CAS 1645308-94-6
:FMOC-MeThr(Me)-OH
Description:
FMOC-MeThr(Me)-OH, also known as 9-fluorenylmethoxycarbonyl-2-amino-3-methylbutanoic acid, is a chemical compound commonly used in peptide synthesis as a protecting group for amino acids. The FMOC (9-fluorenylmethoxycarbonyl) group is a popular choice due to its stability under basic conditions and ease of removal under mild acidic conditions, making it advantageous for sequential peptide synthesis. The presence of the methyl groups in the structure contributes to its steric hindrance, which can influence the reactivity and conformation of the molecule. This compound is typically utilized in solid-phase peptide synthesis, where it helps to protect the amino group during the coupling reactions. Its solubility in organic solvents and stability under various reaction conditions make it a valuable reagent in organic and medicinal chemistry. Additionally, the specific arrangement of functional groups in FMOC-MeThr(Me)-OH allows for selective reactions, facilitating the synthesis of complex peptides with desired biological activities.
Formula:C21H23NO5
Synonyms:- FMOC-MeThr(Me)-OH
- (2S,3R)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}(methyl)amino)-3-methoxybutanoic acid
- L-Threonine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-N,O-dimethyl-
- N-Fmoc-N,O-dimethyl-L-threonine
- Fmoc-N-Me-Thr(Me)-OH
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