CAS 15663-27-1: Cisplatin

Description: Cisplatin, with the CAS number 15663-27-1, is a platinum-based chemotherapy drug widely used in the treatment of various cancers, including testicular, ovarian, bladder, and lung cancers. Its chemical formula is cis-[Pt(NH3)2Cl2], indicating that it consists of a platinum atom coordinated to two ammonia molecules and two chloride ions. The compound is characterized by its square planar geometry, which is crucial for its biological activity. Cisplatin functions primarily by forming DNA cross-links, thereby inhibiting DNA replication and transcription, leading to apoptosis in rapidly dividing cancer cells. It is typically administered intravenously and can have side effects such as nephrotoxicity, nausea, and myelosuppression. The drug's effectiveness can be influenced by factors such as the presence of specific cellular proteins and the tumor microenvironment. Due to its mechanism of action, cisplatin is often used in combination with other chemotherapeutic agents to enhance therapeutic efficacy and overcome resistance.

Formula: Cl₂H₆N₂Pt

InChI: InChI=1S/2ClH.2H3N.Pt/h2*1H;2*1H3;/q;;;;+2/p-2

InChI key: InChIKey=LXZZYRPGZAFOLE-UHFFFAOYSA-L

SMILES: [Cl-][Pt+2]([Cl-])([NH3])[NH3]

Synonyms:

• (SP-4-2)-Diamminedichloroplatinum
• Abiplatin
• Biocisplatinum
• Briplatin
• CP Ethypharm
• Cacp
• Cddp
• Cis-Platinum(Ii)Diammine Dichloride
• Cismaplat
• Cisplatin
• Cisplatine
• Cisplatine Mylan
• Cisplatino
• Cisplatinum
• Cisplatyl
• Citoplatino
• Citoplax
• Cpdc
• Cpdd
• Cppd
• DDP
• DDP (antitumor agent)
• DichlorodiammineplatinumIIyelloworangextl
• Fauldiscipla
• IA-call
• Kemoplat
• Lederplatin
• LiPlaCis
• Lipoplatin
• Maruko
• Neoplatin
• Nsc 119875
• Platamine
• Platiblastin
• Platidiam
• Platinex
• Platinol
• Platinol AQ
• Platinoxan
• Platinum, diamminedichloro-, (SP-4-2)-
• Platinum, diamminedichloro-, cis-
• Platinumdiamminechloride
• Platistin
• Platosin
• Rand
• Randa
• SPI 077 (complex)
• Spi 077
• Spi 077B103
• Tr 170
• cis-DDP
• cis-Diaminedichloridoplatinum(II)
• cis-Diaminedichloroplatinum
• cis-Diaminedichloroplatinum(II)
• cis-Diaminodichloroplatinum(II)
• cis-Diamminedichloroplatinum
• cis-Diamminedichloroplatinum(II)
• cis-Diammineplatinum(II)
• cis-Diammineplatinum(II) dichloride
• cis-Dichlorodiammineplatinum
• cis-Dichlorodiammineplatinum(II)
• cis-Platin
• cis-Platine
• cis-Platinous diaminodichloride
• cis-Platinum
• cis-Platinum II
• cis-Platinum diaminodichloride
• cis-Platinum(II) diaminodichloride
• cis-Platinum(II) diammine chloride
• cis-Platinum(II) diamminedichloride
• cis-Platinumdiamine dichloride
• cis-Platinumdiammine dichloride
• cis-Dichlorodiamineplatinum(II)

cis-Diammineplatinum(II) Dichloride

CAS: 15663-27-1

• Formula: H₆Cl₂N₂Pt
• Color and Shape: Light orange to Yellow to Green powder to crystal
• Molecular weight: 300.05

cis-Diamminedichloroplatinum(II), Pt 64.5% min

CAS: 15663-27-1

Being a potent anticancer agent that blocks DNA synthesis, the pharmaceutical compositions are used in …

• Formula: Cl₂H₆N₂Pt
• Purity: 64.5%
• Molecular weight: 300.04

cis-Dichlorodiammineplatinum (II), CISPLATIN (USP)

