CAS 1627729-62-7

Formula: C23H20N4O3S

InChI: InChI=1S/C23H20N4O3S/c1-28-17-8-7-15(12-19(17)30-3)25-21-9-10-22-24-13-16(27(22)26-21)20-11-14-5-4-6-18(29-2)23(14)31-20/h4-13H,1-3H3,(H,25,26)

InChI key: NTIXYCZKSHEEOH-UHFFFAOYSA-N

SMILES: COC1=C(C=C(C=C1)NC2=NN3C(=NC=C3C4=CC5=C(S4)C(=CC=C5)OC)C=C2)OC

N-(3,4-Dimethoxyphenyl)-3-(7-methoxybenzo[b]thiophen-2-yl)imidazo[1,2-b]pyridazin-6-amine

CAS: 1627729-62-7

N-(3,4-Dimethoxyphenyl)-3-(7-methoxybenzo[b]thiophen-2-yl)imidazo[1,2-b]pyridazin-6-amine

Formula: C₂₃H₂₀N₄O₃S

Purity: 97%

Molecular weight: 432.51

Ref: 54-OR1068607

MLK-IN-1

CAS: 1627729-62-7

MLK-IN-1 is a potent and selective mixed-lineage kinase 3 (MLK-3) inhibitor, showing excellent brain penetration and high specificity for MLK-3. MLK-IN-1 at 100 nM supports sustained axonogenesis in cultures challenged with HIV-1 Tat-activated microglia and protects neuronal cells from Tat-induced damage, establishing it as a valuable probe for neuroinflammation and neurodegeneration research.

Formula: C₂₃H₂₀N₄O₃S

Purity: 99.74%

Color and Shape: Yellow Solid

Molecular weight: 432.495

Ref: TM-T39102

MLK-IN-1

CAS: 1627729-62-7

Formula: C₂₃H₂₀N₄O₃S

Purity: 99.06%

Molecular weight: 432.4949

Ref: IN-DA023IGB

MLK-IN-1

CAS: 1627729-62-7

N-(3,4-Dimethoxyphenyl)-3-(7-methoxybenzo[b]thiophen-2-yl)imidazo[1,2-b]pyridazin-6-amine

Formula: C₂₃H₂₀N₄O₃S

Purity: 97%

Molecular weight: 432.49

Ref: IN-DG01222611