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CAS 161125-36-6

:

3-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-2-hydroxypropanoic acid

Description:
3-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-2-hydroxypropanoic acid, commonly referred to as Fmoc-Ser(OH)-OH, is an amino acid derivative characterized by the presence of a fluorene moiety, which provides stability and protection for the amino group during peptide synthesis. This compound features a hydroxyl group on the second carbon of the propanoic acid chain, contributing to its classification as a serine derivative. The Fmoc (fluorenylmethyloxycarbonyl) group is a widely used protecting group in peptide chemistry, allowing for selective deprotection under mild conditions. The presence of the hydroxyl group also imparts hydrophilicity, influencing its solubility in polar solvents. This compound is typically utilized in solid-phase peptide synthesis and plays a crucial role in the formation of peptides and proteins. Its structure allows for specific interactions in biological systems, making it valuable in research and pharmaceutical applications. Overall, its unique characteristics make it an important building block in the field of organic and medicinal chemistry.
Formula:C18H17NO5
InChI:InChI=1S/C18H17NO5/c20-16(17(21)22)9-19-18(23)24-10-15-13-7-3-1-5-11(13)12-6-2-4-8-14(12)15/h1-8,15-16,20H,9-10H2,(H,19,23)(H,21,22)
InChI key:InChIKey=OOFCRVWLJFLVCB-UHFFFAOYSA-N
SMILES:C(OC(NCC(C(O)=O)O)=O)C1C=2C(C=3C1=CC=CC3)=CC=CC2
Synonyms:
  • 3-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-2-hydroxypropanoic acid
  • Fmoc-3-amino-2-hydroxypropionic acid
  • Propanoic acid, 3-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-2-hydroxy-
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