CAS 168425-64-7

2-(morpholin-4-yl)-4H-pyrimido[2,1-a]isoquinolin-4-one

Description:

2-(Morpholin-4-yl)-4H-pyrimido[2,1-a]isoquinolin-4-one is a heterocyclic compound characterized by its complex structure, which includes a pyrimidoisoquinoline framework fused with a morpholine moiety. This compound typically exhibits properties such as moderate solubility in polar solvents and potential bioactivity, making it of interest in medicinal chemistry. The presence of the morpholine ring contributes to its ability to interact with biological targets, potentially influencing its pharmacological profile. The compound may also display various functional groups that can participate in hydrogen bonding and other intermolecular interactions, enhancing its reactivity and binding affinity. Its unique structure suggests potential applications in drug development, particularly in targeting specific biological pathways. Additionally, the compound's stability and reactivity can be influenced by environmental factors such as pH and temperature, which are important considerations in both laboratory and therapeutic contexts. Overall, 2-(morpholin-4-yl)-4H-pyrimido[2,1-a]isoquinolin-4-one represents a significant area of interest for researchers exploring novel therapeutic agents.

Formula: C₁₆H₁₅N₃O₂

InChI: InChI=1/C16H15N3O2/c20-15-11-14(18-7-9-21-10-8-18)17-16-13-4-2-1-3-12(13)5-6-19(15)16/h1-6,11H,7-10H2

InChI key: BVRDQVRQVGRNHG-UHFFFAOYSA-N

SMILES: c1ccc2c(c1)ccn1c(=O)cc(nc21)N1CCOCC1

Synonyms:

• 4H-Pyrimido[2,1-a]isoquinolin-4-one, 2-(4-morpholinyl)-
• Compound 401
• 2-(Morpholin-4-yl)-4H-pyrimido[2,1-a]isoquinolin-4-one
• Morpholino a
• -pyrimido[2,1-
• ]isoquinolin-4-one
• 2-Morpholino-4H-pyrimido[2,1-a]isoquinolin-4-one&gt
• 2-Morpholino-4
• 2-(4-Morpholinyl)-4H-pyrimido[2,1-a]isoquinolin-4-one
• Compound 401, >=98%
• 2-Morpholino-4H-pyrimido[2,1-a]isoquinolin-4-one
• CS-315
• a
• 2-(Morpholin-4-yl)pyrimido[2,1-a]isoquinolin-4-one
• COMPOUND401;COMPOUND-401

2-Morpholino-4H-pyrimido[2,1-a]isoquinolin-4-one

CAS: 168425-64-7

Formula: C₁₆H₁₅N₃O₂

Purity: >98.0%(GC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 281.32

Ref: 3B-M2537

2-Morpholino-4H-Pyrimido[2,1-A]Isoquinolin-4-One

CAS: 168425-64-7

2-Morpholino-4H-Pyrimido[2,1-A]Isoquinolin-4-One

Formula: C₁₆H₁₅N₃O₂

Purity: >98%

Molecular weight: 281.32

Ref: 54-OR1025735

Compound 401

CAS: 168425-64-7

Formula: C₁₆H₁₅N₃O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 281.3092

Ref: IN-DA001Y1Q

Compound 401

CAS: 168425-64-7

Compound 401

Formula: C₁₆H₁₅N₃O₂

Purity: ≥98%

Molecular weight: 281.31

Ref: 54-BUP13097

Compound 401

CAS: 168425-64-7

Compound 401 (2-morpholino-4H-pyrimido[2,1-a]isoquinolin-4-one) is a synthetic DNA-PK inhibitor (IC50 = 0.28 μM) that also targets mTOR but not PI3K.

Formula: C₁₆H₁₅N₃O₂

Purity: 99.55% - 99.73%

Color and Shape: White Solid

Molecular weight: 281.31

Ref: TM-T3586

Compound 401

CAS: 168425-64-7

Purity: ≥98%(HPLC)

Molecular weight: 281.116

Ref: 10-F865767