CAS 15883-20-2
:2′,6′-Pipecoloxylidide
Description:
2′,6′-Pipecoloxylidide, with the CAS number 15883-20-2, is a chemical compound that belongs to the class of local anesthetics. It is characterized by its structural features, which include a pipecolic acid derivative and a substituted aromatic ring, contributing to its pharmacological properties. This compound exhibits a relatively high lipophilicity, which enhances its ability to penetrate biological membranes, making it effective in blocking nerve conduction. Its mechanism of action involves the inhibition of voltage-gated sodium channels, leading to a decrease in neuronal excitability and pain sensation. Additionally, 2′,6′-Pipecoloxylidide is known for its relatively low toxicity profile compared to other local anesthetics, making it a candidate for various medical applications. The compound is typically administered via injection and is used in procedures requiring localized pain relief. As with all anesthetics, careful consideration of dosage and potential side effects is essential for safe and effective use in clinical settings.
Formula:C14H20N2O
InChI:InChI=1S/C14H20N2O/c1-10-6-5-7-11(2)13(10)16-14(17)12-8-3-4-9-15-12/h5-7,12,15H,3-4,8-9H2,1-2H3,(H,16,17)
InChI key:InChIKey=SILRCGDPZGQJOQ-UHFFFAOYSA-N
SMILES:N(C(=O)C1CCCCN1)C2=C(C)C=CC=C2C
Synonyms:- 2',6'-Pipecolinoxylidide
- 2',6'-Pipecoloxylidide
- 2,6-Pipecoloxylidide
- 2-Pipecolinoxylidide
- 2-Piperidinecarboxamide, N-(2,6-dimethylphenyl)-
- 2′,6′-Pipecolylxylidine
- Debutylbupivacaine
- Desbutylbupivacaine
- N-(2',6'-dimethylphenyl)-piperidine-2-carboxylic amide
- N-(2,6-Dimethylphenyl)-2-piperidinecarboxamide
- N-(2,6-dimethylphenyl)piperidine-2-carboxamide
- N-Desbutylbupivacaine
- See more synonyms
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Found 15 products.
N-(2,6-Dimethylphenyl)piperidine-2-carboxamide
CAS:Formula:C14H20N2OPurity:>98.0%(HPLC)(T)Color and Shape:White to Almost white powder to crystalMolecular weight:232.33N-(2',6'-Dimethylphenyl)-2-piperidinecarboxamide
CAS:Formula:C14H20N2OPurity:96%Color and Shape:SolidMolecular weight:232.3214debutylbupivacaine
CAS:Debutylbupivacaine is the intermediate of ropivacaine hydrochloride and bupivacaine.Formula:C14H20N2OPurity:99.50%Color and Shape:Off-White To Light Yellow PowderMolecular weight:232.32N-(2,6-Dimethylphenyl)piperidine-2-carboxamide
CAS:N-(2,6-Dimethylphenyl)piperidine-2-carboxamideFormula:C14H20N2OPurity:≥95%Color and Shape:SolidMolecular weight:232.3214Bupivacaine EP Impurity B-d6 (Bupivacaine USP Related Compound B-d6 (Free Form))
CAS:Formula:C14H14D6N2OColor and Shape:White To Off-White SolidMolecular weight:238.36Bupivacaine EP Impurity B (Bupivacaine USP Related Compound B (Free Form))
CAS:Formula:C14H20N2OColor and Shape:White To Off-White SolidMolecular weight:232.33(RS)-N-(2,6-Dimethylphenyl)piperidine-2-carboxamide
CAS:Controlled ProductFormula:C14H20N2OColor and Shape:NeatMolecular weight:232.32N-Desbutyl Bupivacaine
CAS:Controlled ProductImpurity Bupivacaine USP Related Compound B
Applications N-Desbutyl Bupivacaine (Bupivacaine USP Related Compound B) is a major metabolite of Bupivacaine.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Bargetzi, M.J., et al.: Clin. Pharmacol. Ther., 46, 521 (1989), Shimada, T., et al.: J. Pharmacol. Exp. Ther., 270, 414 (1994), Attolini, L., et al.: Fundam. Clin. Pharmacol., 11, 152 (1997),Formula:C14H20N2OColor and Shape:NeatMolecular weight:232.32N-Desbutyl Bupivacaine-d6
CAS:Controlled ProductFormula:C14H14D6N2OColor and Shape:NeatMolecular weight:238.36N-Desbutyl bupivacaine
CAS:N-Desbutyl bupivacaine is a local anaesthetic that is metabolized by the human body to produce bupivacaine. It has been shown to be effective in the treatment of pain. N-Desbutyl bupivacaine binds to the α1-acid glycoprotein, which decreases its clearance from the blood and prolongs its duration of action. This agent is metabolized by the liver into an active form, which has been shown to be effective in inhibiting pain. The plasma concentration of N-Desbutyl bupivacaine can be measured using liquid chromatography, with a kinetic study showing that it takes about 1 hour for this agent to reach peak levels in serum. The effective dose for N-Desbutyl bupivacaine is typically 2 mg/kg, although this may vary based on individual factors such as weight and age.Formula:C14H20N2OPurity:Min. 98 Area-%Color and Shape:PowderMolecular weight:232.32 g/molN-(2,6-Dimethylphenyl)piperidine-2-carboxamide
CAS:Formula:C14H20N2OPurity:95%Color and Shape:SolidMolecular weight:232.327Desbutylbupivacaine
CAS:N-(2',6'-Dimethylphenyl)-2-piperidinecarboxamideFormula:C14H20N2OPurity:96%Molecular weight:232.32
