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CAS 156661-42-6

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Ac-Lys-AMC

Description:
Ac-Lys-AMC, or Acetyl-Lysine-7-amido-4-methylcoumarin, is a synthetic peptide substrate commonly used in biochemical research, particularly in studies involving proteases and enzyme activity. This compound features an acetylated lysine residue linked to a 7-amido-4-methylcoumarin fluorophore, which allows for fluorescence-based detection upon cleavage by specific enzymes. The acetyl group enhances the solubility and stability of the peptide, while the lysine residue provides a site for enzymatic action. Ac-Lys-AMC is characterized by its ability to emit fluorescence when cleaved, making it a valuable tool for monitoring proteolytic activity in various biological assays. Its applications extend to drug discovery, cell biology, and understanding protein interactions. The compound is typically used in a laboratory setting, and its handling requires standard safety precautions due to its synthetic nature. Overall, Ac-Lys-AMC serves as an important reagent in the study of enzyme kinetics and protease function.
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