CAS 165800-04-4: Eperezolid

Description: Eperezolid is a synthetic antibiotic that belongs to the oxazolidinone class of compounds. It is primarily characterized by its mechanism of action, which involves the inhibition of bacterial protein synthesis by binding to the 50S ribosomal subunit. This action makes it effective against a range of Gram-positive bacteria, including strains resistant to other antibiotics. Eperezolid has been studied for its potential use in treating infections caused by multidrug-resistant pathogens. In terms of its chemical properties, it typically exhibits good oral bioavailability and a favorable pharmacokinetic profile. However, like other antibiotics, it may be associated with side effects, including gastrointestinal disturbances and potential hematological effects. The compound's development has been part of ongoing research efforts to combat antibiotic resistance, highlighting the importance of novel therapeutic agents in modern medicine. As with any pharmaceutical, its use should be guided by susceptibility patterns and clinical considerations.

Formula: C₁₈H₂₃FN₄O₅

InChI: InChI=1S/C18H23FN4O5/c1-12(25)20-9-14-10-23(18(27)28-14)13-2-3-16(15(19)8-13)21-4-6-22(7-5-21)17(26)11-24/h2-3,8,14,24H,4-7,9-11H2,1H3,(H,20,25)/t14-/m0/s1

InChI key: InChIKey=SIMWTRCFFSTNMG-AWEZNQCLSA-N

SMILES: O=C1OC(CNC(=O)C)CN1C2=CC=C(C(F)=C2)N3CCN(C(=O)CO)CC3

Synonyms:

• Acetamide, N-((3-(3-fluoro-4-(4-(hydroxyacetyl)-1-piperazinyl)phenyl)-2-oxo-5-oxazolidinyl)methyl)-, (S)-
• Acetamide, N-((3-(3-fluoro-4-(4-(hydroxyacetyl)-1-piperazynyl)phenyl)- 2-oxo-5-oxazolidinyl)methyl)-, (S)-
• Acetamide, N-[[(5S)-3-[3-fluoro-4-[4-(2-hydroxyacetyl)-1-piperazinyl]phenyl]-2-oxo-5-oxazolidinyl]methyl]-
• Acetamide, N-[[(5S)-3-[3-fluoro-4-[4-(hydroxyacetyl)-1-piperazinyl]phenyl]-2-oxo-5-oxazolidinyl]methyl]-
• Eperezolid [USAN]
• N-(((S)-3-(3-fluoro-4-(4-glycoloyl-1-piperazinyl)phenyl)-2-oxo-5-oxazolidinyl)methyl)acetamide
• N-[[(5S)-3-[3-Fluoro-4-[4-(2-hydroxyacetyl)-1-piperazinyl]phenyl]-2-oxo-5-oxazolidinyl]methyl]acetamide
• N-{[(5S)-3-{3-fluoro-4-[4-(hydroxyacetyl)piperazin-1-yl]phenyl}-2-oxo-1,3-oxazolidin-5-yl]methyl}acetamide
• Pnu 100592
• U 100592
• Unii-C460Zsu1Ow
• Eperezolid

Eperezolid

CAS: 165800-04-4

Eperezolid (PNU-100592), an oxazolidinone antibiotic, inhibits staphylococci (MIC90=1-4 mg/ml) effectively, methicillin resistance notwithstanding.

• Formula: C₁₈H₂₃FN₄O₅
• Purity: 96.18%
• Color and Shape: Solid
• Molecular weight: 394.4

eperezolid

CAS: 165800-04-4

• Formula: C₁₈H₂₃FN₄O₅
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 394.3974

Eperezolid

CAS: 165800-04-4

• Formula: C₁₈H₂₃FN₄O₅
• Molecular weight: 394.40

(S)-N-[[3-[3-Fluoro-4-[4-(Hydroxyacetyl)-1-Piperazinyl]-Phenyl]-2-Oxo-5-Oxazolidinyl]Methyl]Acetamide

CAS: 165800-04-4

• Molecular weight: 394.4g/mol

Eperezolid

CAS: 165800-04-4

• Purity: ≥95%
• Molecular weight: 394.4g/mol

Eperezolid

CAS: 165800-04-4

• Formula: C₁₈H₂₃FN₄O₅
• Color and Shape: White To Off-White Solid
• Molecular weight: 394.41

Eperezolid

CAS: 165800-04-4

• Formula: C₁₈H₂₃FN₄O₅
• Color and Shape: Neat
• Molecular weight: 394.397

Eperezolid-d8

CAS: 165800-04-4

• Formula: C₁₈H₁₅D₈FN₄O₅
• Color and Shape: Neat
• Molecular weight: 183.168

Eperezolid-d3

CAS: 165800-04-4

• Formula: C₁₈H₂₀D₃FN₄O₅
• Color and Shape: Neat
• Molecular weight: 260.284

Eperezolid

CAS: 165800-04-4

Eperezolid is an antimicrobial agent that belongs to the class of oxazolidinones. It has potent …

• Formula: C₁₈H₂₃FN₄O₅
• Purity: Min. 95%
• Molecular weight: 394.4 g/mol