CAS 15687-41-9

(-)-Oxyfedrine

Description:

(-)-Oxyfedrine, with the CAS number 15687-41-9, is a chiral compound that belongs to the class of phenethylamines. It is primarily recognized for its sympathomimetic properties, which means it can mimic the effects of the sympathetic nervous system. This compound is often studied for its potential applications in treating conditions such as hypotension and bronchial asthma due to its ability to stimulate adrenergic receptors. (-)-Oxyfedrine is characterized by its stereochemistry, which contributes to its biological activity and pharmacological effects. The compound typically appears as a white to off-white crystalline solid and is soluble in water and organic solvents, making it versatile for various formulations. Its mechanism of action involves the release of norepinephrine, leading to increased heart rate and bronchodilation. As with many sympathomimetics, careful consideration of dosage and potential side effects is essential in therapeutic contexts. Overall, (-)-Oxyfedrine represents an important compound in medicinal chemistry with specific applications in cardiovascular and respiratory health.

Formula: C₁₉H₂₃NO₃

InChI: InChI=1S/C19H23NO3/c1-14(19(22)15-7-4-3-5-8-15)20-12-11-18(21)16-9-6-10-17(13-16)23-2/h3-10,13-14,19-20,22H,11-12H2,1-2H3/t14-,19-/m0/s1

InChI key: InChIKey=GDYUVHBMFVMBAF-LIRRHRJNSA-N

SMILES: C(CCN[C@H]([C@H](O)C1=CC=CC=C1)C)(=O)C2=CC(OC)=CC=C2

Synonyms:

• 1-Propanone, 3-((2-hydroxy-1-methyl-2-phenylethyl)amino)-1-(3-methoxyphenyl)-, (R*,S*)-(+-)-
• 1-Propanone, 3-[(2-hydroxy-1-methyl-2-phenylethyl)amino]-1-(3-methoxyphenyl)-, [R-(R*,S*)]-
• 1-Propanone, 3-[[(1S,2R)-2-hydroxy-1-methyl-2-phenylethyl]amino]-1-(3-methoxyphenyl)-
• 3-[(1-Hydroxy-1-Phenylpropan-2-Yl)Amino]-1-(3-Methoxyphenyl)Propan-1-One
• 3-[[(1S,2R)-2-Hydroxy-1-methyl-2-phenylethyl]amino]-1-(3-methoxyphenyl)-1-propanone
• 3-{[(1S,2R)-2-hydroxy-1-methyl-2-phenylethyl]amino}-1-(3-methoxyphenyl)propan-1-one
• <span class="text-smallcaps">L</span>-(1-Hydroxy-1-phenyl-2-propylamino)-1-(m-methoxyphenyl)-1-propanone
• <span class="text-smallcaps">L</span>-3-[(β-Hydroxy-α-methylphenethyl)amino]-3′-methoxypropiophenone
• DL-3-((beta-Hydroxy-alpha-methylphenethyl)amino)-3'-methoxy-propiophenone
• Oxyfedrin
• Oxyphedrine
• Oxyfedrine

Oxyfedrine

CAS: 15687-41-9

Oxyfedrine is a non-selective enzyme inhibitor that inhibits protein synthesis in the heart. It has been shown to inhibit cardiac enzymes, such as papillary muscle, and to have potential as a biomarker for infectious diseases and autoimmune diseases. Oxyfedrine also causes cardiac effects such as congestive heart failure, myocardial infarction, or cardiogenic shock. The drug is used orally and can be administered intravenously. Oxyfedrine may be used to treat chronic oral infections with anaerobic bacteria caused by pyrazole-containing organisms. Sodium citrate is often co-administered with oxyfedrine because it prevents renal toxicity due to the accumulation of citric acid in the blood stream.

Formula: C₁₉H₂₃NO₃

Purity: Min. 95 Area-%

Color and Shape: Powder

Molecular weight: 313.39 g/mol

Ref: 3D-FO170117

Oxyfedrine

Controlled Product

CAS: 15687-41-9

Stability Moisture Sensitive
Applications Oxyfedrine acts as a vasodilator affecting the coronary base flow.
References Baraka, Y. et al.: J. Drug Res., 12, 161 (1980);

Formula: C₁₉H₂₃NO₃

Color and Shape: Neat

Molecular weight: 313.39

Ref: TR-O870700

Oxyfedrine

CAS: 15687-41-9

Oxyfedrine: oral β-adrenoreceptor agonist, vasodilator for cardiovascular research.

Formula: C₁₉H₂₃NO₃

Color and Shape: Solid

Molecular weight: 313.39

Ref: TM-T60795