CAS 161796-78-7

Esomeprazole sodium

Description:

Esomeprazole sodium is a proton pump inhibitor (PPI) primarily used to treat gastroesophageal reflux disease (GERD) and other conditions associated with excessive stomach acid production. It is the S-enantiomer of omeprazole, which enhances its efficacy and bioavailability. This compound is typically presented as a sodium salt, which improves its solubility in aqueous solutions. Esomeprazole sodium works by irreversibly inhibiting the H+/K+ ATPase enzyme in the gastric parietal cells, leading to a significant reduction in gastric acid secretion. It is characterized by its white to off-white crystalline powder form, with a molecular formula that includes carbon, hydrogen, nitrogen, oxygen, and sodium. The substance is generally stable under normal conditions but should be stored away from moisture and light to maintain its potency. Commonly administered in oral form, esomeprazole sodium is well-absorbed in the gastrointestinal tract, with peak plasma concentrations occurring within a few hours post-administration. Its pharmacokinetics can be influenced by factors such as food intake and individual metabolic variations.

Formula: C₁₇H₁₉N₃O₃S·Na

InChI: InChI=1S/C17H19N3O3S.Na/c1-10-8-18-15(11(2)16(10)23-4)9-24(21)17-19-13-6-5-12(22-3)7-14(13)20-17;/h5-8H,9H2,1-4H3,(H,19,20);/t24-;/m0./s1

InChI key: InChIKey=HVAJOLFRLWQQQL-JIDHJSLPSA-N

SMILES: S(CC1=C(C)C(OC)=C(C)C=N1)(=O)C=2NC=3C(N2)=CC=C(OC)C3.[Na]

Synonyms:

• (S)-5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole sodium salt
• (S)-Omeprazole sodium
• 1H-Benzimidazole, 5-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-, sodium salt
• 1H-Benzimidazole, 5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-, sodium salt, (S)-
• 1H-Benzimidazole, 6-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-, sodium salt (1:1)
• 1H-benzimidazole, 5-Methoxy-2-[[(4-Methoxy-3,5-dimethyl-2-PYRIDINYL)methyl]sulfinyl]-, sodium salt
• 5-Methoxy-2-((S)-((4-methoxy-3,5-dimethyl-2-pyridyl)methyl)sulfinyl-1H-benzimidazole sodium salt
• Bis[5-Methoxy-2-[(4-Methoxy-3,5-Dimethyl-2-Pyridyl)Methylsulfinyl]Benzimidazol-1-Yl]Magnesium
• Esomeprazole Na
• Esomeprazole sodium salt
• Esomeprazoleandsalts
• H 199/18 sodium
• Sodium 5-Methoxy-2-{[(4-Methoxy-3,5-Dimethylpyridin-2-Yl)Methyl]Sulfinyl}Benzimidazol-1-Ide
• sodium 5-methoxy-2-{(S)-[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-2,3-dihydrobenzimidazol-1-ide

Esomeprazole Sodium

CAS: 161796-78-7

Color and Shape: Neat

Ref: 61-FOR3373.00

ESOMEPRAZOLE SODIUM CRS

CAS: 161796-78-7

ESOMEPRAZOLE SODIUM CRS

Color and Shape: Added Added

Ref: 41-Y0002075

Esomeprazole Sodium

CAS: 161796-78-7

Compounds containing an unfused pyridine ring in the structure, nesoi

Formula: C₁₇H₁₈N₃NaO₃S

Color and Shape: White Off-White Powder

Molecular weight: 367.09666

Ref: 45-1249790

1H-Benzimidazole, 6-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-, sodium salt (1:1)

CAS: 161796-78-7

Formula: C₁₇H₁₈N₃NaO₃S

Purity: %

Color and Shape: Solid

Molecular weight: 367.3979

Ref: IN-DA001VVZ

Esomeprazole Sodium

CAS: 161796-78-7

Esomeprazole Sodium

Purity: ≥98%

Molecular weight: 367.4g/mol

Ref: 54-BUP10558

Esomeprazole sodium salt hydrate

CAS: 161796-78-7

Formula: C₁₇H₁₈N₃NaO₃S

Purity: (Titration) ≥ 98.0%

Color and Shape: White to off-white or pale yellow crystalline powder

Molecular weight: 367.40

Ref: 7W-GP5980

Esomeprazole Sodium Salt

CAS: 161796-78-7

Formula: C₁₇H₁₈N₃O₃S·Na

Color and Shape: White To Off-White Solid

Molecular weight: 344.42 22.99

Ref: 4Z-O-029

Esomeprazole Sodium

CAS: 161796-78-7

Formula: C₁₇H₁₈N₃O₃S·Na

Color and Shape: White To Beige Brown

Molecular weight: 367.40

Ref: 86-MM3373.00

(S)-Omeprazole Sodium Salt

CAS: 161796-78-7

Formula: C₁₇H₁₈N₃NaO₃S

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 367.40

Ref: 3B-O0560

Esomeprazole Sodium

CAS: 161796-78-7

Esomeprazole Sodium ((S)-Omeprazole sodium) is the S-isomer of omeprazole with selective and irreversible proton pump inhibitor activity.

Formula: C₁₇H₁₈N₃O₃S·Na

Purity: 98.17% - >99.99%

Color and Shape: Solid

Molecular weight: 367.4

Ref: TM-T2686L

Sodium (S)-6-methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)benzo[d]imidazol-1-ide

CAS: 161796-78-7

Purity: 95.0%

Molecular weight: 367.3999938964844

Ref: 10-F219014

Esomeprazole sodium

CAS: 161796-78-7

Esomeprazole is a proton pump inhibitor used to treat gastroesophageal reflux disease and other conditions where there is too much stomach acid. It is available as a capsule or tablet in doses of 20, 40, and 60 mg. Esomeprazole inhibits the production of gastric acid by blocking the hydrogen/potassium adenosine triphosphate (H+/K+ ATPase) enzyme system at the secretory surface of the gastric parietal cells. Omeprazole is an acidic drug that blocks the H+/K+ ATPase enzyme system. The two drugs have been compared in two-way crossover studies using healthy volunteers who were given omeprazole magnesium for one week followed by esomeprazole sodium for another week. There was no difference in their effect on acid secretion or on heartburn relief. The plasma concentrations of both drugs increased with increasing dose, but there was no significant difference between them in terms of either

Formula: C₁₇H₁₈N₃NaO₃S

Purity: (%) Min. 95%

Color and Shape: Powder

Molecular weight: 367.4 g/mol

Ref: 3D-IM58097

Esomeprazole sodium - EP

CAS: 161796-78-7

Esomeprazole sodium is a proton pump inhibitor that decreases the production of stomach acid. It is used in the treatment of symptoms such as heartburn, regurgitation, and ulcers caused by gastroesophageal reflux disease (GERD). Esomeprazole sodium has been shown to reduce the amount of acid produced in the stomach and to increase the pH level in the stomach. This drug also has significant interactions with other drugs, which can lead to an increased risk of adverse events. Esomeprazole sodium is excreted from the body through urine and feces. The active form of esomeprazole is also found in wastewater treatment plants and can contribute to antimicrobial resistance.

Formula: C₁₇H₁₈N₃NaO₃S

Purity: Min. 95%

Color and Shape: White/Off-White Solid

Molecular weight: 367.4 g/mol

Ref: 3D-IE177087

Esomeprazole Sodium

CAS: 161796-78-7

Formula: C₁₇H₁₉N₃O₃SNa

Molecular weight: 345.4 : 23.0

Ref: ST-EA-CP-E14021