CAS 16391-75-6

29-Nordammara-17(20),24-dien-21-oic acid, 16-(acetyloxy)-3,11-dihydroxy-, (3α,4α,8α,9β,11α,13α,14β,16β,17Z)-, compd. with 2,2′-iminobis[ethanol] (1:1)

Description:

29-Nordammara-17(20),24-dien-21-oic acid, 16-(acetyloxy)-3,11-dihydroxy-, is a complex organic compound characterized by its unique steroidal structure, which includes multiple hydroxyl groups and an acetyloxy functional group. This compound features a specific stereochemistry, denoted by its detailed configuration, which influences its biological activity and interactions. The presence of the 2,2′-iminobis[ethanol] indicates that it forms a 1:1 complex with this amine, potentially affecting its solubility and reactivity. The compound is likely to exhibit various pharmacological properties, given its structural features, which may include anti-inflammatory or other therapeutic effects. Its CAS number, 16391-75-6, allows for precise identification in chemical databases. Overall, the characteristics of this substance suggest it may have applications in medicinal chemistry or pharmacology, although specific biological activities would require further investigation through empirical studies.

Formula: C₃₁H₄₈O₆·C₄H₁₁NO₂

InChI: InChI=1S/C31H48O6.C4H11NO2/c1-17(2)9-8-10-20(28(35)36)26-22-15-24(34)27-29(5)13-12-23(33)18(3)21(29)11-14-30(27,6)31(22,7)16-25(26)37-19(4)32;6-3-1-5-2-4-7/h9,18,21-25,27,33-34H,8,10-16H2,1-7H3,(H,35,36);5-7H,1-4H2/b26-20-;/t18-,21-,22-,23+,24+,25-,27-,29-,30-,31-;/m0./s1

InChI key: InChIKey=OQZZCXRLEFBPLZ-JCJNLNMISA-N

SMILES: C[C@@]12[C@]3(C)[C@](/C(=C(\CCC=C(C)C)/C(O)=O)/[C@@H](OC(C)=O)C3)(C[C@@H](O)[C@]1([C@]4(C)[C@@](CC2)([C@H](C)[C@H](O)CC4)[H])[H])[H].N(CCO)CCO

Synonyms:

• (2Z)-2-[(3alpha,4alpha,5alpha,8alpha,9xi,11alpha,13alpha,14beta,16beta,17Z)-16-(acetyloxy)-3,11-dihydroxy-4,8,10,14-tetramethylgonan-17-ylidene]-6-methylhept-5-enoic acid - 2,2'-iminodiethanol (1:1)
• (3alpha,8alpha,9beta,13alpha,14beta,16beta,17(Z))-16-(Acetyloxy)-3,11-dihydroxy-29-nordammara-17(20),24-dien-21-oic acid, compd. with 2,2'-iminobis(ethanol) (1:1)
• (4alpha,8alpha,9beta,13alpha,14beta,17Z)-16beta-Acetoxy-3alpha,11alpha-dihydroxy-29-nordammara-17(20),24-dien-21-oic acid, compound with 2,2'-iminodiethanol (1:1)
• 29-Nor-8α,9β,13α,14β-dammara-17(20),24-dien-21-oic acid, 3α,11α,16β-trihydroxy-, 16-acetate, compd. with 2,2′-iminodiethanol (1:1), (Z)-
• 29-Nordammara-17(20),24-dien-21-oic acid, 16-(acetyloxy)-3,11-dihydroxy-, (3α,4α,8α,9β,11α,13α,14β,16β,17Z)-, compd. with 2,2′-iminobis[ethanol] (1:1)
• Diethanolamine fusidate
• Ethanol, 2,2′-iminobis-, (3α,4α,8α,9β,11α,13α,14β,16β,17Z)-16-(acetyloxy)-3,11-dihydroxy-29-nordammara-17(20),24-dien-21-oate (salt)

Diethanolamine fusidate

CAS: 16391-75-6

Diethanolamine fusidate

Formula: C₃₁H₄₇NaO₆ / C₃₁H₄₈O₆

Purity: 81.2% / 77.8%

Color and Shape: White

Molecular weight: 538.32703 / 516.34509

Ref: 47-118

Diethanolamine Fusidate

CAS: 16391-75-6

Formula: C₃₅H₅₉NO₈

Color and Shape: Solid

Molecular weight: 621.8449

Ref: IN-DA001UJN

Diethanolamine Fusidate

CAS: 16391-75-6

Formula: C₃₁H₄₈O₆·C₄H₁₁NO₂

Color and Shape: White To Off-White Solid

Molecular weight: 516.72 105.14

Ref: 4Z-F-5418

Diethanolamine Fusidate

CAS: 16391-75-6

Color and Shape: Neat

Ref: 86-MM3832.00

Diethanolamine Fusidate

CAS: 16391-75-6

Stability Hygroscopic
Applications A bacteriostatic antibiotic with similar activity and better absorption after oral administration (in animals) than the sodium salt of Fusidic Acid (F865500). Inhibits protein synthesis in prokaryotes by inhibiting the ribosome-dependent activity of G factor and translocation of peptidyl-tRNA.
References Findon, G. et al.: Lab. Anim. Sci., 41, 462 (1991); Parsons, R.L. et al.: Curr. Chemother. Proc. Int. Cong. Chemother., 10, 384 (1978);

Formula: C₃₁H₄₈O₆·C₄H₁₁NO₂

Color and Shape: Neat

Molecular weight: 621.84

Ref: TR-D441880

Diethanolamine Fusidate

CAS: 16391-75-6

Diethanolamine Fusidate: orally better-absorbed bacteriostatic antibiotic; inhibits protein synthesis in prokaryotes.

Formula: C₃₅H₅₉NO₈

Color and Shape: Solid

Molecular weight: 621.86

Ref: TM-T70323

Diethanolamine fusidate

CAS: 16391-75-6

Diethanolamine fusidate is an aminoglycoside antibiotic that inhibits protein synthesis in bacteria by binding to the ribosomes. It binds to bacterial 16S ribosomal RNA and inhibits protein synthesis, leading to cell death by inhibiting the production of proteins vital for cell division. Diethanolamine fusidate has been shown to be effective against methicillin-resistant Staphylococcus aureus (MRSA) and Pseudomonas aeruginosa, although is not active against acid-fast bacteria such as Mycobacterium tuberculosis or Mycobacterium avium complex. This drug also has anti-inflammatory properties, which may be due to its inhibition of prostaglandin synthesis.

Formula: C₃₅H₅₉NO₈

Purity: 95%Min

Molecular weight: 621.84 g/mol

Ref: 3D-FD173301