CAS 1610022-76-8

Formula: C21H22ClN3O2

InChI: InChI=1S/C21H22ClN3O2/c1-21(2,3)16-8-4-14(5-9-16)13-25-19(20(26)24-27)12-18(23-25)15-6-10-17(22)11-7-15/h4-12,27H,13H2,1-3H3,(H,24,26)

InChI key: ZFDMUUNGVLREEC-UHFFFAOYSA-N

SMILES: CC(C)(C)C1=CC=C(C=C1)CN2C(=CC(=N2)C3=CC=C(C=C3)Cl)C(=O)NO

Nrf2-IN-1

CAS: 1610022-76-8

Nrf2-IN-1

Formula: C₂₁H₂₂ClN₃O₂

Purity: ≥95%

Molecular weight: 383.87

Ref: 54-BUP08519

Nrf2-IN-1

CAS: 1610022-76-8

Nrf2-IN-1 is an nuclear factor-erythroid 2-related factor 2 (Nrf2) inhibitor. Nrf2-IN-1 is developed for the research of acute myeloid leukemia (AML).

Formula: C₂₁H₂₂ClN₃O₂

Purity: 95.00% - 99.68%

Color and Shape: Solid

Molecular weight: 383.871

Ref: TM-T12253

3-(4-Chlorophenyl)-1-[[4-(1,1-dimethylethyl)phenyl]methyl]-N-hydroxy-1H-pyrazole-5-carboxamide

CAS: 1610022-76-8

Formula: C₂₁H₂₂ClN₃O₂

Purity: 99.89%

Molecular weight: 383.8713

Ref: IN-DA003AF0

Nrf2-IN-1

CAS: 1610022-76-8

Nrf2-IN-1 is a small molecule that has been shown to increase the glomerular filtration rate in rats. It also enhances renal function by reducing urea nitrogen and staining. In addition, Nrf2-IN-1 protects against renal injury caused by ischemia reperfusion injury in rats. Nrf2-IN-1 also prevents oxidative injury of kidney cells and reduces cell apoptosis. This drug has been shown to reduce inflammation by inhibiting tumor necrosis factor α (TNFα) production in mice with acute kidney injury.

Formula: C₂₁H₂₂ClN₃O₂

Purity: Min. 95%

Molecular weight: 383.9 g/mol

Ref: 3D-KPC02276