CAS 16156-58-4

PROPARGYL METHANESULFONATE ESTER, 95

Description:

Propargyl methanesulfonate ester, with the CAS number 16156-58-4, is an organic compound characterized by the presence of a propargyl group (an alkyne functional group) attached to a methanesulfonate moiety. This compound typically appears as a colorless to pale yellow liquid and is known for its reactivity, particularly in nucleophilic substitution reactions due to the presence of the sulfonate group, which is a good leaving group. It is often utilized in organic synthesis, especially in the preparation of various derivatives and in the formation of carbon-carbon bonds. The compound is also recognized for its potential applications in medicinal chemistry and materials science. However, it should be handled with care, as it may pose health hazards, including irritation to the skin and eyes, and it may be harmful if inhaled or ingested. Proper safety protocols, including the use of personal protective equipment, are essential when working with this substance in a laboratory setting.

Formula: C₄H₆O₃S

InChI: InChI=1/C4H6O3S/c1-3-4-7-8(2,5)6/h1H,4H2,2H3

SMILES: C#CCOS(=O)(=O)C

Synonyms:

• 2-Propyn-1-ol,methanesulfonate
• 2-Propynyl Methanesulfonate
• Methanesulfonic Acid Prop-2-Ynyl Ester
• Propargyl Mesylate
• Propargyl Methylsulfonate
• Prop-2-Yn-1-Yl Methanesulfonate

2-Propyn-1-yl Methanesulfonate

CAS: 16156-58-4

Formula: C₄H₆O₃S

Purity: >98.0%(GC)

Color and Shape: Colorless to Almost colorlessclear liquid

Molecular weight: 134.15

Ref: 3B-P3022

2-Propyn-1-ol, 1-methanesulfonate

CAS: 16156-58-4

Formula: C₄H₆O₃S

Purity: 97%

Color and Shape: Liquid

Molecular weight: 134.1536

Ref: IN-DA001VPF

Propargyl methanesulfonate ester

CAS: 16156-58-4

Propargyl methanesulfonate ester

Purity: 99%

Molecular weight: 134.15g/mol

Ref: 54-OR95277

Propargyl Methanesulfonate Ester, 95%

Controlled Product

CAS: 16156-58-4

Formula: C₄H₆O₃S

Purity: 95%

Color and Shape: Neat

Molecular weight: 134.15

Ref: TR-P766000

Propargyl methanesulfonate ester

CAS: 16156-58-4

Propargyl methanesulfonate ester is an organic compound that is used as a cross-coupling reagent in the synthesis of chiral mesylates. It is prepared by treatment of propargyl alcohol with methanesulfonyl chloride and sodium hydroxide in an organic solvent. The product is purified by removal of the solvent, followed by crystallization or distillation. The mesylate group reacts with an amine to give a secondary amine, which can be converted to a carbamate or mediated reaction product. This process can also generate genotoxic impurities, such as dioxane and 1,4-dioxane, which are removed by transfer to an inert solvent.

Formula: C₄H₆O₃S

Purity: Min. 95%

Color and Shape: Clear Liquid

Molecular weight: 134.15 g/mol

Ref: 3D-FP27194

Propargyl methanesulfonate ester

CAS: 16156-58-4

Formula: C₄H₆O₃S

Purity: 97%

Molecular weight: 134.15

Ref: 10-F549686