![N-[cis-3-(Methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)cyclobutyl]-1-propanesulfonamide](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fcas-image%2Fthumb-webp%2F299400-n-cis-3-methyl-7h-pyrrolo-23-d-pyrimidin-4-ylamino-cyclobutyl-1-propanesulfonamide.webp&w=3840&q=75)
CAS 1622902-68-4
:N-[cis-3-(Methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)cyclobutyl]-1-propanesulfonamide
Description:
N-[cis-3-(Methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)cyclobutyl]-1-propanesulfonamide is a chemical compound characterized by its complex structure, which includes a cyclobutyl group, a sulfonamide functional group, and a pyrrolopyrimidine moiety. This compound is notable for its potential biological activity, particularly in medicinal chemistry, where it may serve as a lead compound for drug development. The presence of the sulfonamide group often contributes to the compound's solubility and ability to interact with biological targets, such as enzymes or receptors. The methyl group and the specific stereochemistry of the cyclobutyl ring can influence the compound's pharmacokinetic properties, including absorption, distribution, metabolism, and excretion (ADME). Additionally, the pyrrolopyrimidine structure is known for its role in various biological activities, making this compound of interest in the fields of pharmacology and drug design. As with many such compounds, further studies would be necessary to fully elucidate its mechanism of action and therapeutic potential.
Formula:C14H21N5O2S
InChI:InChI=1/C14H21N5O2S/c1-3-6-22(20,21)18-10-7-11(8-10)19(2)14-12-4-5-15-13(12)16-9-17-14/h4-5,9-11,18H,3,6-8H2,1-2H3,(H,15,16,17)/t10-,11+
InChI key:InChIKey=IUEWXNHSKRWHDY-PHIMTYICNA-N
SMILES:N(C)(C1=C2C(NC=C2)=NC=N1)[C@H]3C[C@@H](NS(CCC)(=O)=O)C3
Synonyms:- PF 04965842
- 1-Propanesulfonamide, N-[cis-3-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)cyclobutyl]-
- N-[cis-3-[Methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclobutyl]propane-1-sulfonamide
- Abrocitinib
- N-[cis-3-(Methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)cyclobutyl]-1-propanesulfonamide
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Found 10 products.
N-(Cis-3-(Methyl(7H-Pyrrolo[2,3-D]Pyrimidin-4-Yl)Amino)Cyclobutyl)Propane-1-Sulfonamide
CAS:N-(Cis-3-(Methyl(7H-Pyrrolo[2,3-D]Pyrimidin-4-Yl)Amino)Cyclobutyl)Propane-1-SulfonamideFormula:C14H21N5O2SPurity:98%Molecular weight:323.41(3-fluoro-2-(trifluoromethyl)pyridin-4-yl)methanol
CAS:Formula:C14H21N5O2SPurity:99%Color and Shape:SolidMolecular weight:323.4138Ref: IN-DA01FW8P
5gTo inquire1mg31.00€5mg34.00€10mg40.00€25mg49.00€50mg62.00€100mg66.00€250mg106.00€1g162.00€Abrocitinib
CAS:N-(cis-3-(Methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)cyclobutyl)propane-1-sulfonamideFormula:C14H21N5O2SPurity:99%Molecular weight:323.41Abrocitinib
CAS:Abrocitinib (PF-04965842) (PF-04965842) is a potent, specific and orally-active JAK1 inhibitor (IC50s: 29/803 nM for JAK1/2).Formula:C14H21N5O2SPurity:99.09% - 99.91%Color and Shape:White SolidMolecular weight:323.41PF-04965842
CAS:PF-04965842 is an anti-inflammatory drug that belongs to the class of Jak1 inhibitors. It is used in the treatment of alopecia areata, dermatitis, and bowel disease. PF-04965842 is a selective inhibitor of JAK3 and blocks signaling through this pathway. PF-04965842 has been shown to have long-term efficacy in the treatment of inflammatory skin diseases such as atopic dermatitis and psoriasis. In addition, it has been demonstrated to be effective in reducing symptoms associated with inflammatory bowel disease (IBD) and ulcerative colitis. PF-04965842 also inhibits the production of proinflammatory cytokines by inhibiting the activation of inflammatory cells in the skin or gut.
Formula:C14H21N5O2SPurity:Min. 95%Color and Shape:PowderMolecular weight:323.41 g/mol
