CAS 16595-80-5
:Levamisole Hydrochloride
Description:
Levamisole Hydrochloride, with the CAS number 16595-80-5, is a synthetic compound primarily known for its use as an anthelmintic agent in veterinary medicine and as an immunomodulator in humans. It appears as a white to off-white crystalline powder, which is soluble in water and has a slightly bitter taste. The chemical structure of Levamisole features a thiazole ring and an imidazothiazole moiety, contributing to its pharmacological properties. It acts by interfering with the neuromuscular function of parasites, leading to their paralysis and subsequent elimination from the host. In humans, it has been explored for its potential in enhancing immune responses, particularly in cancer therapy and autoimmune diseases. However, its use has diminished due to side effects and the availability of alternative treatments. Levamisole Hydrochloride is typically administered orally or via injection, and its pharmacokinetics involve rapid absorption and metabolism, with a relatively short half-life. Safety and efficacy profiles are essential considerations in its application, particularly in sensitive populations.
Formula:C11H13ClN2S
InChI:InChI=1/C11H12N2S.ClH/c1-2-4-9(5-3-1)10-8-13-6-7-14-11(13)12-10;/h1-5,10H,6-8H2;1H/t10-;/m1./s1
InChI key:InChIKey=LAZPBGZRMVRFKY-HNCPQSOCSA-N
SMILES:[C@@H]1(CN2C(=N1)SCC2)C3=CC=CC=C3.Cl
Synonyms:- (-)-(S)-2,3,5,6-tetrahydro-6-phenylimidazo [2,1-b] thiazole monohydrochloride
- (-)-2,3,5,6-Tetrahydro-6-phenylimidazo[2,1-b]thiazole hydrochloride
- (-)-Tetramisole hydrochloride
- (6S)-6-Phenyl-2H,3H,5H,6H-imidazo[2,1-b][1,3]thiazole hydrochloride
- (7S)-7-Phenyl-4-thia-1,6-diazabicyclo[3.3.0]oct-5-ene hydrochloride
- <span class="text-smallcaps">L</span>-Narpenol
- Ascaridil
- Century-Ace
- Citarin L
- Citarinl
- Decaris
- Dekaris
- Ergamisol
- Ergamisole
- Imidazo[2,1-b]thiazole, 2,3,5,6-tetrahydro-6-phenyl-, hydrochloride (1:1), (6S)-
- Imidazo[2,1-b]thiazole, 2,3,5,6-tetrahydro-6-phenyl-, monohydrochloride, (-)-
- Imidazo[2,1-b]thiazole, 2,3,5,6-tetrahydro-6-phenyl-, monohydrochloride, (6S)-
- Imidazo[2,1-b]thiazole,2,3,5,6-tetrahydro-6-phenyl-,monohydrochloride,(S)-
- Kw 2Le-T
- Kw-2-Le-T
- L-2,3,5,6-Tetrahydro-6-phenylimidazo-[2,1-6]-thiazole
- Levacide
- Levadin
- Levamisole HCL
- Levamisole Hcl EP5
- Levasole
- Levomysol hydrochloride
- Meglum
- NSC 177023
- Nemicide
- Nilverm forte
- Niratil
- R 12654
- Ripercol L
- Solaskil
- Spartakon L
- Tramisol
- Tramisole
- l-Tetramisole hydrochloride
- TETRAMISOLE HCL
- LEVAMISOLE HYDROCHLORIDE
- L-(-)-2,3,5,6-TETRAHYDRO-6-PHENYLIMIDAZO (2,1B)THIAZOLE HCL
- L(-)-2,3,5,6-TETRAHYDRO-6-PHENYLIMIDAZO[2,1-B]THIAZOLE HYDROCHLORIDE
- 1-b)thiazole,2,3,5,6-tetrahydro-6-phenyl-,monohydrochloride,l-(-)-imidazo(
- L[-]-2,3,5,6-TETRA-HYDRO-6-PHENYLIMIDAZO[2,1-B]THIAZOLE HYDROCHLORIDE
- TETRAMISOL HYDROCHLORIDE
- 1-b]thiazole,2,3,5,6-tetrahydro-6-phenyl-,monohydrochloride,(S)-Imidazo[2
- LEVAMISOL HYDROCHLORIDE
- 1-b)thiazole,2,3,5,6-tetrahydro-6-phenyl-,monohydrochloride,(s)-imidazo(
- (S)-(-)-6-PHENYL-2,3,5,6-TETRAHYDROIMIDAZO[2,1-B]THIAZOLE HYDROCHLORIDE
