CAS 161796-78-7
:Esomeprazole sodium
Description:
Esomeprazole sodium is a proton pump inhibitor (PPI) primarily used to treat gastroesophageal reflux disease (GERD) and other conditions associated with excessive stomach acid production. It is the S-enantiomer of omeprazole, which enhances its efficacy and bioavailability. This compound is typically presented as a sodium salt, which improves its solubility in aqueous solutions. Esomeprazole sodium works by irreversibly inhibiting the H+/K+ ATPase enzyme in the gastric parietal cells, leading to a significant reduction in gastric acid secretion. It is characterized by its white to off-white crystalline powder form, with a molecular formula that includes carbon, hydrogen, nitrogen, oxygen, and sodium. The substance is generally stable under normal conditions but should be stored away from moisture and light to maintain its potency. Commonly administered in oral form, esomeprazole sodium is well-absorbed in the gastrointestinal tract, with peak plasma concentrations occurring within a few hours post-administration. Its pharmacokinetics can be influenced by factors such as food intake and individual metabolic variations.
Formula:C17H19N3O3S·Na
InChI:InChI=1S/C17H19N3O3S.Na/c1-10-8-18-15(11(2)16(10)23-4)9-24(21)17-19-13-6-5-12(22-3)7-14(13)20-17;/h5-8H,9H2,1-4H3,(H,19,20);/t24-;/m0./s1
InChI key:InChIKey=HVAJOLFRLWQQQL-JIDHJSLPSA-N
SMILES:S(CC1=C(C)C(OC)=C(C)C=N1)(=O)C=2NC=3C(N2)=CC=C(OC)C3.[Na]
Synonyms:- (S)-5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole sodium salt
- (S)-Omeprazole sodium
- 1H-Benzimidazole, 5-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-, sodium salt
- 1H-Benzimidazole, 5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-, sodium salt, (S)-
- 1H-Benzimidazole, 6-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-, sodium salt (1:1)
- 1H-benzimidazole, 5-Methoxy-2-[[(4-Methoxy-3,5-dimethyl-2-PYRIDINYL)methyl]sulfinyl]-, sodium salt
- 5-Methoxy-2-((S)-((4-methoxy-3,5-dimethyl-2-pyridyl)methyl)sulfinyl-1H-benzimidazole sodium salt
- Bis[5-Methoxy-2-[(4-Methoxy-3,5-Dimethyl-2-Pyridyl)Methylsulfinyl]Benzimidazol-1-Yl]Magnesium
- Esomeprazole Na
- Esomeprazole sodium salt
- Esomeprazoleandsalts
- H 199/18 sodium
- Sodium 5-Methoxy-2-{[(4-Methoxy-3,5-Dimethylpyridin-2-Yl)Methyl]Sulfinyl}Benzimidazol-1-Ide
- sodium 5-methoxy-2-{(S)-[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-2,3-dihydrobenzimidazol-1-ide
- See more synonyms
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Found 15 products.
(S)-Omeprazole Sodium Salt
CAS:Formula:C17H18N3NaO3SPurity:>98.0%(HPLC)(T)Color and Shape:White to Light yellow powder to crystalMolecular weight:367.40Esomeprazole Sodium
CAS:Compounds containing an unfused pyridine ring in the structure, nesoiFormula:C17H18N3NaO3SColor and Shape:White Off-White PowderMolecular weight:367.096665-Methoxy-2-((S)-((4-methoxy-3,5-dimethyl-2-pyridyl)methyl)sulfinyl-1H-benzimidazole sodium salt
CAS:Formula:C17H18N3NaO3SPurity:98%Color and Shape:SolidMolecular weight:367.3979Esomeprazole Sodium Salt
CAS:Formula:C17H18N3O3S·NaColor and Shape:White To Off-White SolidMolecular weight:344.42 22.99Esomeprazole sodium salt hydrate
CAS:Formula:C17H18N3NaO3SPurity:(Titration) ≥ 98.0%Color and Shape:White to off-white or pale yellow crystalline powderMolecular weight:367.40Esomeprazole Sodium
CAS:Esomeprazole Sodium ((S)-Omeprazole sodium) is the S-isomer of omeprazole with selective and irreversible proton pump inhibitor activity.Formula:C17H18N3O3S·NaPurity:98.17% - >99.99%Color and Shape:SolidMolecular weight:367.4Esomeprazole sodium
CAS:Esomeprazole is a proton pump inhibitor used to treat gastroesophageal reflux disease and other conditions where there is too much stomach acid. It is available as a capsule or tablet in doses of 20, 40, and 60 mg. Esomeprazole inhibits the production of gastric acid by blocking the hydrogen/potassium adenosine triphosphate (H+/K+ ATPase) enzyme system at the secretory surface of the gastric parietal cells. Omeprazole is an acidic drug that blocks the H+/K+ ATPase enzyme system. The two drugs have been compared in two-way crossover studies using healthy volunteers who were given omeprazole magnesium for one week followed by esomeprazole sodium for another week. There was no difference in their effect on acid secretion or on heartburn relief. The plasma concentrations of both drugs increased with increasing dose, but there was no significant difference between them in terms of either
Formula:C17H18N3NaO3SPurity:(%) Min. 95%Color and Shape:PowderMolecular weight:367.4 g/molEsomeprazole sodium
CAS:Sodium (S)-6-methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)benzo[d]imidazol-1-ideFormula:C17H18N3NaO3SPurity:98%Molecular weight:367.4Sodium (S)-6-methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)benzo[d]imidazol-1-ide
CAS:Formula:C17H18N3NaO3SPurity:95.0%Molecular weight:367.4
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