CAS 15676-16-1

(+-)-sulpiride

Description:

(±)-Sulpiride is a substituted benzamide derivative primarily used as an antipsychotic medication. It exhibits characteristics typical of a dopamine antagonist, particularly affecting the D2 dopamine receptors in the central nervous system. This compound is known for its efficacy in treating various psychiatric disorders, including schizophrenia and depression, by modulating dopaminergic activity. (±)-Sulpiride is a chiral molecule, meaning it exists in two enantiomeric forms, which can exhibit different pharmacological effects. The substance is typically administered orally and is well-absorbed in the gastrointestinal tract. Its pharmacokinetics include a relatively long half-life, allowing for once or twice daily dosing. In terms of solubility, (±)-sulpiride is generally soluble in water and organic solvents, which facilitates its formulation in various pharmaceutical preparations. Side effects may include sedation, weight gain, and extrapyramidal symptoms, although these are often less pronounced compared to other antipsychotics. Overall, (±)-sulpiride is a significant compound in psychopharmacology, with a unique profile that distinguishes it from other antipsychotic agents.

Formula: C₁₅H₂₃N₃O₄S

InChI: InChI=1/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21)/p+1/t11-/m1/s1

InChI key: InChIKey=BGRJTUBHPOOWDU-UHFFFAOYSA-N

SMILES: C(NCC1N(CC)CCC1)(=O)C2=C(OC)C=CC(S(N)(=O)=O)=C2

Synonyms:

• (+/-)-N-1-(Ethylpyrrolidin-2-Ylmethyl)-2-Methoxy-5-Sulfamoylbenzamide
• (2R)-1-ethyl-2-({[(2-methoxy-5-sulfamoylphenyl)carbonyl]amino}methyl)pyrrolidinium
• (2S)-1-ethyl-2-({[(2-methoxy-5-sulfamoylphenyl)carbonyl]amino}methyl)pyrrolidinium
• (Rs)-(+/-)-5-Aminosulfonyl-N-[(1-Ethyl-2-Pyrrolidinyl)Methyl]-2-Methoxybenzamide
• (Rs)-(+/-)-Sulpiride
• 5-(Aminosufonyl)-N-[(1-Ethyl-2-Pyrrolidinyl)Methyl]-2-Methoxybenzamide
• 5-(Aminosulfonyl)-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2-methoxybenzamide
• <span class="text-smallcaps">DL</span>-Sulpiride
• Abilit
• Aiglonyl
• Benzamide, 5-(aminosulfonyl)-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2-methoxy-
• Coolspan
• DL-Sulpiride
• Dobren
• Dogmatil
• Dogmatyl
• Dogmil
• Dolmatil
• Eglonyl
• Guastil
• Meresa
• Miradol
• Mirbanil
• Misulvan
• N-((1-ethylpyrrolidin-2-yl)methyl)-2-methoxy-5-sulfamoylbenzamide
• N-(1-Ethyl-2-pyrrolidinylmethyl)-2-methoxy-5-sulfamidobenzamide
• N-(1-Ethyl-pyrrolidin-2-ylmethyl)-2-methoxy-5-sulfamoyl-benzamide
• N-[(1-Ethyl-2-pyrrolidinyl)methyl]-5-sulfamoyl-o-anisamide
• N-[(1-ethyl-2-pyrrolidinyl)methyl]-2-methoxy-5-sulfamoylbenzamide
• N-[(1-ethylpyrrolidin-3-yl)methyl]-2-methoxy-5-sulfamoylbenzamide
• Neogama
• Omperan
• Pyrikappl
• Rd 1403
• Sernevin
• Splotin
• Sulpirid
• Sulpirida
• Sulpitil
• Sulpyrid
• Sursumid
• Synedil
• Trilan
• o-Anisamide, N-[(1-ethyl-2-pyrrolidinyl)methyl]-5-sulfamoyl-
• SULPIRIDE
• (+/-)-SULPIRIDE
• Sulpiride
• (+/-)-5-AMINOSULFONYL-N-([1-ETHYL-2-PYRROLIDINYL)METHYL]-2-METHOXY-BENZAMIDE
• Levobren

Sulpiride

CAS: 15676-16-1

Sulpiride

Formula: C₁₅H₂₃N₃O₄S

Purity: 100%

Color and Shape: Off-White

Molecular weight: 341.14093

Ref: 47-679

SULPIRIDE CRS

CAS: 15676-16-1

SULPIRIDE CRS

Formula: C₁₅H₂₃N₃O₄S

Color and Shape: Crystalline Powder. White. Powder.

