CAS 165800-04-4

Eperezolid

Description:

Eperezolid is a synthetic antibiotic that belongs to the oxazolidinone class of compounds. It is primarily characterized by its mechanism of action, which involves the inhibition of bacterial protein synthesis by binding to the 50S ribosomal subunit. This action makes it effective against a range of Gram-positive bacteria, including strains resistant to other antibiotics. Eperezolid has been studied for its potential use in treating infections caused by multidrug-resistant pathogens. In terms of its chemical properties, it typically exhibits good oral bioavailability and a favorable pharmacokinetic profile. However, like other antibiotics, it may be associated with side effects, including gastrointestinal disturbances and potential hematological effects. The compound's development has been part of ongoing research efforts to combat antibiotic resistance, highlighting the importance of novel therapeutic agents in modern medicine. As with any pharmaceutical, its use should be guided by susceptibility patterns and clinical considerations.

Formula: C₁₈H₂₃FN₄O₅

InChI: InChI=1S/C18H23FN4O5/c1-12(25)20-9-14-10-23(18(27)28-14)13-2-3-16(15(19)8-13)21-4-6-22(7-5-21)17(26)11-24/h2-3,8,14,24H,4-7,9-11H2,1H3,(H,20,25)/t14-/m0/s1

InChI key: InChIKey=SIMWTRCFFSTNMG-AWEZNQCLSA-N

SMILES: O=C1N(C2=CC(F)=C(C=C2)N3CCN(C(CO)=O)CC3)C[C@H](CNC(C)=O)O1

Synonyms:

• Acetamide, N-((3-(3-fluoro-4-(4-(hydroxyacetyl)-1-piperazinyl)phenyl)-2-oxo-5-oxazolidinyl)methyl)-, (S)-
• Acetamide, N-((3-(3-fluoro-4-(4-(hydroxyacetyl)-1-piperazynyl)phenyl)- 2-oxo-5-oxazolidinyl)methyl)-, (S)-
• Acetamide, N-[[(5S)-3-[3-fluoro-4-[4-(2-hydroxyacetyl)-1-piperazinyl]phenyl]-2-oxo-5-oxazolidinyl]methyl]-
• Acetamide, N-[[(5S)-3-[3-fluoro-4-[4-(hydroxyacetyl)-1-piperazinyl]phenyl]-2-oxo-5-oxazolidinyl]methyl]-
• Eperezolid [USAN]
• N-(((S)-3-(3-fluoro-4-(4-glycoloyl-1-piperazinyl)phenyl)-2-oxo-5-oxazolidinyl)methyl)acetamide
• N-[[(5S)-3-[3-Fluoro-4-[4-(2-hydroxyacetyl)-1-piperazinyl]phenyl]-2-oxo-5-oxazolidinyl]methyl]acetamide
• N-{[(5S)-3-{3-fluoro-4-[4-(hydroxyacetyl)piperazin-1-yl]phenyl}-2-oxo-1,3-oxazolidin-5-yl]methyl}acetamide
• Pnu 100592
• U 100592
• Unii-C460Zsu1Ow

Eperezolid

CAS: 165800-04-4

Eperezolid (PNU-100592), an oxazolidinone antibiotic, inhibits staphylococci (MIC90=1-4 mg/ml) effectively, methicillin resistance notwithstanding.

Formula: C₁₈H₂₃FN₄O₅

Purity: 96.18%

Color and Shape: Solid

Molecular weight: 394.4

Ref: TM-T15237

Eperezolid

CAS: 165800-04-4

Formula: C₁₈H₂₃FN₄O₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 394.3974

Ref: IN-DA00ABJW

Eperezolid

CAS: 165800-04-4

Formula: C₁₈H₂₃FN₄O₅

Molecular weight: 394.40

Ref: 7W-GA7890

(S)-N-[[3-[3-Fluoro-4-[4-(Hydroxyacetyl)-1-Piperazinyl]-Phenyl]-2-Oxo-5-Oxazolidinyl]Methyl]Acetamide

CAS: 165800-04-4

(S)-N-[[3-[3-Fluoro-4-[4-(Hydroxyacetyl)-1-Piperazinyl]-Phenyl]-2-Oxo-5-Oxazolidinyl]Methyl]Acetamide

Formula: C₁₈H₂₃FN₄O₅

Purity: 98+%

Molecular weight: 394.4

Ref: 54-PC108590

Eperezolid

CAS: 165800-04-4

Eperezolid

Formula: C₁₈H₂₃FN₄O₅

Purity: ≥95%

Molecular weight: 394.4

Ref: 54-BUP08487

Eperezolid

CAS: 165800-04-4

Formula: C₁₈H₂₃FN₄O₅

Color and Shape: White To Off-White Solid

Molecular weight: 394.41

Ref: 4Z-E-084001

(S)-N-((3-(3-Fluoro-4-(4-(2-hydroxyacetyl)piperazin-1-yl)phenyl)-2-oxooxazolidin-5-yl)methyl)acetamide

CAS: 165800-04-4

Purity: 98%

Molecular weight: 394.4030151

Ref: 10-F436586

Eperezolid-d3

Controlled Product

CAS: 165800-04-4

Formula: C₁₈H₂₀D₃FN₄O₅

Color and Shape: Neat

Molecular weight: 260.284

Ref: TR-E565742

Eperezolid-d8

Controlled Product

CAS: 165800-04-4

Formula: C₁₈H₁₅D₈FN₄O₅

Color and Shape: Neat

Molecular weight: 183.168

Ref: TR-E565743

Eperezolid

Controlled Product

CAS: 165800-04-4

Formula: C₁₈H₂₃FN₄O₅

Color and Shape: Neat

Molecular weight: 394.397

Ref: TR-E565740