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Levamisole Hydrochloride [for Biochemical Research]
CAS:Formula:C11H12N2S·HClPurity:>99.0%(T)Color and Shape:White to Almost white powder to crystalMolecular weight:240.75LEVAMISOLE HYDROCHLORIDE FOR SYSTEM SUITABILITY CRS
CAS:LEVAMISOLE HYDROCHLORIDE FOR SYSTEM SUITABILITY CRSFormula:C11H13ClN2SColor and Shape:PowderMolecular weight:240.7523Levamisole Hydrochloride
CAS:Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoiFormula:C11H12N2S·HClColor and Shape:White PowderMolecular weight:204.07212Levamisole Hydrochloride
CAS:Levamisole HydrochlorideFormula:C11H13ClN2SPurity:99%Molecular weight:240.75Levamisol hydrochloride
CAS:Formula:C11H12N2S·HClPurity:≥ 99.0% (dried basis)Color and Shape:White crystalline powderMolecular weight:240.75Levamisol hydrochloride
CAS:Controlled ProductFormula:C11H12N2S·ClHColor and Shape:NeatMolecular weight:240.75Levamisole Hydrochloride
CAS:Formula:C11H12N2S·HClPurity:>99.0%(T)Color and Shape:White to Almost white powder to crystalMolecular weight:240.75Levamisole Hydrochloride
CAS:Controlled ProductFormula:C11H12N2S·ClHColor and Shape:WhiteMolecular weight:240.75(-)-Tetramisole hydrochloride
CAS:Purity:95.0%Color and Shape:Solid, White powderMolecular weight:240.75Levamisole Hydrochloride
CAS:Applications Biological response modifier with anthelmintic activity. Anthelmintic (nematodes); immunomodulator.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Thienpoint, D., et al.: Nature, 209, 1084 (1966), Bullock, M.W., et al.: J. Med. Chem., 11, 169 (1968), Miller, M.J., et al.: Drugs, 20, 122 (1980), Stevenson, H.C., et al.: J. Clin. Oncol., 9, 2052 (1991), Amery, W.K., et al.: Int. J. Immunopharmacol., 14, 481 (1992),Formula:C11H12N2S·ClHColor and Shape:NeatMolecular weight:240.75Levamisole HCl - Bio-X ™
CAS:Levamisole is a synthetic imidazothiazole derivative belonging to the family of anthelmintic drugs. It is a nicotinic acetylcholine receptor (nAChR) agonists that binds to nAChRs on the neuromuscular junctions of parasitic worms, mimicking the action of the neurotransmitter acetylcholine. This excessive stimulation of nAChRs leads to persistent depolarization of muscle cells and spastic paralysis to expel of the worms. Levamisole exhibits broad-spectrum activity against various roundworms, whipworms, hookworms, and threadworms.
Formula:C11H12N2S·HClPurity:Min. 98.0%Color and Shape:PowderMolecular weight:240.75 g/molLevamisole hydrochloride
CAS:Levamisole is a synthetic imidazothiazole derivative belonging to the family of anthelmintic drugs. It is a nicotinic acetylcholine receptor (nAChR) agonists that binds to nAChRs on the neuromuscular junctions of parasitic worms, mimicking the action of the neurotransmitter acetylcholine. This excessive stimulation of nAChRs leads to persistent depolarization of muscle cells and spastic paralysis to expel of the worms. Levamisole exhibits broad-spectrum activity against various roundworms, whipworms, hookworms, and threadworms.Formula:C11H12N2S·HClPurity:Min. 95%Color and Shape:White PowderMolecular weight:240.75 g/mol
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