CAS 16564-43-5

Sodium glycochenodeoxycholate

Description:

Sodium glycochenodeoxycholate is a bile salt derived from the conjugation of glycine and chenodeoxycholic acid, which is a primary bile acid. It is characterized by its amphipathic nature, possessing both hydrophilic and hydrophobic properties, which allows it to effectively emulsify fats and facilitate their digestion and absorption in the intestine. This compound is typically found in the bile and plays a crucial role in lipid metabolism. As a sodium salt, it is soluble in water, making it useful in various biochemical applications, including as a surfactant and in cell lysis protocols. The substance is also known for its potential use in drug delivery systems and as a component in formulations for pharmaceutical and cosmetic products. Its molecular structure includes a steroid nucleus, a carboxyl group, and a glycine moiety, contributing to its biological activity. Safety data indicates that while it is generally regarded as safe in appropriate concentrations, caution should be exercised due to its potential irritant properties.

Formula: C₂₆H₄₃NO₅·Na

InChI: InChI=1S/C26H43NO5.Na/c1-15(4-7-22(30)27-14-23(31)32)18-5-6-19-24-20(9-11-26(18,19)3)25(2)10-8-17(28)12-16(25)13-21(24)29;/h15-21,24,28-29H,4-14H2,1-3H3,(H,27,30)(H,31,32);/t15-,16+,17-,18-,19+,20+,21-,24+,25+,26-;/m1./s1

InChI key: InChIKey=JIHVOAVQLCYLKZ-YRJJIGPTSA-N

SMILES: C[C@@]12[C@]([C@]3([C@@]([C@]4(C)[C@](C[C@H]3O)(C[C@H](O)CC4)[H])(CC1)[H])[H])(CC[C@@]2([C@@H](CCC(NCC(O)=O)=O)C)[H])[H].[Na]

Synonyms:

• Dshs 00533
• Glycine, N-(3α,7α-dihydroxy-5β-cholan-24-oyl)-, monosodium salt
• Glycine, N-[(3α,5β,7α)-3,7-dihydroxy-24-oxocholan-24-yl]-, monosodium salt
• Glycine, N-[(3α,5β,7α)-3,7-dihydroxy-24-oxocholan-24-yl]-, sodium salt (1:1)
• Glycochenodeoxycholic Acid Sodium
• NSC 681056
• Sodium [(3,7-Dihydroxy-24-Oxocholan-24-Yl)Amino]Acetate
• Sodium chenodeoxycholylglycine
• Sodium glycochenodeoxycholate
• Sodium glycochenodesoxycholate
• Sodium glycylchenodeoxycholate
• glycine, N-[(3alpha,5beta,7alpha)-3,7-dihydroxy-24-oxocholan-24-yl]-, monosodium salt

Glycine, N-[(3α,5β,7α)-3,7-dihydroxy-24-oxocholan-24-yl]-, sodium salt (1:1)

CAS: 16564-43-5

Formula: C₂₆H₄₂NNaO₅

Purity: 97%

Color and Shape: Solid

Molecular weight: 471.6051

Ref: IN-DA001WA1

Glycochenodeoxycholic Acid Sodium Salt (Sodium Glycochenodeoxycholate)

CAS: 16564-43-5

Formula: C₂₆H₄₂NO₅·Na

Color and Shape: White To Off-White Solid

Molecular weight: 448.63 22.99

Ref: 4Z-C-5721

Glycochenodeoxycholic acid sodium salt

CAS: 16564-43-5

Glycochenodeoxycholic acid sodium salt

Formula: C₂₆H₄₂NO₅·Na

Purity: 95%

Color and Shape: white solid

Molecular weight: 471.60514g/mol

Ref: 54-OR933168

Glycochenodeoxycholic acid sodium salt

CAS: 16564-43-5

Glycochenodeoxycholic acid sodium salt

Purity: ≥95%

Molecular weight: 471.61g/mol

Ref: 54-BUP16579

Glycochenodeoxycholic acid sodium salt

CAS: 16564-43-5

Formula: C₂₆H₄₂NNaO₅

Purity: (dried basis) ≥ 97.0%

Color and Shape: White to off-white powder

Molecular weight: 471.61

Ref: 7W-GK7114

Glycochenodeoxycholic acid sodium salt

CAS: 16564-43-5

GCDCA, a bile acid-glycine salt, is a secondary bile acid from colonic microbes.

