CAS 16595-80-5

Levamisole Hydrochloride

Description:

Levamisole Hydrochloride, with the CAS number 16595-80-5, is a synthetic compound primarily known for its use as an anthelmintic agent in veterinary medicine and as an immunomodulator in humans. It appears as a white to off-white crystalline powder, which is soluble in water and has a slightly bitter taste. The chemical structure of Levamisole features a thiazole ring and an imidazothiazole moiety, contributing to its pharmacological properties. It acts by interfering with the neuromuscular function of parasites, leading to their paralysis and subsequent elimination from the host. In humans, it has been explored for its potential in enhancing immune responses, particularly in cancer therapy and autoimmune diseases. However, its use has diminished due to side effects and the availability of alternative treatments. Levamisole Hydrochloride is typically administered orally or via injection, and its pharmacokinetics involve rapid absorption and metabolism, with a relatively short half-life. Safety and efficacy profiles are essential considerations in its application, particularly in sensitive populations.

Formula: C₁₁H₁₃ClN₂S

InChI: InChI=1/C11H12N2S.ClH/c1-2-4-9(5-3-1)10-8-13-6-7-14-11(13)12-10;/h1-5,10H,6-8H2;1H/t10-;/m1./s1

InChI key: InChIKey=LAZPBGZRMVRFKY-HNCPQSOCSA-N

SMILES: [C@@H]1(CN2C(=N1)SCC2)C3=CC=CC=C3.Cl

Synonyms:

• (-)-(S)-2,3,5,6-tetrahydro-6-phenylimidazo [2,1-b] thiazole monohydrochloride
• (-)-2,3,5,6-Tetrahydro-6-phenylimidazo[2,1-b]thiazole hydrochloride
• (-)-Tetramisole hydrochloride
• (6S)-6-Phenyl-2H,3H,5H,6H-imidazo[2,1-b][1,3]thiazole hydrochloride
• (7S)-7-Phenyl-4-thia-1,6-diazabicyclo[3.3.0]oct-5-ene hydrochloride
• <span class="text-smallcaps">L</span>-Narpenol
• Ascaridil
• Century-Ace
• Citarin L
• Citarinl
• Decaris
• Dekaris
• Ergamisol
• Ergamisole
• Imidazo[2,1-b]thiazole, 2,3,5,6-tetrahydro-6-phenyl-, hydrochloride (1:1), (6S)-
• Imidazo[2,1-b]thiazole, 2,3,5,6-tetrahydro-6-phenyl-, monohydrochloride, (-)-
• Imidazo[2,1-b]thiazole, 2,3,5,6-tetrahydro-6-phenyl-, monohydrochloride, (6S)-
• Imidazo[2,1-b]thiazole,2,3,5,6-tetrahydro-6-phenyl-,monohydrochloride,(S)-
• Kw 2Le-T
• Kw-2-Le-T
• L-2,3,5,6-Tetrahydro-6-phenylimidazo-[2,1-6]-thiazole
• Levacide
• Levadin
• Levamisole HCL
• Levamisole Hcl EP5
• Levasole
• Levomysol hydrochloride
• Meglum
• NSC 177023
• Nemicide
• Nilverm forte
• Niratil
• R 12654
• Ripercol L
• Solaskil
• Spartakon L
• Tramisol
• Tramisole
• l-Tetramisole hydrochloride
• TETRAMISOLE HCL
• LEVAMISOLE HYDROCHLORIDE
• L-(-)-2,3,5,6-TETRAHYDRO-6-PHENYLIMIDAZO (2,1B)THIAZOLE HCL
• L(-)-2,3,5,6-TETRAHYDRO-6-PHENYLIMIDAZO[2,1-B]THIAZOLE HYDROCHLORIDE
• 1-b)thiazole,2,3,5,6-tetrahydro-6-phenyl-,monohydrochloride,l-(-)-imidazo(
• L[-]-2,3,5,6-TETRA-HYDRO-6-PHENYLIMIDAZO[2,1-B]THIAZOLE HYDROCHLORIDE
• TETRAMISOL HYDROCHLORIDE
• 1-b]thiazole,2,3,5,6-tetrahydro-6-phenyl-,monohydrochloride,(S)-Imidazo[2
• LEVAMISOL HYDROCHLORIDE
• 1-b)thiazole,2,3,5,6-tetrahydro-6-phenyl-,monohydrochloride,(s)-imidazo(
• (S)-(-)-6-PHENYL-2,3,5,6-TETRAHYDROIMIDAZO[2,1-B]THIAZOLE HYDROCHLORIDE

Levamisole Hydrochloride

CAS: 16595-80-5

Formula: C₁₁H₁₂N₂S·HCl

Purity: >99.0%(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 240.75

Ref: 3B-T1215

Levamisole Hydrochloride [for Biochemical Research]

CAS: 16595-80-5

Formula: C₁₁H₁₂N₂S·HCl

Purity: >99.0%(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 240.75

Ref: 3B-L0231

Levamisole Hydrochloride 1.0 mg/ml in Methanol (as free base)

