CAS 15958-92-6

bradykinin fragment 1-8

Description:

Bradykinin fragment 1-8, also known as BK(1-8), is a peptide derived from the larger bradykinin molecule, which is a potent vasodilator involved in various physiological processes, including inflammation and pain response. This fragment consists of the first eight amino acids of bradykinin, specifically the sequence Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe. It retains some biological activity, influencing vascular permeability and modulating pain sensation. The CAS number 15958-92-6 uniquely identifies this compound in chemical databases. Bradykinin fragment 1-8 is typically characterized by its relatively small size, hydrophilic nature, and ability to interact with specific receptors in the body, such as the bradykinin B2 receptor. Its role in physiological processes makes it a subject of interest in pharmacological research, particularly in the context of cardiovascular health and pain management. Additionally, due to its peptide nature, it may be sensitive to enzymatic degradation, which can affect its stability and bioavailability in therapeutic applications.

Formula: C₄₄H₆₁N₁₁O₁₀

InChI: InChI=1/C44H61N11O10/c45-29(15-7-19-48-44(46)47)40(61)55-22-10-18-35(55)42(63)54-21-8-16-33(54)38(59)49-25-36(57)50-30(23-27-11-3-1-4-12-27)37(58)52-32(26-56)41(62)53-20-9-17-34(53)39(60)51-31(43(64)65)24-28-13-5-2-6-14-28/h1-6,11-14,29-35,56H,7-10,15-26,45H2,(H,49,59)(H,50,57)(H,51,60)(H,52,58)(H,64,65)(H4,46,47,48)/t29-,30-,31-,32-,33-,34-,35-/m0/s1

SMILES: c1ccc(cc1)C[C@@H](C(=N[C@@H](CO)C(=O)N1CCC[C@H]1C(=N[C@@H](Cc1ccccc1)C(=O)O)O)O)N=C(CN=C([C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(=N)N)N)O)O

Synonyms:

• (Des-Arg9)-Bradykinin
• H-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-OH
• N~5~-(diaminomethylidene)-L-ornithyl-L-prolyl-L-prolylglycyl-L-phenylalanyl-L-seryl-L-prolyl-L-phenylalanine

(Des-Arg⁹)-Bradykinin

CAS: 15958-92-6

Bradykinin 2-9, an often-used calibration standard in mass spectrometry.

Formula: C₄₄H₆₁N₁₁O₁₀

Purity: 98.9%

Color and Shape: Whitish Lyophilisate

Molecular weight: 904.04

Ref: 01-4006675

[Des-Arg9]-Bradykinin

CAS: 15958-92-6

Formula: C₄₄H₆₁N₁₁O₁₀

Purity: 95%

Color and Shape: Solid

Molecular weight: 904.0228

Ref: IN-DA01E2GE

[Des-Arg9]-Bradykinin

CAS: 15958-92-6

[Des-Arg9]-Bradykinin ([Des-Arg9]-Bradykinin(2TFA))(2TFA) is an agonist of Bradykinin (B1) receptor.

Formula: C₄₄H₆₁N₁₁O₁₀

Purity: 98%

Color and Shape: Solid

Molecular weight: 904.02

Ref: TM-T7645

Bradykinin 1-8 acetate salt hydrate

CAS: 15958-92-6

Molecular weight: 904.02 (anhydrous)

Ref: 7W-GM7175

[Des-Arg9]-Bradykinin

CAS: 15958-92-6

Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool

Formula: C₄₄H₆₁N₁₁O₁₀

Molecular weight: 904.04 g/mol

Ref: 3D-PP50709

Des-Arg9-Bradykinin

CAS: 15958-92-6

Des-Arg9-bradykinin is a peptide that is a potent activator of the B2 receptor. It is a potent inhibitor of ion channels, including Ca2+, K+ and Na+ channels. Des-Arg9-bradykinin has been used as a research tool in cell biology, particularly to investigate the role of bradykinins in signal transduction pathways. This chemical is highly purified and can be obtained from Sigma-Aldrich with CAS No. 15958-92-6.

Formula: C₄₄H₆₁N₁₁O₁₀

Purity: Min. 95%

Molecular weight: 904.02 g/mol

Ref: 3D-PBK-4067-V