CAS 16590-41-3

Naltrexone

Description:

Naltrexone is an opioid antagonist primarily used in the management of opioid dependence and alcohol use disorder. It functions by blocking the effects of opioids at the receptor level, thereby reducing cravings and the euphoric effects associated with opioid use. Naltrexone is a white to off-white crystalline powder that is soluble in water and has a molecular formula of C20H23NO4. Its mechanism of action involves competitive inhibition of the mu-opioid receptors, which helps to prevent relapse in individuals recovering from opioid addiction. The substance is typically administered in oral form or via intramuscular injection, with a long half-life that allows for once-daily dosing in oral formulations or less frequent dosing in injectable forms. Side effects may include nausea, headache, dizziness, and fatigue, but it is generally well-tolerated. Due to its opioid-blocking properties, naltrexone is contraindicated in patients currently using opioids, as it can precipitate withdrawal symptoms. Overall, naltrexone plays a significant role in addiction treatment protocols.

Formula:C₂₀H₂₃NO₄

InChI:InChI=1/C20H23NO4/c22-13-4-3-12-9-15-20(24)6-5-14(23)18-19(20,16(12)17(13)25-18)7-8-21(15)10-11-1-2-11/h3-4,11,15,18,22,24H,1-2,5-10H2/t15-,18+,19?,20-/m1/s1

InChI key:InChIKey=DQCKKXVULJGBQN-XFWGSAIBSA-N

SMILES:O[C@]12[C@@]34C=5C(O[C@]3(C(=O)CC1)[H])=C(O)C=CC5C[C@]2(N(CC6CC6)CC4)[H]

Synonyms:

(1S,5R,13R,17S)-4-(Cyclopropylmethyl)-10,17-dihydroxy-12-oxa-4-azapentacyclo[9.6.1.0~1,13~.0~5,17~.0~7,18~]octadeca-7(18),8,10-trien-14-on
(1S,5R,13R,17S)-4-(cyclopropylmethyl)-10,17-dihydroxy-12-oxa-4-azapentacyclo[9.6.1.0~1,13~.0~5,17~.0~7,18~]octadeca-7(18),8,10-trien-14-one
(5a)-17-(Cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxymorphinan-6-one
(5alpha)-17-(Cyclopropylmethyl)-3,14-dihydroxy-4,5-epoxymorphinan-6-one
1-N-Cyclopropylmethyl-7,8-dihydro-14-hydroxynormorphinone
16590-41-3
Depotrex
En 1639
En 1639A
Morphinan-6-one, 17-(cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxy-, (5α)-
Morphinan-6-one, 17-(cyclopropylmethyl)-4,5α-epoxy-3,14-dihydroxy-
N-Cyclopropylmethylnoroxymorphone
Naltrel
Naltrexon
Naltrexona
Nemexin
ReVia
Trexonil
Um 792
Vivitrex
Vivitrol
Naltrexone Hydrochloride Impurity 1
Naltrexone USP/EP/BP
Naltrexone (200 mg)
trexan
Naltrexone (1.0 mg/mL in Methanol)
Naltrexone Base & HCL
3,14-Dihydroxy-17-(cyclopropylmethyl)-4,5α-epoxymorphinan-6-one
Naltrexone, 1.0 mg/mL
en1939
en1639
Naltrexone trifluoroacetate salt
NALTREXONE10G
Naltrexone (base and/or unspecified salts)
(4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-2,3,4,4a,5,6-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7(7aH)-one
Naltrexone impurty
NaltrexoneBase
NALTREXONE
Naltrexone (base, anhydrous)
celupan
17-(cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxymorphinan-6-one
4,5α-Epoxy-3,14β-dihydroxy-17-(cyclopropylmethyl)morphinan-6-one
C07253
17-(cyclopropylmethyl)-4,5-alpha-epoxy-3,14-dihydroxy-morphinan-6-on
n-cyclopropylmethyl-14-hydroxydihydromorphinone
Naltrexone (controlled) HCl
Naltrexone solution
5-epoxy-3,14-dihydroxy-17-(cyclopropylmethyl)-(5-alpha)-morphinan-6-on
See more synonyms

Purity (%)

100

Found 6 products.

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Naltrexone
CAS:
- 16590-41-3
Alkaloids of opium and their derivatives, salts thereof
Formula:C₂₀H₂₃NO₄
Color and Shape:Tan Off-White Powder
Molecular weight:341.4
Ref: 45-1453504
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Naltrexone
CAS:
- 16590-41-3
Formula:C₂₀H₂₃NO₄
Purity:≥ 98.0%
Color and Shape:White powder
Molecular weight:341.40
Ref: 7W-GP4647
50mg
261.00€
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Naltrexone
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 16590-41-3
Formula:C₂₀H₂₃NO₄
Color and Shape:Neat
Molecular weight:341.40
Ref: 86-MM0233.04
250mg
1,598.00€
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1-Chloro Naltrexone
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 16590-41-3
Formula:C₂₀H₂₂ClNO₄
Color and Shape:Neat
Molecular weight:375.85
Ref: TR-C375265
25mg
3,428.00€
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Naltrexone
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 16590-41-3
Applications Naltrexone is an opioid antagonist shown to reduce the occurrence of addictive behaviours such as eating, smoking and drinking excessively. in addition to curbing drug use it has recently been used in flavor avoidance studies.
References Mannelli, P. et al.: Drug Alc. Dep. 138, 83 (2014); Rotella, F. et al.: 128, 133 (2014);
Formula:C₂₀H₂₃NO₄
Color and Shape:White To Light Beige
Molecular weight:341.4
Ref: TR-N285745
1g
1,528.00€
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100mg
320.00€
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2500mg
2,662.00€
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Naltrexone (1 mg/mL in Methanol)
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 16590-41-3
Formula:C₂₀H₂₃NO₄
Color and Shape:Single Solution
Molecular weight:341.40
Ref: TR-KIT7810
5x1ml
1,022.00€
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