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CAS 16754-80-6

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6-Chloro-7-deazapurine-b-D-riboside

Description:
6-Chloro-7-deazapurine-β-D-riboside is a nucleoside analog characterized by its structural components, which include a purine base modified by the presence of a chlorine atom and a ribose sugar. This compound is notable for its potential biological activity, particularly in the context of antiviral and anticancer research, as it can interfere with nucleic acid synthesis. The presence of the 7-deaza substitution in the purine ring enhances its stability and alters its interaction with nucleic acid targets. The β-D-riboside configuration indicates that the ribose sugar is in the β-anomeric form, which is crucial for its biological function. This compound is typically soluble in polar solvents and may exhibit moderate to high stability under physiological conditions. Its unique structure allows it to mimic natural nucleosides, making it a valuable tool in biochemical studies and drug development. As with many nucleoside analogs, its pharmacological properties and mechanisms of action are subjects of ongoing research.
Formula:C11H12ClN3O4
InChI:InChI=1/C11H12ClN3O4/c12-9-5-1-2-15(10(5)14-4-13-9)11-8(18)7(17)6(3-16)19-11/h1-2,4,6-8,11,16-18H,3H2
SMILES:c1cn(c2c1c(Cl)ncn2)C1C(C(C(CO)O1)O)O
Synonyms:
  • 4-Chloro-7-(D-ribofuranosyl)pyrrolo[2,3-d]pyrimidine
  • 6-Chloro-9-(D-ribofuranosyl)-7-deazapurine
  • 6-Deamino-6-chlorotubercidin
  • Nsc 101161
  • 6-Chloro-7-deaza-9-(b-D-ribofuranosyl)purine
  • 6-Chloro-7-Deazapurine-Ss-D-Riboside
  • 4-chloro-7-pentofuranosyl-7H-pyrrolo[2,3-d]pyrimidine
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