CAS 1715-30-6

Alexidine dihydrochloride

Description:

Alexidine dihydrochloride is a synthetic compound primarily used as an antiseptic and disinfectant. It belongs to the class of biguanides, which are known for their antimicrobial properties. This substance is characterized by its ability to disrupt microbial cell membranes, making it effective against a broad spectrum of bacteria, fungi, and some viruses. Alexidine dihydrochloride is typically presented as a white to off-white powder and is soluble in water, which facilitates its application in various formulations, including mouthwashes and topical antiseptics. Its mechanism of action involves binding to the negatively charged components of microbial membranes, leading to cell lysis. Additionally, it is often favored in formulations due to its relatively low toxicity and irritation potential compared to other antiseptics. However, like all chemical agents, it should be used according to safety guidelines to minimize potential adverse effects. Overall, Alexidine dihydrochloride is valued in both clinical and consumer products for its efficacy in infection control.

Formula: C₂₆H₅₈Cl₂N₁₀

InChI: InChI=1/C26H56N10.2ClH/c1-5-9-15-21(7-3)19-33-25(29)35-23(27)31-17-13-11-12-14-18-32-24(28)36-26(30)34-20-22(8-4)16-10-6-2;;/h21-22H,5-20H2,1-4H3,(H5,27,29,31,33,35)(H5,28,30,32,34,36);2*1H

InChI key: InChIKey=BRJJFBHTDVWTCJ-UHFFFAOYSA-N

SMILES: C(CNC(NC(NCCCCCCNC(NC(NCC(CCCC)CC)=N)=N)=N)=N)(CCCC)CC.Cl

Synonyms:

• 1,6-Bis(2-ethylhexylbiguanido)hexane dihydrochloride
• 2,4,11,13-Tetraazatetradecanediimidamide, N,N''-bis(2-ethylhexyl)-3,12-diimino-, dihydrochloride
• 2,4,11,13-Tetraazatetradecanediimidamide, N1,N14-bis(2-ethylhexyl)-3,12-diimino-, hydrochloride (1:2)
• 2,4,11,13-Tetraazatetradecanediimidamide, N¹,N¹⁴-bis(2-ethylhexyl)-3,12-diimino-, hydrochloride (1:2)
• Alexidine dihydrochloride
• Alexidine hydrochloride
• Biguanide, 1,1′-hexamethylenebis[5-(2-ethylhexyl)-, dihydrochloride
• Hexamethylenebis(2-ethylhexyl)biguanide dihydrochloride
• N'',N''''''-hexane-1,6-diylbis[N'''-(2-ethylhexyl)(imidodicarbonimidic diamide)] dihydrochloride
• N,N''-Bis(2-ethylhexyl)-3,12-diimino-2,4,11,13-tetraazatetradecanediamidine dihydrochloride
• WIN-21904
• Alexidine dihydrochloride, N,N''''-Hexane-1,6-diylbis[N'-(2-ethylhex-1-yl)(imidodicarbonimidic diamide)] dihydrochloride
• N,N''-Bis(2-ethylhexyl)-3,12-diiMino-2,4,11,13-tetraazatetradecanediiMidaMide
• Bisguanidine
• Bisguadine
• 1,1'-Hexamethylenebis[5-(2-ethylhex-1-yl)]biguanide dihydrochloride
• N,N''-Bis(2-ethylhexyl)-3,12-diimino-2,4,11,13-tetraazatetradecanediimidamidedihydrochloride
• Compound-904
• Sterwin 904

Alexidine Dihydrochloride

CAS: 1715-30-6

Formula: C₂₆H₅₆N₁₀·2HCl

Purity: >98.0%(HPLC)(N)

