CAS 1644461-81-3

Ticagrelor Related Compound 15

CAS: 1644461-81-3

Formula: C₂₀H₂₂F₂N₆O₅

Color and Shape: White To Off-White Solid

Molecular weight: 464.43

Ref: 4Z-T-8126

5-Desthiopropyl-5-hydroxy-ticagrelor

Controlled Product

CAS: 1644461-81-3

Applications 5-Desthiopropyl-5-hydroxy-ticagrelor is a related compound of ticagrelor (T437700). Ticagrelor, the first reversible oral P2Y12 receptor antagonist, provides faster, greater, and more consistent ADP-receptor inhibition than Clopidogrel. Used in the treatment of acute coronary syndromes (ACS).
References Matetzky, S., et al.: Circulation, 109, 3171 (2004), Bassand, J., et al.: Eur. Heart J., 28, 1598 (2007), Jakubowski, J., et al.: Cardiovasc. Drug Rev., 25, 357 (2007),

Formula: C₂₀H₂₂F₂N₆O₅

Color and Shape: Neat

Molecular weight: 464.42

Ref: TR-D297505

5-Desthiopropyl-5-hydroxy-ticagrelor

CAS: 1644461-81-3

5-Desthiopropyl-5-hydroxy-ticagrelor is a synthetic and new chemical entity, which is a prodrug. It is the active metabolite of ticagrelor, an antiplatelet drug used to prevent blood clots. Ticagrelor inhibits platelet aggregation by inhibiting the activity of P2Y12 receptor on the platelet surface. 5-Desthiopropyl-5-hydroxy-ticagrelor has an analytical purity of >97% and a pharmacopoeia grade purity of >99%. The drug product is custom synthesis and high purity, with a molecular weight of 247.9 Da. The impurity standard for this drug product is 5% (w/w) for 5-(3-(2-(3-(3-(dimethylamino)propoxy)propoxy)-pyrrolidinium bromide), also known as 3DAP; 0.1% (w

Formula: C₂₀H₂₂F₂N₆O₅

Purity: Min. 95%

Molecular weight: 464.40 g/mol

Ref: 3D-UQC46181