CAS: 16595-80-5

Color and Shape: Single Solution

Ref: 61-AMP0706.00-01

LEVAMISOLE HYDROCHLORIDE RS

CAS: 16595-80-5

LEVAMISOLE HYDROCHLORIDE RS

Ref: 41-ICRS070004

Levamisole hydrochloride

CAS: 16595-80-5

Levamisole hydrochloride

Color and Shape: White Crystalline Powder

Ref: 47-212

LEVAMISOLE HYDROCHLORIDE CRS

CAS: 16595-80-5

LEVAMISOLE HYDROCHLORIDE CRS

Color and Shape: Powder

Ref: 41-L0380000

LEVAMISOLE HYDROCHLORIDE FOR SYSTEM SUITABILITY CRS

CAS: 16595-80-5

LEVAMISOLE HYDROCHLORIDE FOR SYSTEM SUITABILITY CRS

Formula: C₁₁H₁₃ClN₂S

Color and Shape: Powder

Molecular weight: 240.7523

Ref: 41-Y0000047

Levamisole Hydrochloride

CAS: 16595-80-5

Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoi

Formula: C₁₁H₁₂N₂S·HCl

Color and Shape: White Powder

Molecular weight: 204.07212

Ref: 45-1359302

Levamisole HCl

CAS: 16595-80-5

Formula: C₁₁H₁₃ClN₂S

Purity: 98%

Color and Shape: Solid

Molecular weight: 240.7523

Ref: IN-DA00388J

Levamisol hydrochloride

CAS: 16595-80-5

Formula: C₁₁H₁₂N₂S·HCl

Purity: ≥ 99.0% (dried basis)

Color and Shape: White crystalline powder

Molecular weight: 240.75

Ref: 7W-GA3670

Levamisole-d4 HCl

CAS: 16595-80-5

Formula: C₁₁H₈D₄N₂S·HCl

Molecular weight: 208.32 36.46

Ref: 4Z-L-9012

Levamisole Hydrochloride

CAS: 16595-80-5

Levamisole Hydrochloride

Purity: 99%

Molecular weight: 240.75g/mol

Ref: 54-OR1030206

Levamisole Hydrochloride

Controlled Product

CAS: 16595-80-5

Formula: C₁₁H₁₂N₂S·ClH

Color and Shape: Neat

Molecular weight: 240.75

Ref: 86-MM0706.00

Levamisol hydrochloride

Controlled Product

CAS: 16595-80-5

Formula: C₁₁H₁₂N₂S·ClH

Color and Shape: Neat

Molecular weight: 240.75

Ref: 04-C14629700

Levamisole Hydrochloride

CAS: 16595-80-5

Color and Shape: Neat

Ref: 61-FOR0706.00

(-)-Tetramisole hydrochloride

CAS: 16595-80-5

Purity: 95.0%

Color and Shape: Solid, White powder

Molecular weight: 240.75

Ref: 10-F094384

Levamisole Hydrochloride

CAS: 16595-80-5

Applications Biological response modifier with anthelmintic activity. Anthelmintic (nematodes); immunomodulator.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Thienpoint, D., et al.: Nature, 209, 1084 (1966), Bullock, M.W., et al.: J. Med. Chem., 11, 169 (1968), Miller, M.J., et al.: Drugs, 20, 122 (1980), Stevenson, H.C., et al.: J. Clin. Oncol., 9, 2052 (1991), Amery, W.K., et al.: Int. J. Immunopharmacol., 14, 481 (1992),

Formula: C₁₁H₁₂N₂S·ClH

Color and Shape: White

Molecular weight: 240.75

Ref: TR-L331100

Levamisole Hydrochloride (1 mg/mL in Methanol)

Controlled Product

CAS: 16595-80-5

Formula: C₁₁H₁₂N₂S·ClH

Color and Shape: Colourless

Molecular weight: 240.75

Ref: TR-KIT8590

Levamisole HCl - Bio-X ™

CAS: 16595-80-5

Levamisole is a synthetic imidazothiazole derivative belonging to the family of anthelmintic drugs. It is a nicotinic acetylcholine receptor (nAChR) agonists that binds to nAChRs on the neuromuscular junctions of parasitic worms, mimicking the action of the neurotransmitter acetylcholine. This excessive stimulation of nAChRs leads to persistent depolarization of muscle cells and spastic paralysis to expel of the worms. Levamisole exhibits broad-spectrum activity against various roundworms, whipworms, hookworms, and threadworms.

Formula: C₁₁H₁₂N₂S·HCl

Purity: Min. 98.0%

Color and Shape: Powder

Molecular weight: 240.75 g/mol

Ref: 3D-BL166245

Levamisole hydrochloride

CAS: 16595-80-5

Levamisole is a synthetic imidazothiazole derivative belonging to the family of anthelmintic drugs. It is a nicotinic acetylcholine receptor (nAChR) agonists that binds to nAChRs on the neuromuscular junctions of parasitic worms, mimicking the action of the neurotransmitter acetylcholine. This excessive stimulation of nAChRs leads to persistent depolarization of muscle cells and spastic paralysis to expel of the worms. Levamisole exhibits broad-spectrum activity against various roundworms, whipworms, hookworms, and threadworms.

Formula: C₁₁H₁₂N₂S·HCl

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 240.75 g/mol

Ref: 3D-FL29670