Molecular weight: 341.4258

Ref: 41-S2190000

Sulpiride

CAS: 15676-16-1

Sulpiride

Formula: C₁₅H₂₃N₃O₄S

Purity: >98%

Molecular weight: 341.43

Ref: 54-OR1026960

Sulpiride

CAS: 15676-16-1

Sulpiride (Aiglonyl) is a dopamine D2-receptor antagonist, used therapeutically as an antidepressant, antipsychotic, and as a digestive aid.

Formula: C₁₅H₂₃N₃O₄S

Purity: 99.94%

Color and Shape: White Crystalline Powder

Molecular weight: 341.43

Ref: TM-T1201

Sulpiride

CAS: 15676-16-1

Sulpiride

Formula: C₁₅H₂₃N₃O₄S

Purity: ≥98%

Molecular weight: 341.43

Ref: 54-BUP14922

Sulpiride

CAS: 15676-16-1

Formula: C₁₅H₂₃N₃O₄S

Purity: 98.00 - 102.0 % (anhydrous basis)

Color and Shape: White or almost white crystalline powder

Molecular weight: 341.43

Ref: 7W-GP7278

Sulpiride

CAS: 15676-16-1

Formula: C₁₅H₂₃N₃O₄S

Color and Shape: White To Off-White Solid

Molecular weight: 341.43

Ref: 4Z-S-4011

Sulpiride, EP grade

CAS: 15676-16-1

Formula: C₁₅H₂₃N₃O₄S

Purity: 98.5 - 101.0 % (dried substance)

Color and Shape: White or almost white crystalline powder

Molecular weight: 341.43

Ref: 7W-GP2409

Sulpiride 1.0 mg/ml in Methanol

CAS: 15676-16-1

Color and Shape: Single Solution

Ref: 61-AMP0051.00-01

Sulpiride

CAS: 15676-16-1

Color and Shape: Neat

Ref: 86-MM0051.00

(±)-Sulpiride

CAS: 15676-16-1

Formula: C₁₅H₂₃N₃O₄S

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 341.43

Ref: 3B-S0501

Sulpiride

CAS: 15676-16-1

Formula: C₁₅H₂₃N₃O₄S

Color and Shape: Neat

Molecular weight: 341.43

Ref: 04-C17026900

Sulpiride

CAS: 15676-16-1

Formula: C₁₅H₂₃N₃O₄S

Molecular weight: 341.43

Ref: ST-EA-CP-S64000

rac Sulpiride

Controlled Product

CAS: 15676-16-1

Applications An antipsychotic drug used in the treatment of Schozophrenia and depression.
References Kramer, P., et al.: J. Neurosci., 31, 126 (2011), Alelyunas, Y., et al.: Bioorg. Med. Chem. Lett., 20, 7312, (2010),

Formula: C₁₅H₂₃N₃O₄S

Color and Shape: Neat

Molecular weight: 341.43

Ref: TR-S689145

(+/-)-Sulpiride

Controlled Product

CAS: 15676-16-1

Dopamine (D2) receptor antagonist; anti-psychotic; anti-depressant

Formula: C₁₅H₂₃N₃O₄S

Purity: Min. 98 Area-%

Color and Shape: White Off-White Powder

Molecular weight: 341.43 g/mol

Ref: 3D-FS27973

SULPIRIDE

CAS: 15676-16-1

Purity: 98%

Molecular weight: 341.4299927

Ref: 10-F822253