CAS 16409-34-0

Sodium glycodeoxycholate

Description:

Sodium glycodeoxycholate is a bile salt derived from deoxycholic acid, which is a secondary bile acid formed from the bacterial metabolism of primary bile acids in the intestine. It is characterized by its amphipathic nature, possessing both hydrophilic and hydrophobic properties, which allows it to function effectively as a surfactant and emulsifying agent. This compound plays a crucial role in the digestion and absorption of dietary fats and fat-soluble vitamins in the gastrointestinal tract. Sodium glycodeoxycholate is typically used in various biochemical and pharmaceutical applications, including drug formulation and as a solubilizing agent. Its structure includes a glycine moiety, which enhances its solubility in aqueous environments. Additionally, it has been studied for its potential effects on cell membranes and its role in various physiological processes. Safety and handling precautions should be observed, as with any chemical substance, due to its biological activity and potential effects on human health.

Formula: C₂₆H₄₃NO₅·Na

InChI: InChI=1S/C26H43NO5.Na/c1-15(4-9-23(30)27-14-24(31)32)19-7-8-20-18-6-5-16-12-17(28)10-11-25(16,2)21(18)13-22(29)26(19,20)3;/h15-22,28-29H,4-14H2,1-3H3,(H,27,30)(H,31,32);/t15-,16-,17-,18+,19-,20+,21+,22+,25+,26-;/m1./s1

InChI key: InChIKey=IIYSTUUVIASHBG-YEUHZSMFSA-N

SMILES: C[C@@]12[C@]([C@]3([C@@]([C@]4(C)[C@](CC3)(C[C@H](O)CC4)[H])(C[C@@H]1O)[H])[H])(CC[C@@]2([C@@H](CCC(NCC(O)=O)=O)C)[H])[H].[Na]

Synonyms:

• Cholane, glycine deriv.
• Glycine, N-(3α,12α-dihydroxy-5β-cholan-24-oyl)-, monosodium salt
• Glycine, N-[(3α,5β,12α)-3,12-dihydroxy-24-oxocholan-24-yl]-, monosodium salt
• Glycine, N-[(3α,5β,12α)-3,12-dihydroxy-24-oxocholan-24-yl]-, sodium salt (1:1)
• Glycodeoxycholic acid sodium salt
• Sodium deoxyglycolate
• Sodium glycodeoxycholate
• Sodium glycyldeoxycholate
• glycine, N-[(3alpha,5beta,12alpha)-3,12-dihydroxy-24-oxocholan-24-yl]-, monosodium salt

GLYCINE, N-[(3Α,5Β,12Α)-3,12-DIHYDROXY-24-OXOCHOLAN-24-YL]-, SODIUM SALT (1:1)

CAS: 16409-34-0

Formula: C₂₆H₄₂NNaO₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 471.6051

Ref: IN-DA001UN4

Glycodeoxycholate Sodium

CAS: 16409-34-0

Glycodeoxycholate Sodium

Formula: C₂₆H₄₂NNaO₅

Purity: ≥95%

Molecular weight: 471.61

Ref: 54-BUP16581

Sodium glycodeoxycholate

CAS: 16409-34-0

Formula: C₂₆H₄₂NNaO₅

Purity: ≥ 97.0%

Color and Shape: White to off-white powder

Molecular weight: 471.61

Ref: 7W-GK3611

Sodium Glycodeoxycholate

CAS: 16409-34-0

Formula: C26H43NO5.Na

Purity: >98%

Color and Shape: Solid

Molecular weight: 472.61

Ref: 48-65-1010

Glycodeoxycholate Sodium (Standard)

CAS: 16409-34-0

Glycodeoxycholate Sodium (Standard) is a reference standard for research and analysis in studies involving Glycodeoxycholate Sodium. The mechanism by which Glycodeoxycholate Sodium induces apoptosis in hepatocytes is related to DNA cleavage by endonucleases. It is a secondary bile acid produced by the action of enzymes present in the microflora of the colonic environment.

Formula: C₂₆H₄₂NNaO₅

Color and Shape: Solid

Molecular weight: 471.61

Ref: TM-TMSM-3195

Glycodeoxycholate Sodium

CAS: 16409-34-0

Glycodeoxycholate Sodium, a secondary bile acid, triggers hepatocyte apoptosis via DNA endonuclease cleavage.

Formula: C₂₆H₄₂NNaO₅

Purity: 97.21% - 99.57%

Color and Shape: Solid

Molecular weight: 471.61

Ref: TM-T5254

Glycodeoxycholic Acid Sodium Salt

Controlled Product

CAS: 16409-34-0

Stability Hygroscopic
Applications Glycodeoxycholic acid is a bile acid that induces severe pancreatitis in rats.
References Houghton, A., et al.: Neuroreport, 8, 3795 (1997); Lake, A., et al.: Toxicol. Appl. Pharm., 268, 132 (2013); Zhao, X., et al.: Scand. J. Gastroentero., 37, 1351 (2002)

Formula: C₂₆H₄₂NO₅·Na

Color and Shape: Neat

Molecular weight: 471.61

Ref: TR-G641400

Glycodeoxycholic acid sodium salt

Controlled Product

CAS: 16409-34-0

Glycodeoxycholic acid sodium salt is a bile acid derivative, which is a biochemical compound sourced from the metabolism of bile acids in the liver. It plays a role in bile acid signaling pathways and lipid emulsification. The mode of action involves mimicking natural bile acids, facilitating the emulsification and absorption of dietary fats in the gastrointestinal tract, and potentially participating in signaling pathways that regulate cholesterol metabolism.

Formula: C₂₆H₄₂NNaO₅

Purity: Min. 95 Area-%

Color and Shape: White Powder

Molecular weight: 471.61 g/mol

Ref: 3D-FG16281