CAS 163759-94-2
:Cytidine,N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-5-methyl-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]
Description:
Cytidine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-5-methyl-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite] is a complex chemical compound primarily used in the field of nucleic acid chemistry, particularly in the synthesis of oligonucleotides. This compound features a cytidine base, which is a nucleoside composed of a pyrimidine ring and a ribose sugar, modified with various functional groups that enhance its reactivity and solubility. The presence of the phosphoramidite group allows for the incorporation of this compound into growing oligonucleotide chains during solid-phase synthesis. Additionally, the benzoyl and methoxyphenyl substituents contribute to the compound's stability and solubility in organic solvents. Its structure indicates potential applications in molecular biology, particularly in the development of therapeutic oligonucleotides and in research involving gene expression and regulation. As with many synthetic nucleosides, careful handling and storage are essential due to their sensitivity to moisture and light.
Formula:C50H60N5O10P
Synonyms:- 5-Me-DMT-2'-O-MOE-C(Bz)-CE Phosphoramidite
- 2'-O-Methyl-N4-Benzoyl-5'-O-DMT-Cytidine-3'-CE-Phosphoramidite
- N4-Benzoyl-5-methyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methyl-cytidine-3'-cyanoethyl Phosphoramidite
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Found 8 products.
N4-Benzoyl-5'-O-DMT-2'-O-methylcytidine 3'-CE phosphoramidite
CAS:Formula:C50H60N5O10PPurity:97%Color and Shape:SolidMolecular weight:922.01272'-O-MOE-5-Me-C(Bz)
CAS:<p>Nucleoside Phosphoramidites; Ready for phosphorylation</p>Formula:C50H60N5O10PColor and Shape:SolidMolecular weight:922.01DMT-2'-O-MOE-5-Me-rC(Bz) Phosphoramidite
CAS:Formula:C50H60N5O10PPurity:>95.0%(HPLC)(qNMR)Color and Shape:White to Yellow powder to crystalMolecular weight:922.03N4-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)-5-methylcytidine 3'-CE phosphoramidite
CAS:<p>Nucleoside phosphoramidites are used in the chemical synthesis of oligonucleotides. Using a chemical approach rather than an enzymatic one allows quick and inexpensive access to custom-made oligonucleotides of the desired sequence. Differently from the enzymatic synthesis, the chemically synthesised oligonucleotide sequence is typically constructed in a 3’ to 5’ direction. N4-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)-5-methylcytidine 3'-CE phosphoramidite, also called 5-Me-DMT-2'-O-MOE-C(Bz)-CEP, has been used in the synthesis of oligonucleotides which are specifically hybridizable with nucleic acids encoding multidrug resistant-associated protein (MRP). The antisense oligonucleotide ISIS 13041 gave almost complete removal of resistance to vincristine, a chemotherapy drug.</p>Formula:C50H60N5O10PPurity:Min. 95%Color and Shape:White PowderMolecular weight:922.01 g/molN4-Benzoyl-5'-O-DMT-2'-O-methylcytidine 3'-CE phosphoramidite
CAS:Controlled ProductFormula:C50H60N5O10PColor and Shape:NeatMolecular weight:863.933







