CAS 156707-43-6

cys-4-(2-aminobenzoyl)-met

Description:

Cys-4-(2-aminobenzoyl)-met, identified by its CAS number 156707-43-6, is a synthetic peptide that incorporates cysteine, methionine, and an aminobenzoyl group. This compound is characterized by its unique structure, which includes a cysteine residue that can form disulfide bonds, contributing to its stability and potential biological activity. The presence of the 2-aminobenzoyl moiety suggests that it may have applications in bioconjugation or as a fluorescent probe due to the aromatic nature of the benzoyl group. Additionally, the methionine residue may play a role in the peptide's overall stability and functionality. This compound is of interest in biochemical research, particularly in the fields of drug design and development, where peptides are often explored for their therapeutic potential. Its specific properties, such as solubility, reactivity, and biological activity, would depend on the surrounding conditions and the presence of other functional groups or solvents.

Formula: C₁₅H₂₁N₃O₄S₂

Synonyms:

• H-Cys-4-Abz-Met-OH
• FTI II
• FTASE INHIBITOR II
• L-Methionine,N-[4-[[(2R)-2-aMino-3-Mercapto-1-oxopropyl]aMino]benzoyl]-
• CYSTEINE-(4-AMINOBENOZYL)METHIONINE
• (2S)-2-[[4-[[(2R)-2-amino-3-sulfanylpropanoyl]amino]benzoyl]amino]-4-methylsulfanylbutanoic acid

H-Cys-4-Abz-Met-OH

CAS: 156707-43-6

Potent inhibitor of the Ras farnesyltransferase (Ftase) with an IC₅₀ of 50 nM. It prevented farnesylation of Ras and resulted in its inability to associate with other cell signaling components at the interior of the plasma membrane microenvironment.

Formula: C₁₅H₂₁N₃O₄S₂

Purity: 94.0%

Molecular weight: 371.48

Ref: 01-4026861

L-Methionine, N-[4-[[(2R)-2-amino-3-mercapto-1-oxopropyl]amino]benzoyl]-

CAS: 156707-43-6

Formula: C₁₅H₂₁N₃O₄S₂

Color and Shape: Solid

Molecular weight: 371.4749

Ref: IN-DA001OXA

H-Cys-4-Abz-Met-OH

CAS: 156707-43-6

H-Cys-4-Abz-Met-OH is a novel small molecule that binds to the SH2 domain of the human protein tyrosine phosphatase 1B (PTP1B). The binding of this molecule inhibits PTP1B activity and prevents it from dephosphorylating phosphotyrosine, which is an important step in the signalling pathway. This inhibition leads to the activation of downstream signaling pathways, including those involved in the regulation of cell growth and differentiation. H-Cys-4-Abz-Met-OH has been shown to be effective at inhibiting breast cancer cell growth in vitro.

Formula: C₁₅H₂₁N₃O₄S₂

Purity: Min. 95%

Molecular weight: 371.48 g/mol

Ref: 3D-FC109033