CAS 1639220-15-7

Sigma-1 receptor antagonist 2

CAS: 1639220-15-7

Formula: C₂₀H₂₆ClN₃O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 375.8923

Ref: IN-DA01V3OU

Sigma-1 receptor antagonist 2

CAS: 1639220-15-7

Sigma-1 receptor antagonist 2

Formula: C₂₀H₂₆ClN₃O₂

Purity: ≥98%

Molecular weight: 375.89

Ref: 54-BUP12627

5-​Chloro-​2-​(4-​methoxyphenyl)​-​4-​methyl-​6-​[3-​(1-​piperidinyl)​propoxy]​-pyrimidine

CAS: 1639220-15-7

5-Chloro-2- (4-methoxyphenyl) -4-methyl-6-[3-(1-piperidinyl) propoxy] pyrimidine is a research tool that can be used in the study of ion channels and protein interactions. It has been shown to inhibit the activity of human recombinant beta 2 adrenergic receptor at low micromolar concentrations, with an IC50 of 5.1±0.5 μM. The binding affinity for this ligand is stronger than that of propranolol (IC50=8.5±0.7 μM).

Formula: C₂₀H₂₆ClN₃O₂

Purity: Min. 95%

Molecular weight: 375.9 g/mol

Ref: 3D-PQC22015

Sigma-1 receptor antagonist 2

CAS: 1639220-15-7

Sigma-1 receptor antagonist 2 is a more potent and selective antagonist of sigma 1 receptor (σ1 R, Ki = 3.88 nM) than σ2 receptor (Ki = 1288 nM).

Formula: C₂₀H₂₆ClN₃O₂

Purity: 99.6%

Color and Shape: Solid

Molecular weight: 375.89

Ref: TM-T12911