CAS 15883-20-2

2′,6′-Pipecoloxylidide

Description:

2′,6′-Pipecoloxylidide, with the CAS number 15883-20-2, is a chemical compound that belongs to the class of local anesthetics. It is characterized by its structural features, which include a pipecolic acid derivative and a substituted aromatic ring, contributing to its pharmacological properties. This compound exhibits a relatively high lipophilicity, which enhances its ability to penetrate biological membranes, making it effective in blocking nerve conduction. Its mechanism of action involves the inhibition of voltage-gated sodium channels, leading to a decrease in neuronal excitability and pain sensation. Additionally, 2′,6′-Pipecoloxylidide is known for its relatively low toxicity profile compared to other local anesthetics, making it a candidate for various medical applications. The compound is typically administered via injection and is used in procedures requiring localized pain relief. As with all anesthetics, careful consideration of dosage and potential side effects is essential for safe and effective use in clinical settings.

Formula: C₁₄H₂₀N₂O

InChI: InChI=1S/C14H20N2O/c1-10-6-5-7-11(2)13(10)16-14(17)12-8-3-4-9-15-12/h5-7,12,15H,3-4,8-9H2,1-2H3,(H,16,17)

InChI key: InChIKey=SILRCGDPZGQJOQ-UHFFFAOYSA-N

SMILES: N(C(=O)C1CCCCN1)C2=C(C)C=CC=C2C

Synonyms:

• 2',6'-Pipecolinoxylidide
• 2',6'-Pipecoloxylidide
• 2,6-Pipecoloxylidide
• 2-Pipecolinoxylidide
• 2-Piperidinecarboxamide, N-(2,6-dimethylphenyl)-
• 2′,6′-Pipecolylxylidine
• Debutylbupivacaine
• Desbutylbupivacaine
• N-(2',6'-dimethylphenyl)-piperidine-2-carboxylic amide
• N-(2,6-Dimethylphenyl)-2-piperidinecarboxamide
• N-(2,6-dimethylphenyl)piperidine-2-carboxamide
• N-Desbutylbupivacaine

N-(2,6-Dimethylphenyl)piperidine-2-carboxamide

CAS: 15883-20-2

Formula: C₁₄H₂₀N₂O

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 232.33

Ref: 3B-D4348

debutylbupivacaine

CAS: 15883-20-2

Debutylbupivacaine is the intermediate of ropivacaine hydrochloride and bupivacaine.

Formula: C₁₄H₂₀N₂O

Purity: 99.50%

Color and Shape: Off-White To Light Yellow Powder

Molecular weight: 232.32

Ref: TM-T1697

2',6'-Pipecoloxylidide

CAS: 15883-20-2

Formula: C₁₄H₂₀N₂O

Purity: 98%

Color and Shape: Solid

Molecular weight: 232.3214

Ref: IN-DA001QWL

Bupivacaine EP Impurity B-d6 (Bupivacaine USP Related Compound B-d6 (Free Form))

CAS: 15883-20-2

Formula: C₁₄H₁₄D₆N₂O

Color and Shape: White To Off-White Solid

Molecular weight: 238.36

Ref: 4Z-B-0612

N-(2,6-Dimethylphenyl)piperidine-2-carboxamide

CAS: 15883-20-2

N-(2,6-Dimethylphenyl)piperidine-2-carboxamide

Purity: ≥95%

Color and Shape: Solid

Molecular weight: 232.32g/mol

Ref: 54-OR3403

debutylbupivacaine

CAS: 15883-20-2

debutylbupivacaine

Purity: ≥98%

Molecular weight: 232.32g/mol

Ref: 54-BUP11358

Bupivacaine EP Impurity B (Bupivacaine USP Related Compound B (Free Form))

CAS: 15883-20-2

Formula: C₁₄H₂₀N₂O

Color and Shape: White To Off-White Solid

Molecular weight: 232.33

Ref: 4Z-B-066

(RS)-N-(2,6-Dimethylphenyl)piperidine-2-carboxamide

Controlled Product

CAS: 15883-20-2

Formula: C₁₄H₂₀N₂O

Color and Shape: Neat

Molecular weight: 232.32

Ref: 86-MM0368.08

Bupivacaine EP Impurity B

CAS: 15883-20-2

Formula: C₁₄H₂₀N₂O

Molecular weight: 232.33

Ref: ST-EA-CP-B20002

N-Desbutyl Bupivacaine

Controlled Product

CAS: 15883-20-2

Impurity Bupivacaine USP Related Compound B
Applications N-Desbutyl Bupivacaine (Bupivacaine USP Related Compound B) is a major metabolite of Bupivacaine.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Bargetzi, M.J., et al.: Clin. Pharmacol. Ther., 46, 521 (1989), Shimada, T., et al.: J. Pharmacol. Exp. Ther., 270, 414 (1994), Attolini, L., et al.: Fundam. Clin. Pharmacol., 11, 152 (1997),

Formula: C₁₄H₂₀N₂O

Color and Shape: White To Light Beige

Molecular weight: 232.32

Ref: TR-D288785

N-Desbutyl bupivacaine

CAS: 15883-20-2

N-Desbutyl bupivacaine is a local anaesthetic that is metabolized by the human body to produce bupivacaine. It has been shown to be effective in the treatment of pain. N-Desbutyl bupivacaine binds to the α1-acid glycoprotein, which decreases its clearance from the blood and prolongs its duration of action. This agent is metabolized by the liver into an active form, which has been shown to be effective in inhibiting pain. The plasma concentration of N-Desbutyl bupivacaine can be measured using liquid chromatography, with a kinetic study showing that it takes about 1 hour for this agent to reach peak levels in serum. The effective dose for N-Desbutyl bupivacaine is typically 2 mg/kg, although this may vary based on individual factors such as weight and age.

Formula: C₁₄H₂₀N₂O

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 232.32 g/mol

Ref: 3D-FD21147

N-(2,6-Dimethylphenyl)piperidine-2-carboxamide

CAS: 15883-20-2

Formula: C₁₄H₂₀N₂O

Purity: 95%

Color and Shape: Solid

Molecular weight: 232.327

Ref: 10-F076146

N-Desbutyl Bupivacaine-d6

Controlled Product

CAS: 15883-20-2

Formula: C₁₄H₁₄D₆N₂O

Color and Shape: Neat

Molecular weight: 238.36

Ref: TR-D288787

N-Desbutylbupivacaine (N-Desmethylmepivacaine)

CAS: 15883-20-2

Color and Shape: Neat

Ref: 61-FOR0368.08