CAS 1632032-53-1

3-[(4-Methylpiperazin-1-yl)carbonyl]-7-oxabicyclo[2.2.1]heptane-2-carboxylic acid

Description:

3-[(4-Methylpiperazin-1-yl)carbonyl]-7-oxabicyclo[2.2.1]heptane-2-carboxylic acid is a chemical compound characterized by its bicyclic structure, which includes a seven-membered ring fused with a six-membered ring. The presence of a carboxylic acid functional group indicates that it can participate in acid-base reactions and may exhibit solubility in polar solvents. The 4-methylpiperazine moiety contributes to its potential biological activity, as piperazine derivatives are often associated with pharmacological properties. The oxabicyclo structure suggests that the compound may have unique conformational characteristics, influencing its reactivity and interaction with biological targets. Additionally, the compound's molecular weight, polarity, and specific stereochemistry can affect its behavior in various chemical environments. Overall, this compound may be of interest in medicinal chemistry and drug development due to its structural features and potential biological applications.

Formula: C₁₃H₂₀N₂O₄

InChI: InChI=1/C13H20N2O4/c1-14-4-6-15(7-5-14)12(16)10-8-2-3-9(19-8)11(10)13(17)18/h8-11H,2-7H2,1H3,(H,17,18)/t8-,9+,10?,11?/s2

InChI key: InChIKey=JUQMLSGOTNKJKI-DEWJIBMWNA-N

SMILES: C(=O)(C1[C@]2(O[C@@](C1C(O)=O)(CC2)[H])[H])N3CCN(C)CC3

Synonyms:

• LB 100
• 3-[(4-Methylpiperazin-1-yl)carbonyl]-7-oxabicyclo[2.2.1]heptane-2-carboxylic acid
• rel-(1R,4S)-3-[(4-Methyl-1-piperazinyl)carbonyl]-7-oxabicyclo[2.2.1]heptane-2-carboxylic acid
• 7-Oxabicyclo[2.2.1]heptane-2-carboxylic acid, 3-[(4-methyl-1-piperazinyl)carbonyl]-, (1R,4S)-rel-

7-Oxabicyclo[2.2.1]heptane-2-carboxylic acid, 3-[(4-methyl-1-piperazinyl)carbonyl]-, (1R,4S)-rel-

CAS: 1632032-53-1

Formula: C₁₃H₂₀N₂O₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 268.3089

Ref: IN-DA001TUJ

LB100

CAS: 1632032-53-1

LB100

Purity: ≥98%

Molecular weight: 268.31g/mol

Ref: 54-BUP09528

LB100

CAS: 1632032-53-1

LB100 (LB-100) is a water soluble protein phosphatase 2A (PP2A) inhibitor.

Formula: C₁₃H₂₀N₂O₄

Purity: 98.63%

Color and Shape: Solid

Molecular weight: 268.31

Ref: TM-T4449

LB-100

Controlled Product

CAS: 1632032-53-1

Applications LB-100 is a small molecule inhibitor of protein phosphatase 2A with potent chemo- and radio-sensitizing potential in variety of cancer types including pancreatic cancer and colorectal cancer of human and animal model.
References Hong, C. S., et al.: Cancer Biol. Ther., 16, 821 (2015)

Formula: C₁₃H₂₀N₂O₄

Color and Shape: Neat

Molecular weight: 268.31

Ref: TR-L009025

LB-100

CAS: 1632032-53-1

LB-100 is a cell-specific drug that has been shown to inhibit the growth of cancer cells in vitro. This drug has also been shown to have an antitumor response against bowel disease and inflammatory bowel disease, as well as an anti-inflammatory effect. LB-100 is a dinucleotide phosphate that has been activated by radiation, which increases its potency. The activation of LB-100 may be due to its ability to bind to nucleic acids and inhibit the synthesis of DNA or RNA. It has also been shown to have a pharmacological effect on meningioma and cervical cancer cells in vitro.
LB-100 is a low potency drug that inhibits the synthesis of DNA or RNA by binding to nucleic acids, but does not induce apoptosis or necrosis.

Formula: C₁₃H₂₀N₂O₄

Purity: Min. 95%

Molecular weight: 268.31 g/mol

Ref: 3D-HQC03253