Formula: C₂₆H₄₂NNaO₅

Purity: 95.48% - 99.82%

Color and Shape: Solid

Molecular weight: 471.61

Ref: TM-T5259

Glycochenodeoxycholic Acid Sodium, 95%

Controlled Product

CAS: 16564-43-5

Stability Hygroscopic
Applications Glycochenodeoxycholic Acid Sodium Salt is a bile salt formed in the liver from chenodeoxycholate and glycine. It acts as a detergent to solubilize fats for absorption and is itself absorbed. It is a cholagogue and choleretic.
References Ollila, F., et al.: Langmuir, 17, 7107 (2001), Uekama, K., et al.: Chem. Pharm. Bull., 52, 900 (2004), Tongiani, S., et al.: J. Pharm. Sci., 94, 2380 (2005),

Formula: C₂₆H₄₂NO₅·Na

Purity: 95%

Color and Shape: White To Light Brown

Molecular weight: 471.61

Ref: TR-G641255

Glycochenodeoxycholic Acid-d7 Sodium Salt (Major)

Controlled Product

CAS: 16564-43-5

Stability Very Hygroscopic
Applications Labelled Glycochenodeoxycholic Acid (G641255). A bile salt formed in the liver from chenodeoxycholate and glycine, usually as the sodium salt. It acts as a detergent to solubilize fats for absorption and is itself absorbed. It is a cholagogue and choleretic.
References Ollila, F., et al.: Langmuir, 17, 7107 (2001), Uekama, K., et al.: Chem. Pharm. Bull., 52, 900 (2004), Tongiani, S., et al.: J. Pharm. Sci., 94, 2380 (2005),

Formula: C₂₆H₃₅D₇NNaO₅

Color and Shape: Off-White

Molecular weight: 478.65

Ref: TR-G641257

Glycochenodeoxycholic Acid Sodium Salt (Ultra pure, >97%)

Controlled Product

CAS: 16564-43-5

Applications Glycochenodeoxycholic Acid Sodium Salt is a bile salt formed in the liver from chenodeoxycholate and glycine. It acts as a detergent to solubilize fats for absorption and is itself absorbed. It is a cholagogue and choleretic.
References Ollila, F., et al.: Langmuir, 17, 7107 (2001); Uekama, K., et al.: Chem. Pharm. Bull., 52, 900 (2004); Tongiani, S., et al.: J. Pharm. Sci., 94, 2380 (2005)

Formula: C₂₆H₄₂NO₅·Na

Purity: >97%

Color and Shape: White To Light Brown

Molecular weight: 471.61

Ref: TR-G641260

Glycochenodeoxycholic acid, sodium salt

CAS: 16564-43-5

Glycochenodeoxycholic acid is a bile salt used in bacteriological culture media as selective inhibitory agent. Enteric bacteria are resistant to the bactericidal effects of bile salts.

Formula: C₂₆H₄₂NNaO₅

Purity: Min. 90.0 Area-%

Molecular weight: 471.61 g/mol

Ref: 3D-G-5222

Glycochenodeoxycholic acid sodium salt

CAS: 16564-43-5

Glycochenodeoxycholic acid sodium salt is a bile acid derivative, which is an important component of the bile produced in the liver. It originates from the metabolism and conjugation of chenodeoxycholic acid with glycine, a process that occurs in the liver. This compound plays a significant role in the emulsification and solubilization of dietary fats, which facilitates their absorption in the intestines.

Formula: C₂₆H₄₂NNaO₅

Purity: Min. 96 Area-%

Color and Shape: White Off-White Powder

Molecular weight: 471.61 g/mol

Ref: 3D-FG15494

Sodium Glycochenodeoxycholate

CAS: 16564-43-5

Formula: C₂₆H₄₂NNaO₅

Purity: >95.0%(T)(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 471.61

Ref: 3B-O0530

Sodium Glycochenodeoxycholate (SGCDC) extrapure, 97%

CAS: 16564-43-5

Formula: C₂₆H₄₂NNaO₅

Purity: min. 97%

Color and Shape: White to off-white, Crystalline powder

Molecular weight: 471.61

Ref: SR-97971

epi-Glycochenodeoxycholic Acid Sodium Salt-d7

Controlled Product

CAS: 16564-43-5

Applications epi-Glycochenodeoxycholic Acid Sodium Salt-d7 is a labelled epimer analogue of Glycochenodeoxycholic Acid Sodium Salt (G641255), which is a bile salt formed in the liver from chenodeoxycholate and glycine. It acts as a detergent to solubilize fats for absorption and is itself absorbed. It is a cholagogue and choleretic.
References Ollila, F., et al.: Langmuir, 17, 7107 (2001); Uekama, K., et al.: Chem. Pharm. Bull., 52, 900 (2004); Tongiani, S., et al.: J. Pharm. Sci., 94, 2380 (2005);

Formula: C₂₆D₇H₃₅NNaO₅

Color and Shape: Neat

Molecular weight: 478.648

Ref: TR-G641267