CAS 168427-74-5

(2R,3S,4S,5R)-5-(6-aminopurin-9-yl)-2-(hydroxymethyl)-4-(2-methoxyethoxy)tetrahydrofuran-3-ol

Description:

The chemical substance known as "(2R,3S,4S,5R)-5-(6-aminopurin-9-yl)-2-(hydroxymethyl)-4-(2-methoxyethoxy)tetrahydrofuran-3-ol," with the CAS number 168427-74-5, is a complex organic compound characterized by its tetrahydrofuran ring structure, which incorporates multiple functional groups. This compound features a hydroxymethyl group and a methoxyethoxy substituent, contributing to its solubility and reactivity. The presence of the 6-aminopurine moiety indicates potential biological activity, as purines are fundamental components of nucleic acids and play crucial roles in cellular processes. The stereochemistry, denoted by the (2R,3S,4S,5R) configuration, suggests specific spatial arrangements of atoms that can influence the compound's interactions with biological targets. This compound may be of interest in medicinal chemistry and biochemistry, particularly in the development of nucleoside analogs or other therapeutic agents. Its unique structural features and potential biological implications warrant further investigation for applications in drug development or biochemical research.

Formula: C₁₃H₁₉N₅O₅

InChI: InChI=1/C13H19N5O5/c1-21-2-3-22-10-9(20)7(4-19)23-13(10)18-6-17-8-11(14)15-5-16-12(8)18/h5-7,9-10,13,19-20H,2-4H2,1H3,(H2,14,15,16)/t7-,9+,10+,13-/m1/s1

Synonyms:

• 2'-O-(2-Methoxyethyl)-adenosine
• 2'-O-Moe-Adenosine
• 2'-O-Methoxyethyl-adenosine
• 2'-O-MOE-A
• (2R,3R,4R,5R)-5-(6-Amino-9H-purin-9-yl)-2-(hydroxy-methyl)-4-(2-methoxyethoxy)tetrahydrofuran-3-o
• (2R,3R,4R,5R)-5-(6-Amino-9H-purin-9-yl)-2-(hydroxymethyl)-4-(2-methoxyethoxy)tetrahydrofuran-3-ol, >97%
• (2R,3S,4S,5R)-5-(6-aminopurin-9-yl)-2-(hydroxymethyl)-4-(2-methoxyethoxy)tetrahydrofuran-3-ol
• 2'-O-MOE-rA
• (2R,3R,4R,5R)-5-(6-AMino-9H-purin-9-yl)-2-(hydroxyMethyl)-4-(2-Methoxyethoxy)tetrahydrofuran-3-ol
• 2'-O-MOE-ADENOSINE USP/EP/BP
• (2R,3R,4R,5R)-5-(6-Amino-9H-purin-9-yl)-2-(hydroxy-methyl)-4-(2-methoxyethoxy)tetrahydrofuran-
• 2'-O-MOE-Ar

Adenosine, 2'-O-(2-methoxyethyl)-

CAS: 168427-74-5

Formula: C₁₃H₁₉N₅O₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 325.3205

Ref: IN-DA001Y2O

(2R,3R,4R,5R)-5-(6-Amino-9H-Purin-9-Yl)-2-(Hydroxymethyl)-4-(2-Methoxyethoxy)Tetrahydrofuran-3-Ol

CAS: 168427-74-5

(2R,3R,4R,5R)-5-(6-Amino-9H-Purin-9-Yl)-2-(Hydroxymethyl)-4-(2-Methoxyethoxy)Tetrahydrofuran-3-Ol

Formula: C₁₃H₁₉N₅O₅

Purity: 98%

Molecular weight: 325.32

Ref: 54-OR1007974

2''-O-(2-Methoxyethyl)adenosine

CAS: 168427-74-5

Ref: 7W-GC3996

2'-O-(2-Methoxyethyl)adenosine

CAS: 168427-74-5

2'-O-(2-Methoxyethyl)adenosine

Formula: C₁₃H₁₉N₅O₅

Purity: ≥98%

Molecular weight: 325.32

Ref: 54-BUP17027

2'-O-(2-Methoxyethyl)adenosine

CAS: 168427-74-5

Formula: C₁₃H₁₉N₅O₅

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 325.33

Ref: 3B-M3942

2'-O-(2-Methoxyethyl)adenosine

CAS: 168427-74-5

2'-O-(2-Methoxyethyl)adenosine is a nucleoside analog used to improve RNA target affinity and nuclease resistance of therapeutic oligonucleotides in preclin.

Formula: C₁₃H₁₉N₅O₅

Purity: 99.35%

Color and Shape: White Solid

Molecular weight: 325.32

Ref: TM-TNU0047

2'-O-(2-Methoxyethyl)adenosine

CAS: 168427-74-5

2'-O-(2-Methoxyethyl)adenosine is a nucleoside derivative that is produced by the methylation of 2'-deoxyadenosine. It is used in organic synthesis as a reagent for the alkylation of aromatic hydrocarbons and as an intermediate in the synthesis of purines. The product can be isolated with yields of 78% or greater, depending on reaction conditions and purification methods. Isomeric purity can be achieved with high purity (>99%) by recrystallization from water or ethanol. The compound has a number of physical properties that are similar to those of adenosine, including boiling point, melting point, density, and refractive index. The molecule also has two chiral centers at C2 and C4 that contribute to its isomeric nature. Adenosine is found in human connective tissue cells, where it plays a role in cell metabolism by regulating the production of RNA and DNA.

Formula: C₁₃H₁₉N₅O₅

Purity: Min. 95%

Color and Shape: White Off-White Powder

Molecular weight: 325.32 g/mol

Ref: 3D-NM16784

2′-O-(2-Methoxyethyl)adenosine

CAS: 168427-74-5

(2R,3R,4R,5R)-5-(6-Amino-9H-purin-9-yl)-2-(hydroxymethyl)-4-(2-methoxyethoxy)tetrahydrofuran-3-ol

Formula: C₁₃H₁₉N₅O₅

Purity: 98%

Molecular weight: 325.32

Ref: IN-DG234548

(2R,3R,4R,5R)-5-(6-Amino-9H-purin-9-yl)-2-(hydroxymethyl)-4-(2-methoxyethoxy)tetrahydrofuran-3-ol

CAS: 168427-74-5

Formula: C₁₃H₁₉N₅O₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 325.325

Ref: 10-F229458

2'-O-(2-Methoxyethyl)adenosine

Controlled Product

CAS: 168427-74-5

Applications A adenosine derivative as building blocks for cross-linking oligonucleotides.
References Martin, P., et al.: Helv. Chim. Acta, 78, 486 (1995),

Formula: C₁₃H₁₉N₅O₅

Color and Shape: Neat

Molecular weight: 325.32

Ref: TR-M262565