Phospholipase
Phospholipases are a group of enzymes that hydrolyze phospholipids into fatty acids and other lipophilic substances, playing a critical role in membrane biology and the generation of signaling molecules. Inhibitors of phospholipases are used to study their role in inflammatory diseases, cardiovascular disorders, and neurodegeneration. These inhibitors are also valuable in exploring lipid signaling pathways and their implications in disease mechanisms. At CymitQuimica, we provide a variety of phospholipase inhibitors to support your research in inflammation, lipid metabolism, and cell signaling.
Found 86 products for "Phospholipase".
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Lp-PLA2-IN-1
CAS:Lp-PLA2-IN-1 suppresses Lp-PLA2, aiding in treating atherosclerosis and Alzheimer's.Formula:C21H17F5N4O3Purity:99.60%Color and Shape:White SolidMolecular weight:468.3767Omeprazole
CAS:Omeprazole (Losec) is a proton pump inhibitor (PPI), Omeprazole(Losec) is a potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor.Formula:C17H19N3O3SPurity:98.43% - 98.48%Color and Shape:Brown SolidMolecular weight:345.416ML349
CAS:ML349 is an inhibitor of LYPLA2 (IC50: 144 nM). ML349 is an effective and specific acyl protein thioesterase 2 (APT-2) inhibitor (Ki: 120 nM).Formula:C23H22N2O4S2Purity:99.59% - 99.88%Color and Shape:SolidMolecular weight:454.56Lansoprazole
CAS:Lansoprazole (A-65006) is a 2, 2, 2-trifluoroethoxypyridyl derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISONFormula:C16H14F3N3O2SPurity:99.18% - 99.84%Color and Shape:Yellow SolidMolecular weight:369.36Tris(2,4-di-tert-butylphenyl)phosphate
CAS:Tris(2,4-di-tert-butylphenyl)phosphate (TDTBPP) inhibits secretory phospholipase A2 (sPLA2) with anti-inflammatory effect. Cost-effective and quality-assured.Formula:C42H63O4PPurity:99.73%Color and Shape:SolidMolecular weight:662.92nSMase2-IN-1
nSMase2-IN-1 is an orally active inhibitor of Neutral sphingomyelinase 2 (nSMase2) with a potent IC50 value of 0.13 ± 0.06 μM.Formula:C12H17N5OPurity:98%Color and Shape:SolidMolecular weight:247.3A4333
A4333, a biotinylated derivative of A3373, selectively inhibits Phospholipase D1 (PLD1) while sparing PLD2.Purity:98%Color and Shape:Odour SolidA3373
CAS:A3373 is a novel inhibitor targeting both Phospholipase D1 (PLD1) and Phospholipase D2 (PLD2), demonstrating half maximal inhibitory concentrations (IC50) ofFormula:C17H9F7N2OPurity:98%Color and Shape:SolidMolecular weight:390.26Melittin Acetate
Melittin Acetate, a PLA2 activator, enhances low-weight PLA2 activity but not high-weight PLA2.Formula:C133H233N39O33Purity:99.65%Color and Shape:SolidMolecular weight:2906.51PLA2-IN-1
PLA2-IN-1 (Compound 7) is a potent and selective inhibitor of phospholipase A (PLA2) with an IC50 value of 1 nM. It effectively inhibits PLA2-induced coagulation disorders in vitro and shows potential for use as an antidote for snake bites caused by cobra venom.Color and Shape:Odour SolidDPTIP
CAS:DPTIP is an effective inhibitor of neutral sphingomyelinase 2 with an IC50 value of 30 nM.Formula:C21H18N2O3SPurity:99.88%Color and Shape:SolidMolecular weight:378.444Ref: TM-T60043
1mg45.00€2mg59.00€5mg100.00€1mL*10mM (DMSO)100.00€10mg144.00€25mg281.00€50mg461.00€100mg672.00€Compound 48/80 trihydrochloride
CAS:Compound 48/80 trihydrochloride (C48/80 trihydrochloride) is a mixture of N-methyl-p-methoxyphenethylamine and formaldehyde produced via a condensation reaction.Formula:C32H48Cl3N3O3Purity:98% - 99.24%Color and Shape:White SolidMolecular weight:629.1011,2-Bis(heptanoylthio)-sn-glycero-3-PG sodium
1,2-Bis(heptanoylthio)-sn-glycero-3-PG [1,2-Bis(heptanoylthio) glycerophosphatidylglycerol] sodium is a thioesterified phosphatidylglycerol derivative. It can be utilized to mimic phospholipase activity or serve as a probe molecule in membrane fusion studies.Color and Shape:Odour SolidAACOCF3
CAS:AACOCF3 (Arachidonyl trifluoromethyl ketone) is a cell-permeable trifluoromethyl ketone analog of arachidonic acid.Formula:C21H31F3OPurity:99% - 99%Color and Shape:SolidMolecular weight:356.47sPLA2 inhibitor 2
sPLA2 inhibitor 2 (compound 6a) is an sPLA2 inhibitor with an IC50 value of 0.0475 μM, making it valuable for diabetes research.Formula:C20H18N6O4S2Color and Shape:SolidMolecular weight:470.52VU533
CAS:VU533 is a NAPE-PLD activator, EC50=0.30 µM, boosts macrophage activity, potential in cardiometabolic diseases.Formula:C21H22FN3O3S2Purity:99.87%Color and Shape:SolidMolecular weight:447.551-Myristoyl-2-Linoleoyl-sn-glycero-3-PC
CAS:1-Myristoyl-2-Linoleoyl-sn-glycero-3-PC is a phospholipid identified in human plasma, characterized by the presence of Myristic acid and Linoleic acid at the sn-1 and sn-2 positions, respectively.Formula:C40H76NO8PColor and Shape:SolidMolecular weight:730.01LEI110
CAS:LEI110 inhibits PLA2G16 and HRASLS enzymes, Ki 20 nM, selectively targets related thiol hydrolases.Formula:C25H23F3N2O3Purity:98.66% - 99.01%Color and Shape:SolidMolecular weight:456.4569ASM-IN-3
CAS:ASM-IN-3 (Compound 21b) is a selective acid sphingomyelinase (ASM) inhibitor that can penetrate the blood-brain barrier, with an IC50 of 3.37 μM against purified human ASM. By inhibiting ASM activity in the hippocampus and promoting neurogenesis, ASM-IN-3 alleviates depressive-like behavior in reserpine-induced depressive rats.Formula:C17H13ClN2O4Color and Shape:SolidMolecular weight:344.75SB-435495
CAS:SB-435495 is a compound characterized by its potent, selective, reversible, and non-covalent inhibition of Lp-PLA2, demonstrating an IC50 value of 0.06 nM.Formula:C38H40F4N6O2SPurity:99.58%Color and Shape:White SolidMolecular weight:720.82
