CAS 1676-90-0

boc-L-aspartic acid 4-tert-butyl ester

Description:

Boc-L-aspartic acid 4-tert-butyl ester is a derivative of aspartic acid, characterized by the presence of a tert-butyl ester group and a Boc (tert-butyloxycarbonyl) protecting group on the amino functionality. This compound is typically used in peptide synthesis and organic chemistry as a protected form of aspartic acid, facilitating the selective reaction of functional groups. It is a white to off-white solid that is soluble in organic solvents such as dichloromethane and dimethyl sulfoxide, but less soluble in water. The Boc group provides stability and protects the amine from unwanted reactions during synthesis, while the tert-butyl ester enhances lipophilicity, aiding in the purification and handling of the compound. The compound's structure allows for the easy removal of the Boc group under mild acidic conditions, regenerating the free amine for further reactions. Overall, Boc-L-aspartic acid 4-tert-butyl ester is a valuable intermediate in the synthesis of peptides and other bioactive molecules.

Formula: C₁₃H₂₃NO₆

InChI: InChI=1/C13H23NO6/c1-12(2,3)19-9(15)7-8(10(16)17)14-11(18)20-13(4,5)6/h8H,7H2,1-6H3,(H,14,18)(H,16,17)/t8-/m0/s1

SMILES: CC(C)(C)OC(=O)C[C@@H](C(=O)O)N=C(O)OC(C)(C)C

Synonyms:

• Boc-Asp(OtBu)-OH
• N-(tert-Butoxycarbonyl)-L-aspartic acid β-tert butyl ester
• (2S)-4-tert-butoxy-2-[(tert-butoxycarbonyl)amino]-4-oxobutanoic acid (non-preferred name)
• Boc-Asp(OBut)
• BOC-ASP(OBUT)-OH
• N-ALPHA-T-BOC-L-ASPARTIC ACID BETA-T-BUTYL ESTER
• BOC-L-ASPARTIC ACID-BETA-T-BUTYL ESTER
• BOC-ASPARTIC ACID(OTBU)-OH
• N-ALPHA-T-BUTOXYCARBONYL-L-ASPARTIC ACID-4-T-BUTYL ESTER
• BOC-L-ASPARTIC ACID 4-TERT-BUTYL ESTER
• N-ALPHA-T-BUTOXYCARBONYL-L-ASPARTIC ACID-BETA-T-BUTYL ESTER
• N-ALPHA-TERT-BUTYLOXYCARBONYL-L-ASPARTIC ACID BETA-TERT-BUTYL ESTER
• BOC-L-ASP(OTBU)-OH
• BOC-ASP-OTBU
• BOC-L-ASP(TBU)-OH

4-tert-Butyl N-(tert-Butoxycarbonyl)-L-aspartate

CAS: 1676-90-0

Formula: C₁₃H₂₃NO₆

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 289.33

Ref: 3B-B3935

N-Boc-L-aspartic acid 4-tert-butyl ester, 98%

CAS: 1676-90-0

It is used in the preparation of highly selective thrombin inhibitors. Also used in the preparation of thiopeptides and thioacylating agents. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to

Formula: C₁₃H₂₃NO₆

Purity: 98%

Molecular weight: 289.33

Ref: 02-H63554

tert-Butyloxycarbonyl-L-aspartic acid 4-tert-butyl ester

CAS: 1676-90-0

Formula: C₁₃H₂₃NO₆

Purity: 97%

Color and Shape: Solid

Molecular weight: 289.3248

Ref: IN-DA0034K0

Boc-Asp(OtBu)-OH

CAS: 1676-90-0

Molecular weight: 289.32

Ref: 7W-GM1038

Boc-Asp(Otbu)-OH

CAS: 1676-90-0

Boc-Asp(Otbu)-OH

Formula: C₁₃H₂₃NO₆

Purity: >98%

Molecular weight: 289.32

Ref: 54-OR1012479

Boc-Asp(OtBu)-OH

CAS: 1676-90-0

M03268 - Boc-Asp(OtBu)-OH

Formula: C₁₃H₂₃NO₆

Purity: 97%

Color and Shape: Solid, Beige powder

Molecular weight: 289.328

Ref: 10-M03268

Boc-Asp(OtBu)-OH

CAS: 1676-90-0

Boc-Asp(OtBu)-OH

Formula: C₁₃H₂₃NO₆

Purity: 97%

Molecular weight: 289.32

Ref: IN-DG18792

N-tert-Butyloxycarbonyl-L-aspartic Acid b-tert-Butyl Ester

Controlled Product

CAS: 1676-90-0

Formula: C₁₃H₂₃NO₆

Color and Shape: Neat

Molecular weight: 289.32

Ref: TR-B809200

Boc-L-aspartic acid 4-tert-butyl ester

CAS: 1676-90-0

Boc-L-aspartic acid 4-tert-butyl ester is a synthetic aminoacylase that is used in the synthesis of ergosterol. It is an efficient and economical reagent for the preparation of esters of aspartic acid, which are used in fungal antifungal agents. Boc-L-aspartic acid 4-tert-butyl ester has been shown to have various physiological functions, including the ability to inhibit ergosterol synthesis by inhibiting the enzyme polymeric ergosterol synthase in fungi. This compound can also be used to synthesize n-substituted aspartates.

Formula: C₁₃H₂₃NO₆

Purity: Min. 95 Area-%

Color and Shape: Powder

Molecular weight: 289.32 g/mol

Ref: 3D-FB37881

Boc-Asp(OtBu)-OH

CAS: 1676-90-0

Bachem ID: 4025872.

Formula: C₁₃H₂₃NO₆

Purity: > 99%

Color and Shape: White Powder

Molecular weight: 289.33

Ref: 01-4025872