CAS 172152-36-2

Ilaprazole

Description:

Ilaprazole is a medication classified as a proton pump inhibitor (PPI), primarily used for the treatment of conditions related to excessive stomach acid, such as gastroesophageal reflux disease (GERD) and peptic ulcers. Its mechanism of action involves the inhibition of the H+/K+ ATPase enzyme in the gastric parietal cells, effectively reducing gastric acid secretion. Ilaprazole is known for its stability and effectiveness, often exhibiting a longer duration of action compared to some other PPIs. The chemical structure of Ilaprazole includes a pyridine ring and a sulfinyl group, contributing to its pharmacological properties. It is typically administered orally and is well-absorbed in the gastrointestinal tract. Common side effects may include headache, nausea, and abdominal pain, although it is generally well-tolerated. As with other PPIs, long-term use may be associated with certain risks, such as vitamin B12 deficiency and gastrointestinal infections. Overall, Ilaprazole represents a valuable option in the management of acid-related disorders.

Formula: C₁₉H₁₈N₄O₂S

InChI: InChI=1S/C19H18N4O2S/c1-13-17(20-8-7-18(13)25-2)12-26(24)19-21-15-6-5-14(11-16(15)22-19)23-9-3-4-10-23/h3-11H,12H2,1-2H3,(H,21,22)

InChI key: InChIKey=HRRXCXABAPSOCP-UHFFFAOYSA-N

SMILES: S(CC1=C(C)C(OC)=CC=N1)(=O)C=2NC=3C(N2)=CC=C(C3)N4C=CC=C4

Synonyms:

• 1H-Benzimidazole, 2-[[(4-methoxy-3-methyl-2-pyridinyl)methyl]sulfinyl]-5-(1H-pyrrol-1-yl)-
• 1H-Benzimidazole, 2-[[(4-methoxy-3-methyl-2-pyridinyl)methyl]sulfinyl]-6-(1H-pyrrol-1-yl)-
• 2-((RS)-((4-Methoxy-3-methylpyridin-2-yl)methyl)sulfinyl)-5-(1H-pyrrol-1-yl)-1H-benzimidazole
• 2-[(4-Methoxy-3-methylpyridin-2-yl)methylsulfinyl]-6-pyrrol-1-yl-1H-benzimidazole
• 2-[[(4-Methoxy-3-methyl-2-pyridinyl)methyl]sulfinyl]-6-(1H-pyrrol-1-yl)-1H-benzimidazole
• 2-{[(4-methoxy-3-methylpyridin-2-yl)methyl]sulfinyl}-6-(1H-pyrrol-1-yl)-1H-benzimidazole
• Ilaprazole
• Ilaprazole [INN]
• Iy 81149
• Iy81149
• RS-ilaprazole

Ilaprazole

CAS: 172152-36-2

Formula: C₁₉H₁₈N₄O₂S

Purity: >98.0%(HPLC)(T)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 366.44

Ref: 3B-I1191

Ilaprazole

CAS: 172152-36-2

Formula: C₁₉H₁₈N₄O₂S

Color and Shape: Off-White Solid

Molecular weight: 366.44

Ref: 4Z-I-053001

2-(((4-Methoxy-3-Methylpyridin-2-Yl)Methyl)Sulfinyl)-6-(1H-Pyrrol-1-Yl)-1H-Benzo[D]Imidazole

CAS: 172152-36-2

2-(((4-Methoxy-3-Methylpyridin-2-Yl)Methyl)Sulfinyl)-6-(1H-Pyrrol-1-Yl)-1H-Benzo[D]Imidazole

Formula: C₁₉H₁₈N₄O₂S

Purity: 97%

Molecular weight: 366.44

Ref: 54-OR1027631

Ilaprazole

CAS: 172152-36-2

Ilaprazole

Purity: ≥98%

Molecular weight: 366.44g/mol

Ref: 54-BUP09721

2-[(4-methoxy-3-methylpyridin-2-yl)methylsulfinyl]-6-pyrrol-1-yl-1H-benzimidazole

CAS: 172152-36-2

Formula: C₁₉H₁₈N₄O₂S

Purity: 97%

Color and Shape: Solid

Molecular weight: 366.4368

Ref: IN-DA00ACA9

Ilaprazole

CAS: 172152-36-2

Formula: C₁₉H₁₈N₄O₂S

Color and Shape: Neat

Molecular weight: 366.44

Ref: 86-MM3745.00

Ilaprazole

CAS: 172152-36-2

2-(((4-Methoxy-3-methylpyridin-2-yl)methyl)sulfinyl)-6-(1H-pyrrol-1-yl)-1H-benzo[d]imidazole

Formula: C₁₉H₁₈N₄O₂S

Purity: 97%

Molecular weight: 366.44

Ref: IN-DG627732

Ilaprazole

CAS: 172152-36-2

Ilaprazole (IY-81149) is a proton pump inhibitor used in the treatment of dyspepsia gastroesophageal reflux disease (GORD/GERD) and duodenal ulcer.

Formula: C₁₉H₁₈N₄O₂S

Purity: 98.51% - 99.91%

Color and Shape: Solid

Molecular weight: 366.44

Ref: TM-T1756L

Ilaprazole

CAS: 172152-36-2

Formula: C₁₉H₁₈N₄O₂S

Molecular weight: 366.4

Ref: BE-RMCI027000

Ilaprazole

CAS: 172152-36-2

Formula: C₁₉H₁₈N₄O₂S

Molecular weight: 366.4

Ref: BE-RMCI45001

Ilaprazole

CAS: 172152-36-2

Purity: 97%

Molecular weight: 366.4400024

Ref: 10-F863340

Ilaprazole

Controlled Product

CAS: 172152-36-2

Applications Ilaprazole is a proton pump inhibitor (PPI) used in the treatment of dyspepsia, peptic ulcer disease (PUD), gastroesophageal reflux disease (GORD/GERD) and duodenal ulcer.
References Cao, S., et al.: Acta Pharmacol. Sin., 33, 1095 (2012); Wang, L., et al.: J. Clin. Gastroenterol., 45, 322 (2011)

Formula: C₁₉H₁₈N₄O₂S

Color and Shape: Neat

Molecular weight: 366.44

Ref: TR-I266400

Ilaprazole

CAS: 172152-36-2

Ilaprazole is a proton pump inhibitor, which is a synthetic derivative aimed at decreasing gastric acid secretion. It is primarily sourced from chemical synthesis involving benzimidazole derivatives. Ilaprazole functions by selectively inhibiting the H+/K+ ATPase enzyme system located at the gastric parietal cells. This mode of action leads to prolonged suppression of gastric acid secretion due to an extended plasma half-life, which in turn promotes a sustained therapeutic effect.

Formula: C₁₉H₁₈N₄O₂S

Purity: Min. 95%

Molecular weight: 366.44 g/mol

Ref: 3D-XGA15236

Ilaprazole

CAS: 172152-36-2

Formula: C₁₉H₁₈N₄O₂S

Molecular weight: 366.44

Ref: ST-EA-CP-I52000