CAS 16941-32-5

glucagon

Description:

Glucagon is a peptide hormone produced by the alpha cells of the pancreas, primarily involved in glucose metabolism. It is composed of 29 amino acids and plays a crucial role in increasing blood glucose levels by promoting glycogenolysis and gluconeogenesis in the liver. Glucagon is typically released in response to low blood sugar levels, acting as a counter-regulatory hormone to insulin. Its structure includes a single chain of amino acids with specific functional groups that facilitate its biological activity. The CAS number 16941-32-5 identifies glucagon in chemical databases, ensuring precise communication regarding this substance. In therapeutic contexts, glucagon is used as a medication to treat severe hypoglycemia and is administered via injection. It is also utilized in diagnostic procedures, such as in imaging studies of the gastrointestinal tract. Overall, glucagon is essential for maintaining glucose homeostasis and is a key player in metabolic regulation.

Formula: C₁₅₃H₂₂₅N₄₃O₄₉S

InChI: InChI=1/C153H225N43O49S/c1-72(2)52-97(133(226)176-96(47-51-246-11)132(225)184-104(60-115(159)209)143(236)196-123(78(10)203)151(244)245)179-137(230)103(58-83-64-167-89-29-19-18-28-87(83)89)183-131(224)95(43-46-114(158)208)177-148(241)120(74(5)6)194-141(234)101(54-79-24-14-12-15-25-79)182-138(231)105(61-117(211)212)185-130(223)94(42-45-113(157)207)171-124(217)75(7)170-127(220)91(31-22-49-165-152(160)161)172-128(221)92(32-23-50-166-153(162)163)174-146(239)110(69-199)191-140(233)107(63-119(215)216)186-134(227)98(53-73(3)4)178-135(228)99(56-81-33-37-85(204)38-34-81)180-129(222)90(30-20-21-48-154)173-145(238)109(68-198)190-136(229)100(57-82-35-39-86(205)40-36-82)181-139(232)106(62-118(213)214)187-147(240)111(70-200)192-150(243)122(77(9)202)195-142(235)102(55-80-26-16-13-17-27-80)188-149(242)121(76(8)201)193-116(210)66-168-126(219)93(41-44-112(156)206)175-144(237)108(67-197)189-125(218)88(155)59-84-65-164-71-169-84/h12-19,24-29,33-40,64-65,71-78,88,90-111,120-123,167,197-205H,20-23,30-32,41-63,66-70,154-155H2,1-11H3,(H2,156,206)(H2,157,207)(H2,158,208)(H2,159,209)(H,164,169)(H,168,219)(H,170,220)(H,171,217)(H,172,221)(H,173,238)(H,174,239)(H,175,237)(H,176,226)(H,177,241)(H,178,228)(H,179,230)(H,180,222)(H,181,232)(H,182,231)(H,183,224)(H,184,225)(H,185,223)(H,186,227)(H,187,240)(H,188,242)(H,189,218)(H,190,229)(H,191,233)(H,192,243)(H,193,210)(H,194,234)(H,195,235)(H,196,236)(H,211,212)(H,213,214)(H,215,216)(H,244,245)(H4,160,161,165)(H4,162,163,166)/t75-,76+,77+,78+,88-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,120-,121-,122-,123-/m0/s1

InChI key: MASNOZXLGMXCHN-ZLPAWPGGSA-N

SMILES: C[C@H]([C@@H](C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC2=CC=C(C=C2)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC3=CC=C(C=C3)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC4=CC=CC=C4)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC5=CNC6=CC=CC=C65)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H]([C@@H](C)O)C(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)N)NC(=O)[C@H](CO)NC(=O)[C@H](CC7=CN=CN7)N)O

Synonyms:

• Glucagon (1-29) (human, bovine, porcine)
• Glucagon, human recombinant
• H-His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr-OH
• L-histidyl-L-seryl-L-glutaminylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-alpha-aspartyl-L-tyrosyl-L-seryl-L-lysyl-L-tyrosyl-L-leucyl-L-alpha-aspartyl-L-seryl-L-arginyl-L-arginyl-L-alanyl-L-glutaminyl-L-alpha-aspartyl-L-phenylalanyl-L-valyl-L-glutaminyl-L-tryptophyl-L-leucyl-L-methionyl-L-asparaginyl-L-threonine
• Glucagon Hydrochloride(Human)

Glucagon (1-29) (human, rat, porcine)

CAS: 16941-32-5

Bachem ID: 4088814.

Formula: C₁₅₃H₂₂₅N₄₃O₄₉S

Purity: 96.4%

Color and Shape: White Lyophilisate

Molecular weight: 3482.8

Ref: 01-4088814

Glucagon (1-29) (human, rat, porcine)

CAS: 16941-32-5

Glucagon is a 29 amino acid containing peptide hormone processed from proglucagon. As a counterregulatory hormone for insulin, glucagon plays a critical role in maintaining glucose homeostasis in vivo in both animals and humans. Not surprisingly, glucagon and glucagon receptor have been pursued extensively as potential targets for the therapeutic treatment of diabetes. As Aβ peptides and IAPP, glucacon tends to form gel-like fibrillar aggregates. These fibrils were found to be toxic through the activation of apoptotic signaling pathways. Hence the aggregation behavior of glucagon has been studied extensively.

