CAS 15917-65-4: N-Desmethyl Tamoxifen Hydrochloride

Description:N-Desmethyl Tamoxifen Hydrochloride, with the CAS number 15917-65-4, is a derivative of the selective estrogen receptor modulator (SERM) tamoxifen. It is characterized by its role as an active metabolite of tamoxifen, which is primarily used in the treatment of estrogen receptor-positive breast cancer. This compound exhibits anti-estrogenic properties, particularly in breast tissue, while displaying estrogenic effects in other tissues, such as bone and endometrium. N-Desmethyl Tamoxifen Hydrochloride is typically a white to off-white crystalline powder, soluble in organic solvents like ethanol and dimethyl sulfoxide (DMSO), but has limited solubility in water. Its pharmacokinetics involve metabolism primarily in the liver, where it undergoes further biotransformation. The compound's efficacy and safety profile make it a subject of interest in both clinical and research settings, particularly in understanding resistance mechanisms in breast cancer therapy. As with any pharmaceutical agent, its use should be guided by appropriate medical advice and regulatory standards.

Formula:C₂₅H₂₈ClNO

InChI:InChI=1/C25H27NO.ClH/c1-3-24(20-10-6-4-7-11-20)25(21-12-8-5-9-13-21)22-14-16-23(17-15-22)27-19-18-26-2;/h4-17,26H,3,18-19H2,1-2H3;1H/b25-24-;

Synonyms:
N-Demethyltamoxifen Hydrochlorid
(Z)-2-[4-(1,2-Diphenyl-1-butenyl)phenoxy]-N-methylethanamine Hydrochloride
2-{4-[(1E)-1,2-diphenylbut-1-en-1-yl]phenoxy}-N-methylethanamine
2-[4-[(Z)-1,2-diphenylbut-1-enyl]phenoxy]-N-methyl-ethanamine hydrochloride

Found 9 products.

Product data	Purity	Price range	Estimated delivery
N-Desmethyltamoxifen hydrochloride REF: TM-T12148CAS: 15917-65-4	99.15%	35.00 €~1,074.00 €	Wed 09 Apr 25
Ethanamine, 2-[4-[(1Z)-1,2-diphenyl-1-buten-1-yl]phenoxy]-N-methyl-, hydrochloride (1:1) REF: IN-DA001QJICAS: 15917-65-4	98%	To inquire	Wed 09 Apr 25
N-Desmethyltamoxifen hydrochloride REF: 7W-GK5368CAS: 15917-65-4	- - -	To inquire	Thu 10 Apr 25
Tamoxifen EP Impurity F HCl REF: 4Z-T-011CAS: 15917-65-4	- - -	To inquire	Thu 10 Apr 25
N-Desmethyltamoxifen (hydrochloride) REF: 10-F986646CAS: 15917-65-4	- - -	104.00 €~1,536.00 €	Mon 14 Apr 25
Tamoxifen Citrate EP Impurity F (as Hydrochloride) REF: 86-MM0053.12CAS: 15917-65-4	- - -	To inquire	Mon 14 Apr 25
Tamoxifen EP Impurity C REF: 4Z-T-0115CAS: 15917-65-4	- - -	To inquire	Wed 16 Apr 25
N-Desmethyl Tamoxifen Hydrochloride REF: TR-D293900CAS: 15917-65-4	- - -	369.00 €~1,411.00 €	Mon 21 Apr 25
N-Desmethyl tamoxifen hydrochloride REF: 3D-FD21327CAS: 15917-65-4	Min. 95%	143.00 €~755.00 €	Wed 04 Jun 25