CAS: 15663-27-1

• Formula: cisPt(NH₃)₂Cl₂
• Color and Shape: yellow to orange xtl.
• Molecular weight: 300.06

cis-Dichlorodiammine platinum(II), 99% CISPLATIN

CAS: 15663-27-1

• Formula: cisPt(NH₃)₂Cl₂
• Purity: 99%
• Color and Shape: yellow to orange xtl.
• Molecular weight: 300.06

Cisplatin RS

CAS: 15663-27-1

• Formula: H₄Cl₂N₂Pt
• Color and Shape: Powder
• Molecular weight: 298.0352

Cisplatin

CAS: 15663-27-1

• Formula: Cl₂H₆N₂Pt
• Purity: 100.0%
• Color and Shape: Yellow
• Molecular weight: 298.9556

Cisplatin CRS

CAS: 15663-27-1

• Formula: H₄Cl₂N₂Pt
• Color and Shape: Powder
• Molecular weight: 298.0352

Cisplatin

CAS: 15663-27-1

Inorganic or organic compounds of precious metals, whether or not chemically defined; amalgrams of precious …

• Formula: Cl₂H₆N₂Pt
• Color and Shape: Yellow Orange Powder
• Molecular weight: 298.9556

Cisplatin

CAS: 15663-27-1

Cisplatin (CDDP) is a DNA cross-linking agent.

• Formula: Cl₂H₆N₂Pt
• Purity: 97.75% - 99.63%
• Color and Shape: Orange-Yellow To Deep Yellow Solid Or Powder
• Molecular weight: 300.04

cis-Diammineplatinum(II) dichloride

CAS: 15663-27-1

• Formula: Cl₂H₆N₂Pt
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 300.045

Cisplatin

CAS: 15663-27-1

• Purity: ≥98%
• Molecular weight: 300.04g/mol

Cisplatin

CAS: 15663-27-1

• Formula: Cl₂H₆N₂Pt
• Purity: ≥ 98.0% (anhydrous)
• Color and Shape: Yellow to orange powder
• Molecular weight: 300.06

Cisplatin

CAS: 15663-27-1

• Formula: Cl₂H₆N₂Pt
• Color and Shape: Yellow Solid
• Molecular weight: 300.05

Cisplatin, USP grade

CAS: 15663-27-1

• Formula: Cl₂H₆N₂Pt
• Purity: ≥ 4.5
• Color and Shape: Yellow to orange powder
• Molecular weight: 300.06

cis-Dichlorodiamineplatinum(II), 99.99%, (trace metal basis)

CAS: 15663-27-1

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. …

• Formula: Cl₂H₆N₂Pt
• Purity: 99.99%
• Color and Shape: Yellow to orange, Powder or crystals
• Molecular weight: 300.04

cis-Dichlorodiamine platinum(II); 99.95% (metals basis)

CAS: 15663-27-1

• Formula: Pt(NH₃)₂Cl₂
• Purity: ≥ 99.95%
• Color and Shape: Yellow to orange powder or crystals
• Molecular weight: 300.06

Cisplatin RS

CAS: 15663-27-1

• Color and Shape: Yellow Solid Crystalline Powder

Cisplatin

CAS: 15663-27-1

• Formula: Cl₂H₆N₂Pt
• Color and Shape: Neat
• Molecular weight: 300.04

Cisplatin - Bio-X ™

CAS: 15663-27-1

Cisplatin, also known as cisplatinum, is a platinum-based anti-cancer agent that inhibits the EGFR, which …

• Formula: Cl₂H₆N₂Pt
• Purity: Min. 99%
• Color and Shape: Powder
• Molecular weight: 300.05 g/mol

Cisplatin

CAS: 15663-27-1

Cisplatin is a chemotherapeutic drug that inhibits the growth of cancer cells by binding to …

• Formula: Cl₂H₆N₂Pt
• Purity: (Hplc) 98 To 102%
• Color and Shape: Yellow Powder
• Molecular weight: 300.05 g/mol