Formula: C₁₅₃H₂₂₅N₄₃O₄₉S

Purity: 100.0%

Color and Shape: White Powder

Molecular weight: 3482.8

Ref: 01-4033017

HUMAN GLUCAGON CRS

CAS: 16941-32-5

HUMAN GLUCAGON CRS

Formula: C₁₅₃H₂₂₅N₄₃O₄₉S

Molecular weight: 3482.747

Ref: 41-Y0000191

Glucagon (HUMAN)

CAS: 16941-32-5

Polypeptide, protein and glycoprotein hormones, their derivatives and structural analogues, nesoi

Formula: C₁₅₃H₂₂₅N₄₃O₄₉S

Color and Shape: White Powder

Molecular weight: 3480.6157

Ref: 45-1294036

Glucagon

CAS: 16941-32-5

Formula: C₁₅₃H₂₂₅N₄₃O₄₉S

Purity: 99%

Color and Shape: Solid

Molecular weight: 3482.7473

Ref: IN-DA0039VM

Glucagon

CAS: 16941-32-5

Formula: C₁₅₃H₂₂₅N₄₃O₄₉S

Purity: (HPLC) ≥ 95.0%

Color and Shape: White powder

Molecular weight: 3482.75

Ref: 7W-GX2829

Glucagon

CAS: 16941-32-5

Formula: C₁₅₃H₂₂₅N₄₃O₄₉S

Molecular weight: 3482.80

Ref: 4Z-PG-194007

Glucagon PentaHCl

CAS: 16941-32-5

Formula: C₁₅₃H₂₂₅N₄₃O₄₉S·5HCl

Molecular weight: 3482.80 5*36.46

Ref: 4Z-PG-194012

Glucagon Hydrochlide

CAS: 16941-32-5

Formula: C₁₅₃H₂₂₅N₄₃O₄₉S

Purity: 95%~99%

Color and Shape: White to Off-white Powder

Molecular weight: 3482.75

Ref: BP-BPPG036

Glucagon (1-29), bovine, human, porcine

CAS: 16941-32-5

Corynoxine B (Cory B) is a naturally occurring alkaloid isolated from Uncaria rhynchophylla (Miq. ) and is an autophagy inducer.

Formula: C₁₅₃H₂₂₅N₄₃O₄₉S

Purity: 99.56% - 99.91%

Color and Shape: Solid

Molecular weight: 3482.75

Ref: TM-T15389

Glucagon RS

CAS: 16941-32-5

Color and Shape: White Solid

Ref: 2K-104840002

Glucagon (1-29), bovine, human, porcine

CAS: 16941-32-5

Ref: BE-RMCP492007

Glucagon (1-29), bovine, human, porcine

CAS: 16941-32-5

Glucagon (1-29), bovine, human, porcine, is a peptide hormone, which is derived from bovine, human, and porcine sources. It comprises 29 amino acids and functions as a crucial regulator of glucose metabolism by promoting the increase of blood glucose levels. The mode of action involves binding to receptors on liver cells, activating adenylate cyclase, and subsequently increasing intracellular cyclic AMP. This cascade triggers glycogenolysis and gluconeogenesis, leading to elevated blood glucose.In scientific research, Glucagon (1-29), bovine, human, porcine, is utilized to study metabolic pathways and the regulation of glucose homeostasis. Its applications extend to diabetes research, where it serves as a model for understanding glucagon's role in insulin resistance and pancreatic beta-cell dysfunction. Furthermore, this product is employed in the development of therapeutic strategies for hypoglycemic events experienced by diabetic patients. It also serves as a tool in pharmacological studies to elucidate receptor-ligand interactions and signaling mechanisms in different species.

Formula: C₁₅₃H₂₂₅N₄₃O₄₉S

Purity: Min. 95%

Molecular weight: 3,482.78 g/mol

Ref: 3D-PG16975

Glucagon (Human)

CAS: 16941-32-5

Glucagon (Human) is a recombinant peptide hormone, which is synthesized to mimic the natural glucagon produced by alpha cells in the pancreas. This biopharmaceutical is derived from a DNA recombinant technology source, offering a high level of purity and consistency. Its mode of action involves binding to glucagon receptors on liver cells, stimulating glycogenolysis and gluconeogenesis. This results in the rapid conversion of glycogen into glucose, thereby raising blood sugar levels.Glucagon (Human) is primarily utilized in the treatment of severe hypoglycemia, especially in diabetic patients unable to consume oral glucose due to unconsciousness or confusion. Its application is critical in acute settings where rapid intervention is necessary to prevent neurological damage from prolonged hypoglycemia. Additionally, the research and clinical use of glucagon extend to investigating its potential in counteracting beta-blocker and calcium channel blocker overdoses, where it acts to increase cardiac output. This hormone's pharmaceutical development has provided a crucial tool in both emergency response and broader therapeutic research contexts.

Formula: C₁₅₃H₂₂₅N₄₃O₄₉S

Purity: Min. 95%

Molecular weight: 3,482.7 g/mol

Ref: 3D-PGL-4098-S

Glucagon

CAS: 16941-32-5

Formula: C₁₅₃H₂₂₅N₄₃O₄₉S

Molecular weight: 3482.8

Ref: ST-EA-CP-G38025

Glucagon RS

CAS: 16941-32-5

Color and Shape: White Solid

Ref: 2K-1048400021

Glucagon tifluoroacetic acid

CAS: 16941-32-5

Please enquire for more information about Glucagon tifluoroacetic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Formula: C₁₅₃H₂₂₅N₄₃O₄₉S•(CF₃CO₂H)x

Molecular weight: 3,482.75 g/mol

Ref: 3D-G-1000