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CAS 163706-06-7

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Cangrelor

Description:
Cangrelor is a reversible P2Y12 platelet inhibitor used primarily in the management of acute coronary syndromes and during percutaneous coronary interventions. It is characterized by its rapid onset and offset of action, making it particularly useful in situations where immediate antiplatelet effects are required. As a nucleotide analog, Cangrelor binds to the P2Y12 receptor on platelets, preventing ADP-mediated activation and aggregation. Its pharmacokinetics are notable for a short half-life, which allows for quick recovery of platelet function after discontinuation. Cangrelor is administered intravenously, which facilitates precise control over dosing and rapid adjustments based on clinical needs. The substance is generally well-tolerated, though potential side effects may include bleeding complications, which are common with antiplatelet therapies. Overall, Cangrelor represents a significant advancement in antiplatelet therapy, particularly in acute care settings where timing and efficacy are critical.
Formula:C17H25Cl2F3N5O12P3S2
InChI:InChI=1S/C17H25Cl2F3N5O12P3S2/c1-43-5-3-23-12-9-13(26-15(25-12)44-4-2-16(20,21)22)27(7-24-9)14-11(29)10(28)8(38-14)6-37-42(35,36)39-41(33,34)17(18,19)40(30,31)32/h7-8,10-11,14,28-29H,2-6H2,1H3,(H,33,34)(H,35,36)(H,23,25,26)(H2,30,31,32)/t8-,10-,11-,14-/m1/s1
InChI key:InChIKey=PAEBIVWUMLRPSK-IDTAVKCVSA-N
SMILES:N(CCSC)C1=C2C(N(C=N2)[C@@H]3O[C@H](COP(OP(C(P(=O)(O)O)(Cl)Cl)(=O)O)(=O)O)[C@@H](O)[C@H]3O)=NC(SCCC(F)(F)F)=N1
Synonyms:
  • 5′-Adenylic acid, N-[2-(methylthio)ethyl]-2-[(3,3,3-trifluoropropyl)thio]-, anhydride with P,P′-(dichloromethylene)bis[phosphonic acid] (1:1)
  • 5′-Adenylic acid, N-[2-(methylthio)ethyl]-2-[(3,3,3-trifluoropropyl)thio]-, monoanhydride with (dichloromethylene)bis[phosphonic acid]
  • Ar-C 69931
  • Cangerlor
  • Cangrelor
  • Kengreal
  • Kengrexal
  • Zinc 85537017
  • adenosine, 5'-O-[[[(dichlorophosphonomethyl)hydroxyphosphinyl]oxy]hydroxyphosphinyl]-N-[2-(methylthio)ethyl]-2-[(3,3,3-trifluoropropyl)thio]-
  • 5'-O-[({[dichloro(phosphono)methyl](hydroxy)phosphoryl}oxy)(hydroxy)phosphoryl]-N-[2-(methylsulfanyl)ethyl]-2-[(3,3,3-trifluoropropyl)sulfanyl]adenosine
  • See more synonyms
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Found 3 products.
  • Cangrelor free acid
    Targetmol
    + Info

    Cangrelor free acid

    CAS:
    Cangrelor, a reversible P2Y12 inhibitor for IV use, was approved in June 2015; it rapidly blocks ADP-induced platelet aggregation.
    Formula:C17H25Cl2F3N5O12P3S2
    Color and Shape:Solid
    Molecular weight:776.36

    Ref: TM-T70335

  • Cangrelor
    Biosynth
    + Info

    Cangrelor

    CAS:
    <p>Cangrelor is a drug that belongs to the class of platelet aggregation inhibitors. It binds to the P2Y receptor and prevents ADP from binding, which prevents platelet activation. Cangrelor has been shown to be effective in preventing thrombotic events in patients who have undergone percutaneous coronary intervention (PCI). This drug has been shown to reduce the incidence of adverse cardiovascular events, including stent thrombosis and death from any cause, when used as an adjunct to clopidogrel or aspirin following PCI. Cangrelor may also be used for the prevention of arterial thromboembolic complications in patients undergoing total hip replacement or total knee replacement surgery.</p>
    Purity:Min. 95%
    Molecular weight:776.36 g/mol

    Ref: 3D-FC176233

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  • Cangrelor
    TRC
    + Info

    Cangrelor

    Controlled Product
    CAS:
    Formula:C17H25Cl2F3N5O12P3S2
    Color and Shape:Neat
    Molecular weight:776.359

    Ref: TR-C175230

    100mg
    623.00€