CAS 16839-98-8: Noratropine

Description: Noratropine, with the CAS number 16839-98-8, is a chemical compound that belongs to the class of tropane alkaloids. It is structurally related to atropine and scopolamine, which are well-known tropane derivatives. Noratropine is characterized by its bicyclic structure, which includes a nitrogen atom in a six-membered ring, contributing to its pharmacological properties. This compound exhibits anticholinergic activity, meaning it can inhibit the action of acetylcholine at muscarinic receptors, leading to effects such as reduced secretions and muscle relaxation. Noratropine is of interest in medicinal chemistry due to its potential applications in treating various conditions, including motion sickness and muscle spasms. However, its specific therapeutic uses and safety profile require further investigation. As with many alkaloids, the biological activity of noratropine can be influenced by its stereochemistry and the presence of functional groups, making it a subject of study in both pharmacology and organic synthesis.

Formula: C₁₆H₂₁NO₃

InChI: InChI=1/C16H21NO3/c18-10-15(11-4-2-1-3-5-11)16(19)20-14-8-12-6-7-13(9-14)17-12/h1-5,12-15,17-18H,6-10H2/t12-,13+,14+,15?

InChI key: InChIKey=ATKYNAZQGVYHIB-MCOXGKPRNA-N

SMILES: O=C(OC1CC2NC(CC2)C1)C(C=3C=CC=CC3)CO

Synonyms:

• 1α<span class="text-smallcaps">H</smallcap>,5α<smallcap>H</span>-Nortropan-3α-ol, (±)-tropate (ester)
• 2-[3-(8-Azabicyclo[3.2.1]Oct-3-Yl)Phenyl]-3-Hydroxypropanoic Acid
• 8-Azabicyclo[3.2.1]Oct-3-Yl 3-Hydroxy-2-Phenylpropanoate
• 8-azabicyclo[3.2.1]oct-3-yl (2S)-3-hydroxy-2-phenylpropanoate
• Benzeneacetic acid, alpha-(hydroxymethyl)-, (3-endo)-8-azabicyclo(3.2.1)oct-3-yl ester
• Benzeneacetic acid, alpha-(hydroxymethyl)-, 8-azabicyclo(3.2.1)oct-3-yl ester, endo-(+-)-
• Benzeneacetic acid, α-(hydroxymethyl)-, (3-endo)-8-azabicyclo[3.2.1]oct-3-yl ester
• Benzeneacetic acid, α-(hydroxymethyl)-, 8-azabicyclo[3.2.1]oct-3-yl ester, endo-
• N-Demethylatropine
• Norhyoscyamine
• 1αH,5αH-Nortropan-3α-ol, (±)-tropate (ester)
• Noratropine

Benzeneacetic acid, α-(hydroxymethyl)-, (3-endo)-8-azabicyclo[3.2.1]oct-3-yl ester

CAS: 16839-98-8

• Formula: C₁₆H₂₁NO₃
• Molecular weight: 275.3428

Atropine EP Impurity B (Noratropine)

CAS: 16839-98-8

• Formula: C₁₆H₂₁NO₃
• Color and Shape: White To Off-White Solid
• Molecular weight: 275.35

Noratropine

CAS: 16839-98-8

Natural alkaloid

• Formula: C₁₆H₂₁NO₃
• Purity: ≥ 95.0 % (HPLC)
• Color and Shape: Powder
• Molecular weight: 275.34

Noratropine

CAS: 16839-98-8

Noratropine is a drug that belongs to the group of anticholinergic drugs. It is used …

• Formula: C₁₆H₂₁NO₃
• Purity: Min. 95%
• Molecular weight: 275.34 g/mol