Color and Shape: White to Almost white powder to crystaline

Molecular weight: 581.72

Ref: 3B-A3389

1,1'-Hexamethylenebis[5-(2-ethylhex-1-yl)]biguanide dihydrochloride

CAS: 1715-30-6

1,1'-Hexamethylenebis[5-(2-ethylhex-1-yl)]biguanide dihydrochloride

Formula: C₂₆H₅₆N₁₀·2ClH

Purity: ≥95%

Color and Shape: Solid-Powder

Molecular weight: 581.71172

Ref: 54-OR2503

Alexidine dihydrochloride

CAS: 1715-30-6

Alexidine dihydrochloride

Formula: C₂₆H₅₈Cl₂N₁₀

Purity: 99.5%

Molecular weight: 581.71

Ref: 54-BUP11753

Alexidine dihydrochloride

CAS: 1715-30-6

Alexidine dihydrochloride: antifungal, antibiofilm, targets PTPMT1 for mitochondrial apoptosis, potential cancer treatment.

Formula: C₂₆H₅₈Cl₂N₁₀

Purity: 99.32% - 99.81%

Color and Shape: Solid

Molecular weight: 581.71

Ref: TM-T14177

Alexidine dihydrochloride

CAS: 1715-30-6

Alexidine dihydrochloride

Formula: C₂₆H₅₆N₁₀·2ClH

Purity: By hplc: 99.5% (Typical Value in Batch COA)

Color and Shape: Solid

Molecular weight: 581.71172

Ref: 54-BIMI8260

Alexidine dihydrochloride

CAS: 1715-30-6

Formula: C₂₆H₅₆N₁₀·2HCl

Color and Shape: White to off-white powder

Molecular weight: 581.71

Ref: 7W-GP3723

N,N''-Bis(2-ethylhexyl)-3,12-diimino-2,4,11,13-Tetraazatetradecanediimidamide dihydrochloride

CAS: 1715-30-6

Formula: C₂₆H₅₈Cl₂N₁₀

Purity: 98%

Color and Shape: Solid

Molecular weight: 581.7117

Ref: IN-DA00ACX5

Alexidine Dihydrochloride

Controlled Product

CAS: 1715-30-6

Applications Alexidine Dihydrochloride has antibacterial, antiplaque properties against Streptococcus mutans, Actinomyces ciscosus, and Actinomyces naesludii.
References Coburn, R.A., et al.: J. Med. Chem., 21, 8, 829 (1978), Takayama, K., et al.: J. Biol. Chem., 269, 2241 (1994), Faure, P., et al.: Biochimie, 86, 411 (2004),

Formula: C₂₆H₅₆N₁₀·2ClH

Color and Shape: Neat

Molecular weight: 581.71

Ref: TR-A525000

Alexidine 2HCl

CAS: 1715-30-6

N,N''-Bis(2-ethylhexyl)-3,12-diimino-2,4,11,13-Tetraazatetradecanediimidamide dihydrochloride

Formula: C₂₆H₅₈Cl₂N₁₀

Purity: 98%

Molecular weight: 581.71

Ref: IN-DG284102

Alexidine dihydrochloride

CAS: 1715-30-6

Alexidine dihydrochloride is a metabolic agent that belongs to the group of antimicrobial agents. It is used in the treatment of cervical cancer, which is caused by human papilloma virus. Alexidine dihydrochloride inhibits the growth of cancer cells and has been shown to induce cell death in squamous cancer cells. It also inhibits microbial infection when combined with polymyxin B. This compound binds to microbial membranes, disrupting their function and inhibiting bacterial growth. Alexidine dihydrochloride has been shown to inhibit the synthesis of DNA, RNA, and protein by binding to specific sites on cellular ribosomes.

Formula: C₂₆H₅₆N₁₀·2HCl

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 581.71 g/mol

Ref: 3D-BAA71530

Alexidine Dihydrochloride extrapure, 96%

CAS: 1715-30-6

Formula: C₂₅H₅₈C₁₂N₁₀

Purity: min.96%

Color and Shape: White to off-white, Powder

Molecular weight: 581.73

Ref: SR-67482