CAS 172732-68-2: Varespladib

Formula: C₂₁H₂₀N₂O₅

InChI: InChI=1S/C21H20N2O5/c1-2-14-19(20(26)21(22)27)18-15(9-6-10-16(18)28-12-17(24)25)23(14)11-13-7-4-3-5-8-13/h3-10H,2,11-12H2,1H3,(H2,22,27)(H,24,25)

InChI key: InChIKey=BHLXTPHDSZUFHR-UHFFFAOYSA-N

SMILES: O=C(N)C(=O)C=1C=2C(OCC(=O)O)=CC=CC2N(C1CC)CC=3C=CC=CC3

Synonyms:

• ((3-(Aminooxoacetyl)-1-benzyl-2-ethyl-1H-indol-4-yl)oxy)acetic acid
• ({3-[amino(oxo)acetyl]-1-benzyl-2-ethyl-1H-indol-4-yl}oxy)acetic acid
• 2-[[3-(2-Amino-2-oxoacetyl)-2-ethyl-1-(phenylmethyl)-1H-indol-4-yl]oxy]acetic acid
• Acetic acid, ((3-(aminooxoacetyl)-2-ethyl-1-(phenylmethyl)-1H-indol-4-yl)oxy)-,
• Acetic acid, 2-[[3-(2-amino-2-oxoacetyl)-2-ethyl-1-(phenylmethyl)-1H-indol-4-yl]oxy]-
• Ly 315920
• Ly315920
• Unii-2Q3P98Dath
• Varepladib
• [[3-(2-Amino-1,2-dioxoethyl)-2-ethyl-1-(phenylmethyl)-1H-indol-4-yl]oxy]acetic acid
• sodium ({3-[amino(oxo)acetyl]-1-benzyl-2-ethyl-1H-indol-4-yl}oxy)acetate
• Varespladib

Varespladib

CAS: 172732-68-2

• Formula: C₂₁H₂₀N₂O₅
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 380.3939

Varespladib

CAS: 172732-68-2

• Formula: C₂₁H₂₀N₂O₅
• Purity: ≥ 98.0%
• Color and Shape: White to off-white solid
• Molecular weight: 380.39

Varespladib

CAS: 172732-68-2

Varespladib (LY315920) inhibits hnsPLA2 effectively (IC50=7 nM), studied for sickle cell, VOC, and acute coronary …

• Formula: C₂₁H₂₀N₂O₅
• Purity: 100% - ≥98%
• Color and Shape: Solid
• Molecular weight: 380.39

Varespladib

CAS: 172732-68-2

• Formula: C₂₁H₂₀N₂O₅
• Molecular weight: 380.40

Varespladib

CAS: 172732-68-2

Secretory phospholipase A2 inhibitorÂ

• Formula: C₂₁H₂₀N₂O₅
• Purity: Min. 98 Area-%
• Color and Shape: Powder
• Molecular weight: 380.39 g/mol

Varespladib-d5

CAS: 172732-68-2

• Formula: C₂₁D₅H₁₅N₂O₅
• Color and Shape: Neat
• Molecular weight: 385.425

2-[[3-(2-Amino-2-oxoacetyl)-2-ethyl-1-(phenylmethyl)-1H-indol-4-yl]oxy]Acetic Acid

CAS: 172732-68-2

Applications This compound is used as a PLA2 inhibitor (Phospholipase A2 Enzyme inhibitor). References Dennis, …

• Formula: C₂₁H₂₀N₂O₅
• Color and Shape: Neat
• Molecular weight: 380.39