CAS 1677668-27-7

Formula: C23H16ClN3O4

InChI: InChI=1S/C23H16ClN3O4/c24-16-4-1-3-14(12-5-6-12)18(16)20(29)22-26-19(21-25-9-2-10-27(21)22)13-7-8-15(23(30)31)17(28)11-13/h1-4,7-12,28H,5-6H2,(H,30,31)

InChI key: GIYKJPISDNWSJD-UHFFFAOYSA-N

SMILES: C1CC1C2=C(C(=CC=C2)Cl)C(=O)C3=NC(=C4N3C=CC=N4)C5=CC(=C(C=C5)C(=O)O)O

GNE-6468

CAS: 1677668-27-7

GNE-6468

Formula: C₂₃H₁₆ClN₃O₄

Purity: 98.04%

Molecular weight: 433.84

Ref: 54-OR1131032

GNE-6468

CAS: 1677668-27-7

Formula: C₂₃H₁₆ClN₃O₄

Purity: 98.04%

Molecular weight: 433.8438

Ref: IN-DA01FVJ6

GNE-6468

CAS: 1677668-27-7

GNE-6468 is a synthetic retinoic acid molecule that has been shown to be an orthosteric agonist of nuclear receptors. This drug binds to the nuclear receptor RARα and induces the expression of genes involved in inflammatory and autoimmune diseases. GNE-6468 has been shown to have a variety of biological effects, including modulation of interleukin production, regulation of gene expression, and induction of apoptosis. GNE-6468 also has chemotherapeutic activity against primary cells derived from multiple myeloma patients.

Formula: C₂₃H₁₆ClN₃O₄

Purity: Min. 95%

Molecular weight: 433.8 g/mol

Ref: 3D-CSC66827

GNE-6468

CAS: 1677668-27-7

GNE-6468 is a potent and selective agonist of RORγ(RORc) (EC50: 13 nM for HEK-293 cell).

Formula: C₂₃H₁₆ClN₃O₄

Purity: 98.68% - 99.73%

Color and Shape: Solid

Molecular weight: 433.844

Ref: TM-T15404