula: C₁₆H₂₄N₂O₂·ClH

Color and Shape: Neat

Molecular weight: 312.83

Ref: LP-MOL-1886-HC

3-Ethyl-2-methyl-5-(morpholinomethyl)-6,7-dihydro-1H-indol-4(5H)-one hydrochloride

CAS: 15622-65-8

3-Ethyl-2-methyl-5-(morpholinomethyl)-6,7-dihydro-1H-indol-4(5H)-one hydrochloride

Formula: C₁₆H₂₅ClN₂O₂

Purity: 99%

Molecular weight: 312.83

Ref: IN-DG140247

Molindone hydrochloride

CAS: 15622-65-8

Formula: C₁₆H₂₅ClN₂O₂

Purity: >98.0%(HPLC)(T)

Molecular weight: 312.84

Ref: 10-F494213

Molindone hydrochloride

CAS: 15622-65-8

Molindone is a neuroleptic agent that has been shown to be effective in the treatment of schizophrenia. It also has antipsychotic properties and may treat other mental disorders. Molindone is a potent dopamine antagonist, which is thought to explain its therapeutic effects in these conditions. The drug is well absorbed orally and crosses the blood-brain barrier easily, making it suitable for oral administration. Molindone has been shown to have toxic effects in animal studies, including a decrease in serum prolactin levels, an increase in liver weights, and an increase in the number of animals that died during toxicity studies. These side-effect profiles are similar to those seen with haloperidol (a phenothiazine antipsychotic), which suggests that molindone may be used as an alternative to haloperidol when treating psychosis or other mental disorders.

Formula: C₁₆H₂₄N₂O₂•HCl

Purity: Min. 95%

Color and Shape: White To Light (Or Pale) Yellow To Light (Or Pale) Red Solid

Molecular weight: 312.83 g/mol

Ref: 3D-FM55422

Molindone hydrochloride

CAS: 15622-65-8

Formula: C₁₆H₂₅ClN₂O₂

Molecular weight: 312.83

Ref: BE-RMCM232001

Molindone Hydrochloride

Controlled Product

CAS: 15622-65-8

Applications D2 Dopamine receptor antagonist. MAO inhibitor. Antipsychotic.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Sugerman, H., et al.: Clin. Pharmacol. Ther., 8, 261 (1967), Claghorn, et al.: Curr. Ther. Res., 11, 524 (1969), Goldenthal, E.I., et al.: Toxicol. Appl. Pharmacol., 18, 185 (1971),

Formula: C₁₆H₂₄N₂O₂·ClH

Color and Shape: Neat

Molecular weight: 312.83

Ref: TR-M487500

Molindone Hydrochloride

CAS: 15622-65-8

Formula: C₁₆H₂₄N₂O₂HCl

Molecular weight: 276.4 : 36.46

Ref: ST-EA-CP-M43006

4H-Indol-4-one, 3-ethyl-1,5,6,7-tetrahydro-2-methyl-5-(4-morpholinylmethyl)-, hydrochloride (1:1)

CAS: 15622-65-8

Formula: C₁₆H₂₅ClN₂O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 312.8349

Ref: IN-DA001OM4