CAS 161818-04-8

(Pyr³)-Amyloid β-Protein (3-40)

CAS: 161818-04-8

The pyroglutamate-modified amyloid-β peptides derived from Aβ40 and Aβ42 have gained considerable attention as potential key participants in the pathology of Alzheimer’s disease (AD) due to their abundance in AD brain, high aggregation propensity, stability, and cellular toxicity. Aβ40 and 42 can be N-terminally truncated by action of cathepsin B. The cyclization of Glu³ is catalyzed by glutaminyl cyclase. Hence, inhibition of these enzymes could be a therapeutic approach to AD.

Formula: C₁₈₇H₂₈₃N₅₁O₅₃S

Purity: 97.3%

Color and Shape: White

Molecular weight: 4125.68

Ref: 01-4050043

(Pyr 3)-Amyloid b-Protein (3-40) trifluoroacetate salt

CAS: 161818-04-8

Please enquire for more information about (Pyr 3)-Amyloid b-Protein (3-40) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page

Formula: C₁₈₇H₂₈₃N₅₁O₅₃S

Purity: Min. 95%

Molecular weight: 4,125.63 g/mol

Ref: 3D-FP110096